GB1141169A - New xanthine derivatives and process for the preparation thereof - Google Patents
New xanthine derivatives and process for the preparation thereofInfo
- Publication number
- GB1141169A GB1141169A GB19760/66A GB1976066A GB1141169A GB 1141169 A GB1141169 A GB 1141169A GB 19760/66 A GB19760/66 A GB 19760/66A GB 1976066 A GB1976066 A GB 1976066A GB 1141169 A GB1141169 A GB 1141169A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formaldehyde
- under reflux
- preparation
- theophylline
- xanthine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title 1
- 229940083747 low-ceiling diuretics xanthine derivative Drugs 0.000 title 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 9
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical class O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000010992 reflux Methods 0.000 abstract 2
- BGJSXRVXTHVRSN-UHFFFAOYSA-N 1,3,5-trioxane Chemical group C1OCOCO1 BGJSXRVXTHVRSN-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000002921 anti-spasmodic effect Effects 0.000 abstract 1
- 229940124575 antispasmodic agent Drugs 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000000496 cardiotonic agent Substances 0.000 abstract 1
- 230000003177 cardiotonic effect Effects 0.000 abstract 1
- 239000003218 coronary vasodilator agent Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 229940030606 diuretics Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 229960000278 theophylline Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR15868A FR1455103A (fr) | 1965-05-05 | 1965-05-05 | Nouveaux dérivés de xanthine et procédé de préparation |
| FR23094A FR4585M (enrdf_load_stackoverflow) | 1965-05-05 | 1965-07-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1141169A true GB1141169A (en) | 1969-01-29 |
Family
ID=26163612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB19760/66A Expired GB1141169A (en) | 1965-05-05 | 1966-05-04 | New xanthine derivatives and process for the preparation thereof |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE680346A (enrdf_load_stackoverflow) |
| FR (2) | FR1455103A (enrdf_load_stackoverflow) |
| GB (1) | GB1141169A (enrdf_load_stackoverflow) |
| NL (1) | NL6606108A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2073290A1 (en) * | 1969-12-30 | 1971-10-01 | Centre Etd Ind Pharma | 7-methyl-2,2-dimethyl-3-oxopiperazino theophylline - with bronchodilatory, diuretic, and other activities |
-
1965
- 1965-05-05 FR FR15868A patent/FR1455103A/fr not_active Expired
- 1965-07-01 FR FR23094A patent/FR4585M/fr not_active Expired
-
1966
- 1966-04-29 BE BE680346D patent/BE680346A/xx unknown
- 1966-05-04 GB GB19760/66A patent/GB1141169A/en not_active Expired
- 1966-05-05 NL NL6606108A patent/NL6606108A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2073290A1 (en) * | 1969-12-30 | 1971-10-01 | Centre Etd Ind Pharma | 7-methyl-2,2-dimethyl-3-oxopiperazino theophylline - with bronchodilatory, diuretic, and other activities |
Also Published As
| Publication number | Publication date |
|---|---|
| BE680346A (enrdf_load_stackoverflow) | 1966-10-31 |
| FR4585M (enrdf_load_stackoverflow) | 1966-11-14 |
| FR1455103A (fr) | 1966-04-01 |
| NL6606108A (enrdf_load_stackoverflow) | 1966-11-07 |
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