ES322810A1 - Tetracycline - Google Patents

Tetracycline

Info

Publication number
ES322810A1
ES322810A1 ES0322810A ES322810A ES322810A1 ES 322810 A1 ES322810 A1 ES 322810A1 ES 0322810 A ES0322810 A ES 0322810A ES 322810 A ES322810 A ES 322810A ES 322810 A1 ES322810 A1 ES 322810A1
Authority
ES
Spain
Prior art keywords
source
growth factors
nitrogen
earth metal
alkaline earth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0322810A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxochem SpA
Original Assignee
Ankerfarm SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ankerfarm SpA filed Critical Ankerfarm SpA
Publication of ES322810A1 publication Critical patent/ES322810A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P29/00Preparation of compounds containing a naphthacene ring system, e.g. tetracycline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Tetracycline is produced by culturing mutant strain Streptomyces sp. T. 2369 (CBS 321-67) in an aqueous nutrient medium containing an assimilable source of nitrogen and growth factors, an assimilable source of carbon, an alkaline earth metal carbonate and mineral salts under aerobic conditions. Preferably an aqueous extract of fresh or ensiled Zea mays is used as a source of protein nitrogen and growth factors. Strontium carbonate is the preferred source of alkaline earth metal carbonate. Mycelial fermentation residues may be added as a source of nitrogen and growth factors. Potassium dihydrogen phosphate may be added as an activator of carbohydrate metabolism. The nutrient medium has a pH of 6À0 to 7À0 and the temperature of fermentation is 22 to 34 C.
ES0322810A 1965-02-11 1966-02-09 Tetracycline Expired ES322810A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT288365 1965-02-11

Publications (1)

Publication Number Publication Date
ES322810A1 true ES322810A1 (en) 1966-11-16

Family

ID=11103465

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0322810A Expired ES322810A1 (en) 1965-02-11 1966-02-09 Tetracycline

Country Status (4)

Country Link
BE (1) BE674154A (en)
ES (1) ES322810A1 (en)
GB (2) GB1140872A (en)
NL (1) NL6513122A (en)

Also Published As

Publication number Publication date
GB1140872A (en) 1969-01-22
GB1140871A (en) 1969-01-22
NL6513122A (en) 1966-08-12
BE674154A (en)

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