GB1153071A - Process for the preparation of New Therapeutically Active Basic Ethers - Google Patents
Process for the preparation of New Therapeutically Active Basic EthersInfo
- Publication number
- GB1153071A GB1153071A GB3568166A GB3568166A GB1153071A GB 1153071 A GB1153071 A GB 1153071A GB 3568166 A GB3568166 A GB 3568166A GB 3568166 A GB3568166 A GB 3568166A GB 1153071 A GB1153071 A GB 1153071A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- formula
- alkyl
- preparation
- aug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1,153,071. Basic ethers. EGYESULT GYOGYSZER ES TAPSZERGYAR. 9 Aug., 1966 [12 Aug., 1965], No. 35681/66. Heading C2C. Novel compounds I of Formula I, in which R is C 4-15 alkyl, C 4-7 cycloalkyl or C 4-7 cycloalkyl- C 1-3 alkyl, A is C 1-4 alkylene, Z is di(C 1-3 alkyl)- amino and n is 2 to 8, and acid addition salts and quaternary ammonium derivatives thereof, are prepared by (a) reacting a compound II of Formula II, or a metal derivative thereof, with a compound of formula Hal-A-Y, in which Hal is halogen and Y is hydroxy or halogen or has the same meaning as Z, or (b) reacting a reactive ester of a compound II with a compound of formula HO-A-Y, if necessary, converting the atom or group Y in the product obtained into the desired group Z by known methods and, if desired converting a compound I into an acid addition salt or quaternary ammonium derivative. Compounds I are stated to have spasmolytic, minor tranquillizing, local anaesthetic and ulcer-inhibiting effects.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUEE001184 | 1965-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1153071A true GB1153071A (en) | 1969-05-21 |
Family
ID=10995182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3568166A Expired GB1153071A (en) | 1965-08-12 | 1966-08-09 | Process for the preparation of New Therapeutically Active Basic Ethers |
Country Status (7)
| Country | Link |
|---|---|
| AT (1) | AT270612B (en) |
| CH (1) | CH489452A (en) |
| DE (1) | DE1568462A1 (en) |
| FR (1) | FR5722M (en) |
| GB (1) | GB1153071A (en) |
| NL (1) | NL146788B (en) |
| SE (1) | SE351628B (en) |
-
1966
- 1966-07-26 AT AT712166A patent/AT270612B/en active
- 1966-08-01 CH CH1109966A patent/CH489452A/en not_active IP Right Cessation
- 1966-08-03 DE DE19661568462 patent/DE1568462A1/en active Pending
- 1966-08-05 NL NL6611088A patent/NL146788B/en not_active IP Right Cessation
- 1966-08-09 GB GB3568166A patent/GB1153071A/en not_active Expired
- 1966-08-09 SE SE1077466A patent/SE351628B/xx unknown
- 1966-08-11 FR FR72777A patent/FR5722M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL6611088A (en) | 1967-02-13 |
| SE351628B (en) | 1972-12-04 |
| NL146788B (en) | 1975-08-15 |
| FR5722M (en) | 1968-01-22 |
| CH489452A (en) | 1970-04-30 |
| AT270612B (en) | 1969-05-12 |
| DE1568462A1 (en) | 1970-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed |