GB1153555A - Preparation of a Sulphur-Containing Pyridine Derivative - Google Patents

Preparation of a Sulphur-Containing Pyridine Derivative

Info

Publication number
GB1153555A
GB1153555A GB712568A GB712568A GB1153555A GB 1153555 A GB1153555 A GB 1153555A GB 712568 A GB712568 A GB 712568A GB 712568 A GB712568 A GB 712568A GB 1153555 A GB1153555 A GB 1153555A
Authority
GB
United Kingdom
Prior art keywords
carbon atoms
preparation
pyridine derivative
sulphur
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB712568A
Inventor
Gustav Schorre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck KGaA
Original Assignee
E Merck AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E Merck AG filed Critical E Merck AG
Publication of GB1153555A publication Critical patent/GB1153555A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,153,555. Sulphur pyridine derivative. E. MERCK A.G. 13 Feb., 1968 [25 March, 1967], No. 7125/68. Heading C2C. A process for the preparation of compound I herein and its salts, which comprises treating a compound of the Formula II in which R 1 and R 2 , which may be the same or different, are hydrogen or acyl groups or together form the divalent radical R 3 and R 4 , which may be the same or different, are hydrogen or alkyl groups containing up to 5 carbon atoms or together form an alkylidene group containing up to 5 carbon atoms or, together with the carbon atoms to which they are attached, form a 5- or 6-membered hydrocarbon ring, and m is an alkali metal, with an acidic medium and then adjusting the reaction mixture to a neutral, weakly acidic or weakly alkaline pH and, if desired, converting the product of Formula I obtained to an acid addition or quaternary ammonium salt thereof.
GB712568A 1967-03-25 1968-02-13 Preparation of a Sulphur-Containing Pyridine Derivative Expired GB1153555A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEM0073338 1967-03-25

Publications (1)

Publication Number Publication Date
GB1153555A true GB1153555A (en) 1969-05-29

Family

ID=7314979

Family Applications (1)

Application Number Title Priority Date Filing Date
GB712568A Expired GB1153555A (en) 1967-03-25 1968-02-13 Preparation of a Sulphur-Containing Pyridine Derivative

Country Status (10)

Country Link
BE (1) BE711087A (en)
CH (1) CH494759A (en)
CS (1) CS150572B2 (en)
ES (1) ES351960A1 (en)
FR (1) FR1568119A (en)
GB (1) GB1153555A (en)
IL (1) IL29534A (en)
NL (1) NL151074B (en)
SE (1) SE336791B (en)
YU (1) YU32925B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100509787C (en) * 2006-01-20 2009-07-08 山东轩竹医药科技有限公司 New pharmaceutically acceptable salt of pyritinol, and a preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100509787C (en) * 2006-01-20 2009-07-08 山东轩竹医药科技有限公司 New pharmaceutically acceptable salt of pyritinol, and a preparation method thereof

Also Published As

Publication number Publication date
IL29534A (en) 1971-07-28
YU32925B (en) 1975-12-31
DE1695402A1 (en) 1971-03-18
BE711087A (en) 1968-07-01
YU49468A (en) 1975-06-30
CS150572B2 (en) 1973-09-04
NL151074B (en) 1976-10-15
DE1695402B2 (en) 1975-07-24
SE336791B (en) 1971-07-19
CH494759A (en) 1970-08-15
NL6802320A (en) 1968-09-26
ES351960A1 (en) 1969-06-01
FR1568119A (en) 1969-05-23

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