GB1174152A - Sulphanilamide Derivatives and Process for Their Production - Google Patents
Sulphanilamide Derivatives and Process for Their ProductionInfo
- Publication number
- GB1174152A GB1174152A GB03708/67A GB1370867A GB1174152A GB 1174152 A GB1174152 A GB 1174152A GB 03708/67 A GB03708/67 A GB 03708/67A GB 1370867 A GB1370867 A GB 1370867A GB 1174152 A GB1174152 A GB 1174152A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- monocycloaliphatic
- reaction
- amino
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical class NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 5
- 238000006243 chemical reaction Methods 0.000 abstract 4
- 150000007522 mineralic acids Chemical class 0.000 abstract 3
- 150000007524 organic acids Chemical class 0.000 abstract 3
- DISXFZWKRTZTRI-UHFFFAOYSA-N 4,5-dihydro-1h-imidazol-2-amine Chemical class NC1=NCCN1 DISXFZWKRTZTRI-UHFFFAOYSA-N 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- PZZRSEUDGCFXIH-UHFFFAOYSA-N 2-methylsulfanyl-4,5-dihydro-1h-imidazol-1-ium;iodide Chemical class I.CSC1=NCCN1 PZZRSEUDGCFXIH-UHFFFAOYSA-N 0.000 abstract 1
- YNSQQCZXQJUPTN-UHFFFAOYSA-N 4-imidazolidin-1-ylsulfonylaniline Chemical class S(=O)(C1=CC=C(C=C1)N)(=O)N1CNCC1 YNSQQCZXQJUPTN-UHFFFAOYSA-N 0.000 abstract 1
- 101710178035 Chorismate synthase 2 Proteins 0.000 abstract 1
- 101710152694 Cysteine synthase 2 Proteins 0.000 abstract 1
- -1 N-(2-substituted amino-ethyl)-guanidine Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- QPJDMGCKMHUXFD-UHFFFAOYSA-N cyanogen chloride Chemical compound ClC#N QPJDMGCKMHUXFD-UHFFFAOYSA-N 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000002218 hypoglycaemic effect Effects 0.000 abstract 1
- SDDKIZNHOCEXTF-UHFFFAOYSA-N methyl carbamimidothioate Chemical compound CSC(N)=N SDDKIZNHOCEXTF-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000009467 reduction Effects 0.000 abstract 1
- 238000006722 reduction reaction Methods 0.000 abstract 1
- 238000006894 reductive elimination reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/46—Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH428066A CH470397A (de) | 1966-03-24 | 1966-03-24 | Verfahren zur Herstellung neuer Derivate des Sulfanilamids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1174152A true GB1174152A (en) | 1969-12-17 |
Family
ID=4273162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB03708/67A Expired GB1174152A (en) | 1966-03-24 | 1967-03-23 | Sulphanilamide Derivatives and Process for Their Production |
Country Status (12)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014167446A1 (en) | 2013-04-10 | 2014-10-16 | OncoArendi Therapeutics Sp. z o.o. | Derivatives of 1-(substituted sulfonyl)-2-aminoimidazoline as antitumor and antiproliferative agents |
-
1966
- 1966-03-24 CH CH428066A patent/CH470397A/de not_active IP Right Cessation
-
1967
- 1967-03-20 FI FI82667A patent/FI48081C/fi active
- 1967-03-22 NO NO16742267A patent/NO121400B/no unknown
- 1967-03-22 DK DK154367A patent/DK116133B/da unknown
- 1967-03-23 IL IL2767467A patent/IL27674A/xx unknown
- 1967-03-23 SE SE412067A patent/SE339476B/xx unknown
- 1967-03-23 GR GR670136364A patent/GR36364B/el unknown
- 1967-03-23 GB GB03708/67A patent/GB1174152A/en not_active Expired
- 1967-03-23 AT AT280467A patent/AT266121B/de active
- 1967-03-23 DE DE19671695014 patent/DE1695014A1/de active Pending
- 1967-03-23 ES ES338403A patent/ES338403A1/es not_active Expired
- 1967-03-24 FR FR1586813D patent/FR1586813A/fr not_active Expired
- 1967-06-23 FR FR111636A patent/FR6520M/fr not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014167446A1 (en) | 2013-04-10 | 2014-10-16 | OncoArendi Therapeutics Sp. z o.o. | Derivatives of 1-(substituted sulfonyl)-2-aminoimidazoline as antitumor and antiproliferative agents |
| US8981114B2 (en) | 2013-04-10 | 2015-03-17 | OncoArendi Therapeutics Sp. z.o.o. | Derivatives of 1-(substituted sulfonyl)-2-aminoimidazoline as antitumor and antiproliferative agents |
| US9095575B2 (en) | 2013-04-10 | 2015-08-04 | OncoArendi Therapeutics Sp. z o.o. | Derivatives of 1-(substituted sulfonyl)-2-aminoimidazoline as antitumor and antiproliferative agents |
Also Published As
| Publication number | Publication date |
|---|---|
| NO121400B (enrdf_load_stackoverflow) | 1971-02-22 |
| SE339476B (enrdf_load_stackoverflow) | 1971-10-11 |
| FR6520M (enrdf_load_stackoverflow) | 1968-12-09 |
| FI48081B (enrdf_load_stackoverflow) | 1974-02-28 |
| FR1586813A (enrdf_load_stackoverflow) | 1970-03-06 |
| FI48081C (fi) | 1974-06-10 |
| AT266121B (de) | 1968-11-11 |
| ES338403A1 (es) | 1968-04-01 |
| CH470397A (de) | 1969-03-31 |
| GR36364B (el) | 1969-02-04 |
| DK116133B (da) | 1969-12-15 |
| DE1695014A1 (de) | 1972-04-27 |
| IL27674A (en) | 1971-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |