GB1140872A - 6-demethyl tetracyclines - Google Patents
6-demethyl tetracyclinesInfo
- Publication number
- GB1140872A GB1140872A GB3404068A GB3404068A GB1140872A GB 1140872 A GB1140872 A GB 1140872A GB 3404068 A GB3404068 A GB 3404068A GB 3404068 A GB3404068 A GB 3404068A GB 1140872 A GB1140872 A GB 1140872A
- Authority
- GB
- United Kingdom
- Prior art keywords
- demethyl
- growth factors
- nitrogen
- feb
- earth metal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000004098 Tetracycline Substances 0.000 title abstract 2
- 235000019364 tetracycline Nutrition 0.000 title abstract 2
- 229940040944 tetracyclines Drugs 0.000 title abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical class N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 6
- 239000003102 growth factor Chemical class 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 2
- -1 alkaline earth metal carbonate Chemical class 0.000 abstract 2
- 238000000855 fermentation Methods 0.000 abstract 2
- 230000004151 fermentation Effects 0.000 abstract 2
- 235000015097 nutrients Nutrition 0.000 abstract 2
- RMVMLZHPWMTQGK-SOUFLCLCSA-N (4s,4as,5as,6s,12ar)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1([C@H]2O)=CC=CC(O)=C1C(O)=C1[C@@H]2C[C@H]2[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]2(O)C1=O RMVMLZHPWMTQGK-SOUFLCLCSA-N 0.000 abstract 1
- GUXHBMASAHGULD-SEYHBJAFSA-N (4s,4as,5as,6s,12ar)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1([C@H]2O)=C(Cl)C=CC(O)=C1C(O)=C1[C@@H]2C[C@H]2[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]2(O)C1=O GUXHBMASAHGULD-SEYHBJAFSA-N 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical class [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- FMTDIUIBLCQGJB-UHFFFAOYSA-N Demethylchlortetracyclin Natural products C1C2C(O)C3=C(Cl)C=CC(O)=C3C(=O)C2=C(O)C2(O)C1C(N(C)C)C(O)=C(C(N)=O)C2=O FMTDIUIBLCQGJB-UHFFFAOYSA-N 0.000 abstract 1
- 241000187180 Streptomyces sp. Species 0.000 abstract 1
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000007244 Zea mays Nutrition 0.000 abstract 1
- 239000012190 activator Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 230000023852 carbohydrate metabolic process Effects 0.000 abstract 1
- 235000021256 carbohydrate metabolism Nutrition 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- JCSGAUKCDAVARS-UHFFFAOYSA-N demethyltetracycline Natural products CN(C1C(=C(C(C2(C(=C3C(C4=C(C=CC=C4C(C3CC12)O)O)=O)O)O)=O)C(=O)N)O)C JCSGAUKCDAVARS-UHFFFAOYSA-N 0.000 abstract 1
- BDAGIHXWWSANSR-NJFSPNSNSA-N hydroxyformaldehyde Chemical compound O[14CH]=O BDAGIHXWWSANSR-NJFSPNSNSA-N 0.000 abstract 1
- 229910052500 inorganic mineral Chemical class 0.000 abstract 1
- 235000012054 meals Nutrition 0.000 abstract 1
- 239000011707 mineral Chemical class 0.000 abstract 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 abstract 1
- 235000019796 monopotassium phosphate Nutrition 0.000 abstract 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910000018 strontium carbonate Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT288365 | 1965-02-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1140872A true GB1140872A (en) | 1969-01-22 |
Family
ID=11103465
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3404068A Expired GB1140872A (en) | 1965-02-11 | 1966-02-11 | 6-demethyl tetracyclines |
| GB617466A Expired GB1140871A (en) | 1965-02-11 | 1966-02-11 | Tetracycline |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB617466A Expired GB1140871A (en) | 1965-02-11 | 1966-02-11 | Tetracycline |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE674154A (enrdf_load_html_response) |
| ES (1) | ES322810A1 (enrdf_load_html_response) |
| GB (2) | GB1140872A (enrdf_load_html_response) |
| NL (1) | NL6513122A (enrdf_load_html_response) |
-
0
- BE BE674154D patent/BE674154A/xx unknown
-
1965
- 1965-10-11 NL NL6513122A patent/NL6513122A/xx unknown
-
1966
- 1966-02-09 ES ES0322810A patent/ES322810A1/es not_active Expired
- 1966-02-11 GB GB3404068A patent/GB1140872A/en not_active Expired
- 1966-02-11 GB GB617466A patent/GB1140871A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES322810A1 (es) | 1966-11-16 |
| GB1140871A (en) | 1969-01-22 |
| NL6513122A (enrdf_load_html_response) | 1966-08-12 |
| BE674154A (enrdf_load_html_response) |
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