GB1162185A - Therapeutic Compositions - Google Patents

Therapeutic Compositions

Info

Publication number
GB1162185A
GB1162185A GB1220467A GB1220467A GB1162185A GB 1162185 A GB1162185 A GB 1162185A GB 1220467 A GB1220467 A GB 1220467A GB 1220467 A GB1220467 A GB 1220467A GB 1162185 A GB1162185 A GB 1162185A
Authority
GB
United Kingdom
Prior art keywords
radical
march
hydroxy
phenyl
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1220467A
Inventor
Thomas Joseph Macek
Carl Edward Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1162185A publication Critical patent/GB1162185A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,162,185. Compositions for treating gout. MERCK & CO. Inc. 15 March, 1967 [21 March, 1966], No. 12204/67. Addition to 1072771. Heading ASB. Pharmaceutical compositions for treating gout comprise 4-hydroxy-pyrazolo-(3, 4-d)- pyrimidine and an inidolyl aliphatic acid of the general formula: wherein R 1 is a p-chlorobenzoyl, p-chloro- 'benzyl, p-methylthiobenzoyl or p-methylthiobenzyl radical, R 3 is H or Me, R 5 is a methoxy or dialkylamino radical and M is a hydroxy, benzyloxy, C 1-5 alkoxy or an OZ radical where Z is a pharmaceutically acceptable cation. They may be in conventional forms for oral and parenteral administration and may include other uricosuric agents eg a dialkylsulplamoyl benzoic acid; phenyl-quinoline carboxylic acid; an amino chloro-benzoxazole or a phenyl butazone.
GB1220467A 1966-03-21 1967-03-15 Therapeutic Compositions Expired GB1162185A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53571266A 1966-03-21 1966-03-21

Publications (1)

Publication Number Publication Date
GB1162185A true GB1162185A (en) 1969-08-20

Family

ID=24135454

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1220467A Expired GB1162185A (en) 1966-03-21 1967-03-15 Therapeutic Compositions

Country Status (3)

Country Link
BE (1) BE695881A (en)
GB (1) GB1162185A (en)
NL (1) NL6703524A (en)

Also Published As

Publication number Publication date
NL6703524A (en) 1967-09-22
BE695881A (en) 1967-09-21

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Legal Events

Date Code Title Description
PS Patent sealed
PE Patent expired