GB1177648A - 09-Substituted-6beta,19- and 11beta,19-Steroid Oxides - Google Patents
09-Substituted-6beta,19- and 11beta,19-Steroid OxidesInfo
- Publication number
- GB1177648A GB1177648A GB5587466A GB5587466A GB1177648A GB 1177648 A GB1177648 A GB 1177648A GB 5587466 A GB5587466 A GB 5587466A GB 5587466 A GB5587466 A GB 5587466A GB 1177648 A GB1177648 A GB 1177648A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acyloxy
- oxo
- dec
- derivatives
- steroids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,177,648. Medicines comprising steroids. RESEARCH INSTITUTE FOR MEDICINE & CHEMISTRY, Inc. 13 Dec., 1966 [17 Dec., 1965], No. 55874/66. Heading A5B. [Also in Division C2] Pharmaceutical compositions comprise steroids of the skeletal formula: (wherein Y is oxo, OH or acyloxy; Z is OH, esterified OH, etherified OH or F; R is an oxygen atom which is also joined to the 6- or 11-position; either R<SP>1</SP> is optionally ketalised acetyl or monohaloacetyl and R<SP>2</SP> is H, OH or acyloxy, or R<SP>1</SP> is OH and R<SP>2</SP> is an optionally halo-substituted aliphatic hydrocarbon group; and R<SP>3</SP> is a substituent eliminatable with a hydrogen atom at the 4-position, or represents a carbon-carbon bond joined to the 4-position), and/or 3-ketals of such compounds wherein Y is OXO, together with a pharmaceutical carrier or excipient. The active ingredients are stated to possess antifertility and aldosteroneblocking activities. Administration may be oral, parenteral or rectal. The compositions may additionally include estrogenic or proestrogenic agents, progestational agents, carbonic anhydrase inhibitors (e.g. dichlorophenamide or acetazolamide derivatives), thiazide diuretics (e.g. trichlormethazide), xanthene diuretics, ethacrynic acid derivatvies, and/or triamterene derivatives. Reference has been directed by the Comptroller to Specification 1,046,242.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51469165A | 1965-12-17 | 1965-12-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1177648A true GB1177648A (en) | 1970-01-14 |
Family
ID=24048303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5587466A Expired GB1177648A (en) | 1965-12-17 | 1966-12-13 | 09-Substituted-6beta,19- and 11beta,19-Steroid Oxides |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE691320A (en) |
| CH (1) | CH587290A5 (en) |
| DE (2) | DE1793794A1 (en) |
| DK (1) | DK123407B (en) |
| FR (2) | FR1511151A (en) |
| GB (1) | GB1177648A (en) |
| IL (1) | IL27072A (en) |
| NL (1) | NL6617739A (en) |
| SE (1) | SE348190B (en) |
-
1966
- 1966-12-13 GB GB5587466A patent/GB1177648A/en not_active Expired
- 1966-12-16 DK DK653366A patent/DK123407B/en unknown
- 1966-12-16 BE BE691320D patent/BE691320A/xx unknown
- 1966-12-16 NL NL6617739A patent/NL6617739A/xx unknown
- 1966-12-16 SE SE1727966A patent/SE348190B/xx unknown
- 1966-12-16 FR FR87807A patent/FR1511151A/en not_active Expired
- 1966-12-16 IL IL2707266A patent/IL27072A/en unknown
- 1966-12-17 DE DE19661793794 patent/DE1793794A1/en active Pending
- 1966-12-17 DE DE19661593348 patent/DE1593348C3/en not_active Expired
- 1966-12-19 CH CH1812266A patent/CH587290A5/en not_active IP Right Cessation
-
1967
- 1967-03-16 FR FR99003A patent/FR6920M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1593348C3 (en) | 1975-03-06 |
| FR6920M (en) | 1969-05-05 |
| DE1793794A1 (en) | 1975-07-31 |
| FR1511151A (en) | 1968-01-26 |
| BE691320A (en) | 1967-06-16 |
| CH587290A5 (en) | 1977-04-29 |
| SE348190B (en) | 1972-08-28 |
| DE1593348B2 (en) | 1974-07-18 |
| NL6617739A (en) | 1967-06-19 |
| DK123407B (en) | 1972-06-19 |
| IL27072A (en) | 1972-07-26 |
| DE1593348A1 (en) | 1970-07-30 |
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