GB1140872A - 6-demethyl tetracyclines - Google Patents

6-demethyl tetracyclines

Info

Publication number
GB1140872A
GB1140872A GB3404068A GB3404068A GB1140872A GB 1140872 A GB1140872 A GB 1140872A GB 3404068 A GB3404068 A GB 3404068A GB 3404068 A GB3404068 A GB 3404068A GB 1140872 A GB1140872 A GB 1140872A
Authority
GB
United Kingdom
Prior art keywords
demethyl
growth factors
nitrogen
feb
earth metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3404068A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxochem SpA
Original Assignee
Ankerfarm SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ankerfarm SpA filed Critical Ankerfarm SpA
Publication of GB1140872A publication Critical patent/GB1140872A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

1,140,872. 6-Demethyl tetracyclines. ANKERFARM S.p.A. 11 Feb., 1966 [11 Feb., 1965], No. 34040/68. Divided out of 1,140,871. Heading C2A. 6-Demethyl tetracycline and/or 6-demethyl-7- chlorotetracycline is produced by cultivating Streptomyces sp. mutant strain D84 (C.B.S. 322À67) in an aqueous nutrient medium containing assimilable sources of nitrogen, carbon, growth factors, alkaline earth metal carbonate and mineral salts under aerobic conditions. Chrysalid meal may be used as a source of protein nitrogen and growth factors. Strontium carbonate is the preferred alkaline earth metal carbonate. Mycelial fermentation residues may be added as the source of nitrogen and growth factors. Potassium dihydrogen phosphate may be added as an activator of carbohydrate metabolism. The pH is 6À0 to 7À0 and the temperature of cultivation 22 to 34‹ C. Zea mays extract may also be present in the nutrient medium. The antibiotics are recovered from the fermentation broth by conventional methods.
GB3404068A 1965-02-11 1966-02-11 6-demethyl tetracyclines Expired GB1140872A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT288365 1965-02-11

Publications (1)

Publication Number Publication Date
GB1140872A true GB1140872A (en) 1969-01-22

Family

ID=11103465

Family Applications (2)

Application Number Title Priority Date Filing Date
GB3404068A Expired GB1140872A (en) 1965-02-11 1966-02-11 6-demethyl tetracyclines
GB617466A Expired GB1140871A (en) 1965-02-11 1966-02-11 Tetracycline

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB617466A Expired GB1140871A (en) 1965-02-11 1966-02-11 Tetracycline

Country Status (4)

Country Link
BE (1) BE674154A (en)
ES (1) ES322810A1 (en)
GB (2) GB1140872A (en)
NL (1) NL6513122A (en)

Also Published As

Publication number Publication date
ES322810A1 (en) 1966-11-16
GB1140871A (en) 1969-01-22
NL6513122A (en) 1966-08-12
BE674154A (en)

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