GB1175921A - Pyrrole Derivatives - Google Patents
Pyrrole DerivativesInfo
- Publication number
- GB1175921A GB1175921A GB6355/68A GB635568A GB1175921A GB 1175921 A GB1175921 A GB 1175921A GB 6355/68 A GB6355/68 A GB 6355/68A GB 635568 A GB635568 A GB 635568A GB 1175921 A GB1175921 A GB 1175921A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- nitropyrrole
- cyano
- imino group
- hydroxyethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003233 pyrroles Chemical class 0.000 title abstract 3
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 3
- JLTMCHYXBZXVHQ-UHFFFAOYSA-N pyrrolo[2,3-e]oxazine Chemical class O1N=CC=C2N=CC=C21 JLTMCHYXBZXVHQ-UHFFFAOYSA-N 0.000 abstract 3
- ZVVCRSWBCOBPKF-UHFFFAOYSA-N 5-nitro-1h-pyrrole-2-carbonitrile Chemical compound [O-][N+](=O)C1=CC=C(C#N)N1 ZVVCRSWBCOBPKF-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 238000007363 ring formation reaction Methods 0.000 abstract 2
- 229910052708 sodium Inorganic materials 0.000 abstract 2
- 239000011734 sodium Substances 0.000 abstract 2
- LMXHFXAFDMNKIM-UHFFFAOYSA-N 1-(2-hydroxyethyl)-5-nitropyrrole-2-carbonitrile Chemical compound OCCN1C(C#N)=CC=C1[N+]([O-])=O LMXHFXAFDMNKIM-UHFFFAOYSA-N 0.000 abstract 1
- RFQOPUYDLCMQCE-UHFFFAOYSA-N 1-(2-hydroxyethyl)-5-nitropyrrole-2-carboxamide Chemical compound NC(=O)C1=CC=C([N+]([O-])=O)N1CCO RFQOPUYDLCMQCE-UHFFFAOYSA-N 0.000 abstract 1
- LDLCZOVUSADOIV-UHFFFAOYSA-N 2-bromoethanol Chemical compound OCCBr LDLCZOVUSADOIV-UHFFFAOYSA-N 0.000 abstract 1
- OFODCYKDWRPCHV-UHFFFAOYSA-N 2-bromoethyl 5-nitro-1H-pyrrole-2-carboxylate Chemical compound [N+](=O)([O-])C1=CC=C(N1)C(=O)OCCBr OFODCYKDWRPCHV-UHFFFAOYSA-N 0.000 abstract 1
- SZIFAVKTNFCBPC-UHFFFAOYSA-N 2-chloroethanol Chemical compound OCCCl SZIFAVKTNFCBPC-UHFFFAOYSA-N 0.000 abstract 1
- 125000001340 2-chloroethyl group Chemical group [H]C([H])(Cl)C([H])([H])* 0.000 abstract 1
- BCHZICNRHXRCHY-UHFFFAOYSA-N 2h-oxazine Chemical group N1OC=CC=C1 BCHZICNRHXRCHY-UHFFFAOYSA-N 0.000 abstract 1
- HUKOJJJWOCAWDO-UHFFFAOYSA-N 3-(2-hydroxyethyl)-5-nitro-1H-pyrrole-2-carbonitrile Chemical compound OCCC1=C(NC(=C1)[N+](=O)[O-])C#N HUKOJJJWOCAWDO-UHFFFAOYSA-N 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical group [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 238000005904 alkaline hydrolysis reaction Methods 0.000 abstract 1
- 230000000842 anti-protozoal effect Effects 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008016 pharmaceutical coating Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000003495 polar organic solvent Substances 0.000 abstract 1
- 150000003109 potassium Chemical class 0.000 abstract 1
- 229910052700 potassium Chemical group 0.000 abstract 1
- 239000011591 potassium Chemical group 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/42—Nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR94179 | 1967-02-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1175921A true GB1175921A (en) | 1970-01-01 |
Family
ID=8624996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB6355/68A Expired GB1175921A (en) | 1967-02-08 | 1968-02-08 | Pyrrole Derivatives |
Country Status (17)
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5204332A (en) * | 1988-12-05 | 1993-04-20 | American Cyanamid Company | Pyrrole carbonitrile and nitropyrrole insecticidal and acaricidal and molluscicidal agents |
BR8906202A (pt) * | 1988-12-05 | 1990-09-25 | American Cyanamid Co | Processo e composicao para o controle de pragas de insetos,acaros e moluscos,composto para tal controle e processo para sua preparacao |
AUPP433398A0 (en) | 1998-06-25 | 1998-07-16 | Australian National University, The | Compounds and processes |
AU755919C (en) * | 1998-06-25 | 2004-07-29 | Australian National University, The | Syntheses of a variety of lamellarin compounds and analogues |
-
1967
- 1967-02-08 FR FR94179A patent/FR1592066A/fr not_active Expired
-
1968
- 1968-01-31 NL NL6801428A patent/NL6801428A/xx unknown
- 1968-02-06 SE SE01547/68A patent/SE333930B/xx unknown
- 1968-02-06 OA OA53177A patent/OA02738A/xx unknown
- 1968-02-06 IS IS1722A patent/IS735B6/is unknown
- 1968-02-07 IL IL29432A patent/IL29432A/xx unknown
- 1968-02-07 NO NO00480/68A patent/NO127578B/no unknown
- 1968-02-07 BE BE710476D patent/BE710476A/xx unknown
- 1968-02-07 CS CS9009A patent/CS149610B2/cs unknown
- 1968-02-07 LU LU55425D patent/LU55425A1/xx unknown
- 1968-02-07 CS CS939A patent/CS149609B2/cs unknown
- 1968-02-08 DE DE19681695667 patent/DE1695667A1/de active Pending
- 1968-02-08 SU SU1217467A patent/SU376943A3/ru active
- 1968-02-08 GB GB6355/68A patent/GB1175921A/en not_active Expired
- 1968-02-08 CH CH185168A patent/CH481102A/fr not_active IP Right Cessation
- 1968-02-08 ES ES350291A patent/ES350291A1/es not_active Expired
- 1968-02-08 AT AT120468A patent/AT273952B/de active
- 1968-02-08 YU YU0277/68A patent/YU31811B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SE333930B (enrdf_load_stackoverflow) | 1971-04-05 |
IL29432A (en) | 1971-05-26 |
BE710476A (enrdf_load_stackoverflow) | 1968-08-07 |
FR1592066A (enrdf_load_stackoverflow) | 1970-05-11 |
YU31811B (en) | 1973-12-31 |
IS1722A7 (is) | 1968-08-09 |
NO127578B (enrdf_load_stackoverflow) | 1973-07-16 |
OA02738A (fr) | 1970-12-15 |
DE1695667A1 (de) | 1971-06-16 |
CH481102A (fr) | 1969-11-15 |
NL6801428A (enrdf_load_stackoverflow) | 1968-08-09 |
AT273952B (de) | 1969-09-10 |
CS149610B2 (enrdf_load_stackoverflow) | 1973-07-25 |
SU376943A3 (enrdf_load_stackoverflow) | 1973-04-05 |
CS149609B2 (enrdf_load_stackoverflow) | 1973-07-25 |
ES350291A1 (es) | 1969-04-16 |
IS735B6 (is) | 1970-09-30 |
LU55425A1 (enrdf_load_stackoverflow) | 1968-10-09 |
YU27768A (en) | 1973-06-30 |
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