GB1141960A - 17-imidazolyl androstane derivatives - Google Patents
17-imidazolyl androstane derivativesInfo
- Publication number
- GB1141960A GB1141960A GB4668767A GB4668767A GB1141960A GB 1141960 A GB1141960 A GB 1141960A GB 4668767 A GB4668767 A GB 4668767A GB 4668767 A GB4668767 A GB 4668767A GB 1141960 A GB1141960 A GB 1141960A
- Authority
- GB
- United Kingdom
- Prior art keywords
- imidazolyl
- androstane derivatives
- oct
- formula
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
1,141,960. 17-lmidazolyl-androstane derivatives. SOC. FARMACEUTICI ITALIA. 12 Oct., 1967 [12 Oct., 1966], No. 46687/67. Heading C2U. Novel compounds of formula (wherein X-Y is -CH 2 -H 2 - or -CH= CH-; R is H 2 , H(OH) or O; R 1 is H,F or Cl; R 2 is H, F or CH 3 ; R 3 is H or C 1-10 carboxylic acyl; W is H or OH; Z is H, OH or CH 3 ; or W and Z are together a 16α,17α-isopropylidenedioxy group) are prepared from the corresponding 20-oxo-21-hydroxy-pregnenes by reaction with guanidine or a salt thereof, followed, if required, by N-acylation. The compounds of Formula I are stated to possess anti-inflammatory, antirheumatic and antiallergic activity and may be administered orally, parenterally, or topically in the form of pharmaceutical compositions with a liquid or solid vehicle.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2876666 | 1966-10-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1141960A true GB1141960A (en) | 1969-02-05 |
Family
ID=11224145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4668767A Expired GB1141960A (en) | 1966-10-12 | 1967-10-12 | 17-imidazolyl androstane derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1141960A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015071657A1 (en) * | 2013-11-14 | 2015-05-21 | The University Of Manchester | Selective glucocorticoid receptor ligands |
-
1967
- 1967-10-12 GB GB4668767A patent/GB1141960A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015071657A1 (en) * | 2013-11-14 | 2015-05-21 | The University Of Manchester | Selective glucocorticoid receptor ligands |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB1502544A (en) | Pharmaceutical composition | |
MY104375A (en) | Vitamin d derivatives and process for their preparation. | |
GB1369934A (en) | Process for the preparation of vincamine and vincamineanalogues | |
GB1141960A (en) | 17-imidazolyl androstane derivatives | |
GB1161629A (en) | Pregnadienes | |
GB1252286A (en) | ||
GB1255098A (en) | Derivatives of glycyrrhetinic acid | |
GB1074491A (en) | Novel processes for preparing steroid compounds, the compounds when thus prepared, novel steroid compounds thereby prepared, and pharmaceutical compositions containing the novel compounds | |
GB1112909A (en) | Ergoline derivatives | |
GB1141214A (en) | New derivatives of proscillaridin a | |
GB1397434A (en) | Evomonoside derivatives | |
IE37657B1 (en) | Derivatives of 6alpha-methyl-prednisolone processes for their preparation and compositions incorporating them | |
GB1355663A (en) | 19-nortestosterone 17- -p-substituted phenoxy-acetates | |
ES347368A1 (en) | Novel Gona-4,9,11-trienes, Processes for their Preparation, and Compositions incorporating them | |
GB1320549A (en) | 2-5,-nitro-2,-furfurylidene-thenylidene and pyrrolylmethylene -1-tetralones | |
ES449917A1 (en) | Substituted indanones | |
GB937722A (en) | New pyrazolopyrimidines and process for the preparation thereof | |
GB1268008A (en) | ESTERS OF p-BYPHENYLYLACETIC ACID | |
GB1195555A (en) | 3-Oximino Steroids and Method of Preparation | |
GB1177750A (en) | Novel Gona-4,9,11-Trienes, Processes for their Preparation, and Pharmaceutical Compositions Incorporating them | |
GB1382958A (en) | Azabicyclic esters of omega- 4-biphenylyl- alkanoic acids | |
GB1272688A (en) | Sulphamido-steroids and the preparation thereof | |
GB1054632A (en) | ||
GB1289956A (en) | ||
GB1311594A (en) | Diphenylacetic acid derivatives |