GB1155037A - Salts of Tetracycline Antibiotics - Google Patents

Info

Publication number

GB1155037A

GB1155037A GB30878/66A GB3087866A GB1155037A GB 1155037 A GB1155037 A GB 1155037A GB 30878/66 A GB30878/66 A GB 30878/66A GB 3087866 A GB3087866 A GB 3087866A GB 1155037 A GB1155037 A GB 1155037A

Authority

GB

United Kingdom

Prior art keywords

tetracycline

acid

sulphate

salt

salts

Prior art date

1965-07-08

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Links

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• 150000003839 salts Chemical class 0.000 title abstract 8
• 229940072172 tetracycline antibiotic Drugs 0.000 title abstract 5
• 239000004098 Tetracycline Substances 0.000 abstract 7
• 239000002253 acid Substances 0.000 abstract 7
• 229960002180 tetracycline Drugs 0.000 abstract 7
• 229930101283 tetracycline Natural products 0.000 abstract 7
• 235000019364 tetracycline Nutrition 0.000 abstract 7
• -1 tetracycline cetyl sulphate Chemical class 0.000 abstract 4
• 150000002148 esters Chemical class 0.000 abstract 3
• 150000003522 tetracyclines Chemical class 0.000 abstract 3
• LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
• 125000003342 alkenyl group Chemical group 0.000 abstract 2
• 125000000217 alkyl group Chemical group 0.000 abstract 2
• DHPRQBPJLMKORJ-XRNKAMNCSA-N (4s,4as,5as,6s,12ar)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]4(O)C(=O)C3=C(O)C2=C1O DHPRQBPJLMKORJ-XRNKAMNCSA-N 0.000 abstract 1
• FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
• 239000004100 Oxytetracycline Substances 0.000 abstract 1
• QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
• 125000004432 carbon atom Chemical group C* 0.000 abstract 1
• CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 abstract 1
• 150000001875 compounds Chemical class 0.000 abstract 1
• 150000002334 glycols Chemical class 0.000 abstract 1
• WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
• VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
• 229960000625 oxytetracycline Drugs 0.000 abstract 1
• 239000008194 pharmaceutical composition Substances 0.000 abstract 1
• HMEYVGGHISAPJR-IAHYZSEUSA-N rolitetracycline Chemical compound O=C([C@@]1(O)C(O)=C2[C@@H]([C@](C3=CC=CC(O)=C3C2=O)(C)O)C[C@H]1[C@@H](C=1O)N(C)C)C=1C(=O)NCN1CCCC1 HMEYVGGHISAPJR-IAHYZSEUSA-N 0.000 abstract 1
• GGHPAKFFUZUEKL-UHFFFAOYSA-M sodium;hexadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCOS([O-])(=O)=O GGHPAKFFUZUEKL-UHFFFAOYSA-M 0.000 abstract 1
• NWZBFJYXRGSRGD-UHFFFAOYSA-M sodium;octadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCCCOS([O-])(=O)=O NWZBFJYXRGSRGD-UHFFFAOYSA-M 0.000 abstract 1
• 239000002904 solvent Substances 0.000 abstract 1
• KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 abstract 1
• 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
• 229940095064 tartrate Drugs 0.000 abstract 1
• VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
• 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
• 239000008158 vegetable oil Substances 0.000 abstract 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Cited By (4)