GB1177957A - Production of Oxazepines and Thiazepines - Google Patents
Production of Oxazepines and ThiazepinesInfo
- Publication number
- GB1177957A GB1177957A GB4366769A GB4366769A GB1177957A GB 1177957 A GB1177957 A GB 1177957A GB 4366769 A GB4366769 A GB 4366769A GB 4366769 A GB4366769 A GB 4366769A GB 1177957 A GB1177957 A GB 1177957A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- piperazinyl
- hydroxy
- pyrrolidino
- piperidino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/20—[b, f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1,177,957. Tranquilizers. AMERICAN CYANAMID CO. 23 Dec., 1966, No. 43667/69. Divided out of 1,177,956. Heading A5B. [Also in Division C2] Pharmaceutical compositions, having tranquilizing and, in some instances, antidepressant and analgesic properties, comprise a compound of formula I: in which X is oxygen or sulphur, one of R 1 and R 2 is H, C 1-6 alkyl, C 1-6 alkoxy, halogen or trifluoromethyl and the other of R 1 and R 2 is H, C 1-6 alkoxy or halogen, Y is hydroxy, amino, C 1-6 alkylamino, di-(C 1-6 alkyl) amino, 1-piperazinyl, 4-C 1-6 alkyl-1-piperazinyl, 4-hydroxy-C 1-6 alkyl-1-piperazinyl, pyrrolidino, C 1-6 alkyl-pyrrolidino, piperidino, C 1-6 alkyl piperidino, morpholino or C 1-6 alkyl morpholino, R is C 1-6 alkyl, and n is 2, 3 or 4; or the -N(R)- C n H n -Y group taken together represents 1- piperazinyl; 4-C 1-6 alkyl-1-piperazinyl or 4- hydroxy-C 1-6 alkyl-1-piperazinyl, together with a pharmaceutically acceptable diluent or carrier. The compositions may be administered orally, e.g. in the form of tablets, capsules, dragees, drops, emulsions, suspensions and syrups, and in chocolate, candy or chewing gum, or parenterally in the form of aqueous solutions.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4366769A GB1177957A (en) | 1966-12-23 | 1966-12-23 | Production of Oxazepines and Thiazepines |
GB5771066A GB1177956A (en) | 1966-12-23 | 1966-12-23 | Production of Oxazepines and Thiazepines |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4366769A GB1177957A (en) | 1966-12-23 | 1966-12-23 | Production of Oxazepines and Thiazepines |
GB5771066A GB1177956A (en) | 1966-12-23 | 1966-12-23 | Production of Oxazepines and Thiazepines |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1177957A true GB1177957A (en) | 1970-01-14 |
Family
ID=26265220
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5771066A Expired GB1177956A (en) | 1966-12-23 | 1966-12-23 | Production of Oxazepines and Thiazepines |
GB4366769A Expired GB1177957A (en) | 1966-12-23 | 1966-12-23 | Production of Oxazepines and Thiazepines |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5771066A Expired GB1177956A (en) | 1966-12-23 | 1966-12-23 | Production of Oxazepines and Thiazepines |
Country Status (1)
Country | Link |
---|---|
GB (2) | GB1177956A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996018622A1 (en) * | 1994-12-12 | 1996-06-20 | Allelix Biopharmaceuticals Inc. | N-methyl piperazine compounds having dopamine receptor affinity |
US7491715B2 (en) | 2003-12-22 | 2009-02-17 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
-
1966
- 1966-12-23 GB GB5771066A patent/GB1177956A/en not_active Expired
- 1966-12-23 GB GB4366769A patent/GB1177957A/en not_active Expired
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996018622A1 (en) * | 1994-12-12 | 1996-06-20 | Allelix Biopharmaceuticals Inc. | N-methyl piperazine compounds having dopamine receptor affinity |
US5700445A (en) * | 1994-12-12 | 1997-12-23 | Allelix Biopharmaceuticals, Inc. | N-methyl piperazine compounds having dopamine receptor affinity |
US5968478A (en) * | 1994-12-12 | 1999-10-19 | Allelix Biopharmaceuticals, Inc. | N- methyl piperazine compounds having dopamine receptor affinity |
US7491715B2 (en) | 2003-12-22 | 2009-02-17 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
US7517871B2 (en) | 2003-12-22 | 2009-04-14 | Acadia Pharmaceuticals, Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
US7622461B2 (en) | 2003-12-22 | 2009-11-24 | Acadia Pharmaceuticals Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
Also Published As
Publication number | Publication date |
---|---|
GB1177956A (en) | 1970-01-14 |
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