GB1153792A - Pharmaceutical Compositions - Google Patents

Pharmaceutical Compositions

Info

Publication number
GB1153792A
GB1153792A GB4132566A GB4132566A GB1153792A GB 1153792 A GB1153792 A GB 1153792A GB 4132566 A GB4132566 A GB 4132566A GB 4132566 A GB4132566 A GB 4132566A GB 1153792 A GB1153792 A GB 1153792A
Authority
GB
United Kingdom
Prior art keywords
nhr
compositions
hydrogen
chlorophenyl
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4132566A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Charles Pfizer and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc
Publication of GB1153792A publication Critical patent/GB1153792A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/36—One oxygen atom
    • C07D263/42—One oxygen atom attached in position 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen

Abstract

1,153,792. Serotonin antagonists. CHAS. PFIZER & CO. Inc. 15 Sept., 1966 [12 Oct., 1965], No. 41325/66. Heading A5B. [Also in Division C2] Pharmaceutical compositions for lowering the level of 5-hydroxytryptamine in the body, comprise a p-chlorophenyl compound of the formula wherein R is hydrogen or a C 1 -C 5 alkyl group, Z is -C-; -CH-; or -CH- wherein R' # | | O OH NHR' is hydrogen or a C 1 -C 5 alkanoyl group; or, when Z is -CH, a pharmaceutically accept- | NHR' able acid addition salt thereof, together with a pharmaceutically acceptable carrier. The compositions may take the form of tablets, capsules, lozenges, troches, hard candies, powders, sprays, sterile aqueous or oily suspensions or solutions for injection, elixirs and syrups. Preferred compositions are those containing p-chlorophenyl-lactic or pyruvic acids, or p-chlorophenylalanine, and its N-acyl derivatives and esters.
GB4132566A 1965-10-12 1966-09-15 Pharmaceutical Compositions Expired GB1153792A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49533765A 1965-10-12 1965-10-12

Publications (1)

Publication Number Publication Date
GB1153792A true GB1153792A (en) 1969-05-29

Family

ID=23968253

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4132566A Expired GB1153792A (en) 1965-10-12 1966-09-15 Pharmaceutical Compositions

Country Status (2)

Country Link
FR (1) FR5734M (en)
GB (1) GB1153792A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113967416A (en) * 2021-10-29 2022-01-25 新疆医科大学第四附属医院 Dissolving method and application of high-concentration p-chlorophenylalanine

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0000382D0 (en) 2000-02-07 2000-02-07 Astrazeneca Ab New process

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113967416A (en) * 2021-10-29 2022-01-25 新疆医科大学第四附属医院 Dissolving method and application of high-concentration p-chlorophenylalanine

Also Published As

Publication number Publication date
FR5734M (en) 1968-01-22

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