GB1148453A - Steroid compounds - Google Patents

Steroid compounds

Info

Publication number
GB1148453A
GB1148453A GB2048366A GB2048366A GB1148453A GB 1148453 A GB1148453 A GB 1148453A GB 2048366 A GB2048366 A GB 2048366A GB 2048366 A GB2048366 A GB 2048366A GB 1148453 A GB1148453 A GB 1148453A
Authority
GB
United Kingdom
Prior art keywords
recovered
reaction mixture
steroid compounds
steroid
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2048366A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of GB1148453A publication Critical patent/GB1148453A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)

Abstract

1,148,453. Steroids. TAKEDA CHEMICAL INDUSTRIES Ltd. 9 May, 1966 [8 May, 1965; 9 June, 1965], No. 20483/66. Heading C2U. 21-Phosphates of steroid compounds having a 20-ketopregnane skeleton are obtained in a process in which a 21-hydroxy steroid is allowed to react with pyrophosphoryl tetrachloride, the reaction mixture is subjected to hydrolysis, and the desired compound is recovered from the reaction mixture. The reaction may be effected in a solvent, e.g. tetrahydrofuran, dioxane, pyridine, acetonitrile, hydrocarbons or phenols at room temperature or with cooling. The products may be recovered by adsorption on active charcoal followed by extraction.
GB2048366A 1965-05-08 1966-05-09 Steroid compounds Expired GB1148453A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2704265 1965-05-08
JP3455665 1965-06-09

Publications (1)

Publication Number Publication Date
GB1148453A true GB1148453A (en) 1969-04-10

Family

ID=26364917

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2048366A Expired GB1148453A (en) 1965-05-08 1966-05-09 Steroid compounds

Country Status (3)

Country Link
DE (1) DE1593578C2 (en)
GB (1) GB1148453A (en)
NL (2) NL6606218A (en)

Also Published As

Publication number Publication date
DE1593578C2 (en) 1972-06-08
NL6606218A (en) 1966-11-10
NL128598C (en)
DE1593578A1 (en) 1971-11-04

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