GB1144060A - Novel phthalimidine derivatives and a process for the manufacture and conversion thereof - Google Patents
Novel phthalimidine derivatives and a process for the manufacture and conversion thereofInfo
- Publication number
- GB1144060A GB1144060A GB5320367A GB5320367A GB1144060A GB 1144060 A GB1144060 A GB 1144060A GB 5320367 A GB5320367 A GB 5320367A GB 5320367 A GB5320367 A GB 5320367A GB 1144060 A GB1144060 A GB 1144060A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- novel
- nov
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
1,144,060. N-aminoethylisoindoline derivatives. F. HOFFMANN-LA ROCHE & CO. A.G. 22 Nov., 1967 [30 Nov., 1966], No. 53203/67. Heading C2C. Novel compounds of formula wherein R<SP>1</SP>, R<SP>2</SP>, R<SP>3</SP> and R<SP>4</SP> each represent a hydrogen or halogen atom or CF 3 , C 1-7 alkoxy, C 1-7 alkyl, OH, amino or mono- or di-(C 1-7 )- alkylamino groups and pharmaceutically acceptable salts thereof are prepared either by reacting ethylenediamine with a compound of formula or by action of hydrogen in presence of a catalyst on a compound of formula in both cases optionally with salt formation. The novel compounds are used to prepare compounds of formula by reducing the keto group for example with an alkali metal/hydride complex. Pharmaceutical compositions in conventional forms for enteral or parenteral administration and having analgesic, antipyretic, antiedematous and antidepressant activity comprise an above novel compound and a carrier or excipient therefor.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59784066A | 1966-11-30 | 1966-11-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1144060A true GB1144060A (en) | 1969-03-05 |
Family
ID=24393137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5320367A Expired GB1144060A (en) | 1966-11-30 | 1967-11-22 | Novel phthalimidine derivatives and a process for the manufacture and conversion thereof |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE707091A (en) |
| GB (1) | GB1144060A (en) |
| NL (1) | NL6715501A (en) |
-
1967
- 1967-11-15 NL NL6715501A patent/NL6715501A/xx unknown
- 1967-11-22 GB GB5320367A patent/GB1144060A/en not_active Expired
- 1967-11-27 BE BE707091D patent/BE707091A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE707091A (en) | 1968-05-27 |
| NL6715501A (en) | 1968-05-31 |
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