GB1154675A - Chlorination. - Google Patents
Chlorination.Info
- Publication number
- GB1154675A GB1154675A GB147668A GB147668A GB1154675A GB 1154675 A GB1154675 A GB 1154675A GB 147668 A GB147668 A GB 147668A GB 147668 A GB147668 A GB 147668A GB 1154675 A GB1154675 A GB 1154675A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxy
- dichloro
- quinaldine
- quinoline
- jan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000005660 chlorination reaction Methods 0.000 title 1
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- WDFKMLRRRCGAKS-UHFFFAOYSA-N chloroxine Chemical compound C1=CN=C2C(O)=C(Cl)C=C(Cl)C2=C1 WDFKMLRRRCGAKS-UHFFFAOYSA-N 0.000 abstract 2
- SMUQFGGVLNAIOZ-UHFFFAOYSA-N quinaldine Chemical compound C1=CC=CC2=NC(C)=CC=C21 SMUQFGGVLNAIOZ-UHFFFAOYSA-N 0.000 abstract 2
- NBYLBWHHTUWMER-UHFFFAOYSA-N 2-Methylquinolin-8-ol Chemical compound C1=CC=C(O)C2=NC(C)=CC=C21 NBYLBWHHTUWMER-UHFFFAOYSA-N 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 239000005725 8-Hydroxyquinoline Substances 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- GPTXWRGISTZRIO-UHFFFAOYSA-N chlorquinaldol Chemical compound ClC1=CC(Cl)=C(O)C2=NC(C)=CC=C21 GPTXWRGISTZRIO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 229960003540 oxyquinoline Drugs 0.000 abstract 1
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
1,154,675. 5,7 - Dichloro - 8 - hydroxy quinoline and quinaldine. RUTGERSWERKE UND TEERVERWERTUNG A.G. 10 Jan., 1968 [11 Jan., 1967], No. 1476/68. Heading C2C. 5,7 - Dichloro - 8 - hydroxy - quinoline or 5,7- dichloro-8-hydroxy-quinaldine is made by chlorinating a solution of 8-hydroxy quinoline and 8- hydroxy quinaldine in chloroform with a molar excess of chlorine in the presence of 0À5-5% wt. of iodine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DER0045033 | 1967-01-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1154675A true GB1154675A (en) | 1969-06-11 |
Family
ID=7407482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB147668A Expired GB1154675A (en) | 1967-01-11 | 1968-01-10 | Chlorination. |
Country Status (3)
Country | Link |
---|---|
CH (1) | CH481915A (en) |
FR (1) | FR1549819A (en) |
GB (1) | GB1154675A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL422265A1 (en) * | 2017-07-18 | 2019-01-28 | Valeant Pharmaceuticals Ireland | Method for producing chloroquinaldol with increased purity |
-
1967
- 1967-12-22 CH CH1804267A patent/CH481915A/en not_active IP Right Cessation
- 1967-12-22 FR FR1549819D patent/FR1549819A/fr not_active Expired
-
1968
- 1968-01-10 GB GB147668A patent/GB1154675A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL422265A1 (en) * | 2017-07-18 | 2019-01-28 | Valeant Pharmaceuticals Ireland | Method for producing chloroquinaldol with increased purity |
Also Published As
Publication number | Publication date |
---|---|
DE1695608A1 (en) | 1972-03-02 |
FR1549819A (en) | 1968-12-13 |
CH481915A (en) | 1969-11-30 |
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