GB1178958A - Production of Stable, High-Potency Human AHF - Google Patents
Production of Stable, High-Potency Human AHFInfo
- Publication number
- GB1178958A GB1178958A GB20604/68A GB2060468A GB1178958A GB 1178958 A GB1178958 A GB 1178958A GB 20604/68 A GB20604/68 A GB 20604/68A GB 2060468 A GB2060468 A GB 2060468A GB 1178958 A GB1178958 A GB 1178958A
- Authority
- GB
- United Kingdom
- Prior art keywords
- stable
- production
- precipitant
- precipitate
- cryoprecipitate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 101000798165 Homo sapiens Trichohyalin Proteins 0.000 title 1
- 102000047998 human TCHH Human genes 0.000 title 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 4
- 239000004471 Glycine Substances 0.000 abstract 2
- 239000002244 precipitate Substances 0.000 abstract 2
- 102100026735 Coagulation factor VIII Human genes 0.000 abstract 1
- 101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 abstract 1
- 239000004698 Polyethylene Substances 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 239000012461 cellulose resin Substances 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 abstract 1
- -1 polyethylene Polymers 0.000 abstract 1
- 229920000573 polyethylene Polymers 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
- 238000010257 thawing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63483967A | 1967-05-01 | 1967-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1178958A true GB1178958A (en) | 1970-01-28 |
Family
ID=24545372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB20604/68A Expired GB1178958A (en) | 1967-05-01 | 1968-05-01 | Production of Stable, High-Potency Human AHF |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS594402B1 (enrdf_load_stackoverflow) |
| BE (1) | BE713764A (enrdf_load_stackoverflow) |
| DE (1) | DE1767285C3 (enrdf_load_stackoverflow) |
| DK (1) | DK119626B (enrdf_load_stackoverflow) |
| ES (1) | ES353435A1 (enrdf_load_stackoverflow) |
| FR (1) | FR1589414A (enrdf_load_stackoverflow) |
| GB (1) | GB1178958A (enrdf_load_stackoverflow) |
| IT (1) | IT1048951B (enrdf_load_stackoverflow) |
| NL (1) | NL162838C (enrdf_load_stackoverflow) |
| SE (1) | SE375008B (enrdf_load_stackoverflow) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE29698E (en) | 1972-05-17 | 1978-07-11 | Baxter Travenol Laboratories, Inc. | Stabilization of AHF using heparin |
| EP0022052A3 (en) * | 1979-06-19 | 1981-11-11 | David Amrani | Process for the separation and isolation of the ahf fraction, the fibronectin fraction and the von willebrand's ristocetin cofactor fraction from blood plasma |
| EP0033582A3 (en) * | 1980-01-18 | 1981-11-18 | The Canadian Red Cross Society | Method of obtaining factor viii |
| EP0221566A3 (en) * | 1985-11-08 | 1987-10-07 | Baxter Travenol Laboratories, Inc. | Method for preparing antihemophilic factor (ahf) by cold precipitation and for improving solubility of recovered ahf product |
| EP0367840A1 (de) | 1988-11-05 | 1990-05-16 | Octapharma AG | Verfahren zur Herstellung eines hochreinen, nicht infektiösen Antihämophiliefaktors mittels Chromatographie |
| EP0412466A3 (en) * | 1989-08-07 | 1991-09-18 | Behringwerke Aktiengesellschaft | Preparation of a stable factor viii |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE348942B (enrdf_load_stackoverflow) * | 1970-06-02 | 1972-09-18 | Statens Bakteriologiska Labor | |
| DE2550011C2 (de) * | 1975-11-07 | 1982-11-25 | Behringwerke Ag, 3550 Marburg | Verfahren zur Herstellung eines antihämophilen Mittels |
| DK144731C (da) | 1976-07-30 | 1982-10-18 | Nordisk Insulinlab | Fremgangsmaade til isolering af proteinhormoner stammende fra humant hypofysevaev |
| FR2460305A2 (fr) * | 1979-06-29 | 1981-01-23 | Merieux Inst | Procede de preparation d'un concentre de facteur viii |
| DE3318521A1 (de) * | 1983-05-20 | 1984-11-22 | Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München | Verfahren zur herstellung eines antihaemophiliefaktor-konzentrats |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL286954A (enrdf_load_stackoverflow) * | 1962-01-03 |
-
1968
- 1968-04-17 BE BE713764D patent/BE713764A/xx not_active IP Right Cessation
- 1968-04-22 DK DK178768AA patent/DK119626B/da not_active IP Right Cessation
- 1968-04-22 DE DE1767285A patent/DE1767285C3/de not_active Expired
- 1968-04-23 FR FR1589414D patent/FR1589414A/fr not_active Expired
- 1968-04-25 SE SE6805574A patent/SE375008B/xx unknown
- 1968-04-29 IT IT36633/68A patent/IT1048951B/it active
- 1968-05-01 GB GB20604/68A patent/GB1178958A/en not_active Expired
- 1968-05-01 NL NL6806162.A patent/NL162838C/xx not_active IP Right Cessation
- 1968-05-02 ES ES353435A patent/ES353435A1/es not_active Expired
-
1973
- 1973-10-11 JP JP48114294A patent/JPS594402B1/ja active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE29698E (en) | 1972-05-17 | 1978-07-11 | Baxter Travenol Laboratories, Inc. | Stabilization of AHF using heparin |
| EP0022052A3 (en) * | 1979-06-19 | 1981-11-11 | David Amrani | Process for the separation and isolation of the ahf fraction, the fibronectin fraction and the von willebrand's ristocetin cofactor fraction from blood plasma |
| EP0033582A3 (en) * | 1980-01-18 | 1981-11-18 | The Canadian Red Cross Society | Method of obtaining factor viii |
| EP0221566A3 (en) * | 1985-11-08 | 1987-10-07 | Baxter Travenol Laboratories, Inc. | Method for preparing antihemophilic factor (ahf) by cold precipitation and for improving solubility of recovered ahf product |
| EP0367840A1 (de) | 1988-11-05 | 1990-05-16 | Octapharma AG | Verfahren zur Herstellung eines hochreinen, nicht infektiösen Antihämophiliefaktors mittels Chromatographie |
| EP0412466A3 (en) * | 1989-08-07 | 1991-09-18 | Behringwerke Aktiengesellschaft | Preparation of a stable factor viii |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1767285B2 (de) | 1980-12-04 |
| ES353435A1 (es) | 1969-09-16 |
| DK119626B (da) | 1971-02-01 |
| NL162838B (nl) | 1980-02-15 |
| FR1589414A (enrdf_load_stackoverflow) | 1970-03-31 |
| DE1767285A1 (de) | 1971-08-19 |
| NL162838C (nl) | 1980-07-15 |
| SE375008B (enrdf_load_stackoverflow) | 1975-04-07 |
| DE1767285C3 (de) | 1981-08-20 |
| IT1048951B (it) | 1980-12-20 |
| NL6806162A (enrdf_load_stackoverflow) | 1968-11-04 |
| JPS594402B1 (enrdf_load_stackoverflow) | 1984-01-30 |
| BE713764A (enrdf_load_stackoverflow) | 1968-09-16 |
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