GB1140833A - Lincomycin derivatives - Google Patents
Lincomycin derivativesInfo
- Publication number
- GB1140833A GB1140833A GB5298/66A GB529866A GB1140833A GB 1140833 A GB1140833 A GB 1140833A GB 5298/66 A GB5298/66 A GB 5298/66A GB 529866 A GB529866 A GB 529866A GB 1140833 A GB1140833 A GB 1140833A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- acid addition
- halo
- products
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OJMMVQQUTAEWLP-KIDUDLJLSA-N lincomycin Chemical class CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@@H](C)O)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 OJMMVQQUTAEWLP-KIDUDLJLSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 4
- HVLLSGMXQDNUAL-UHFFFAOYSA-N triphenyl phosphite Chemical compound C=1C=CC=CC=1OP(OC=1C=CC=CC=1)OC1=CC=CC=C1 HVLLSGMXQDNUAL-UHFFFAOYSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- -1 diphenyl (p-methoxyphenyl) methyl Chemical group 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N thiocyanic acid Chemical compound SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 abstract 2
- RIOQSEWOXXDEQQ-UHFFFAOYSA-N triphenylphosphine Chemical compound C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 RIOQSEWOXXDEQQ-UHFFFAOYSA-N 0.000 abstract 2
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical group O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 125000001118 alkylidene group Chemical group 0.000 abstract 1
- 229940069428 antacid Drugs 0.000 abstract 1
- 239000003159 antacid agent Substances 0.000 abstract 1
- 230000001458 anti-acid effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 230000003139 buffering effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 150000002440 hydroxy compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000006503 p-nitrobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])* 0.000 abstract 1
- 230000003071 parasitic effect Effects 0.000 abstract 1
- 238000005554 pickling Methods 0.000 abstract 1
- 229920005749 polyurethane resin Polymers 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- PNGLEYLFMHGIQO-UHFFFAOYSA-M sodium;3-(n-ethyl-3-methoxyanilino)-2-hydroxypropane-1-sulfonate;dihydrate Chemical compound O.O.[Na+].[O-]S(=O)(=O)CC(O)CN(CC)C1=CC=CC(OC)=C1 PNGLEYLFMHGIQO-UHFFFAOYSA-M 0.000 abstract 1
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 150000003673 urethanes Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
- C07H15/16—Lincomycin; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/64—Preparation of S-glycosides, e.g. lincomycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cleaning Implements For Floors, Carpets, Furniture, Walls, And The Like (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49898965A | 1965-10-20 | 1965-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1140833A true GB1140833A (en) | 1969-01-22 |
Family
ID=23983333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5298/66A Expired GB1140833A (en) | 1965-10-20 | 1966-02-07 | Lincomycin derivatives |
Country Status (16)
-
1966
- 1966-01-18 IL IL25010A patent/IL25010A/en unknown
- 1966-01-24 YU YU0121/66A patent/YU32778B/xx unknown
- 1966-01-29 DE DE19661795742 patent/DE1795742A1/de active Pending
- 1966-02-01 CH CH133966A patent/CH481073A/de not_active IP Right Cessation
- 1966-02-03 BE BE676202D patent/BE676202A/xx not_active IP Right Cessation
- 1966-02-07 NL NL6601522A patent/NL6601522A/xx unknown
- 1966-02-07 SE SE1530/66A patent/SE300620B/xx unknown
- 1966-02-07 OA OA52346A patent/OA01909A/xx unknown
- 1966-02-07 BR BR176991/66A patent/BR6676991D0/pt unknown
- 1966-02-07 GB GB5298/66A patent/GB1140833A/en not_active Expired
- 1966-02-07 NO NO161594A patent/NO123609B/no unknown
- 1966-02-08 FI FI304/66A patent/FI54487C/fi active
- 1966-02-14 ES ES0323064A patent/ES323064A1/es not_active Expired
- 1966-02-17 AT AT146366A patent/AT277458B/de not_active IP Right Cessation
- 1966-04-22 PL PL1966114201A patent/PL79078B1/pl unknown
- 1966-05-06 FR FR60668A patent/FR5785M/fr not_active Expired
-
1970
- 1970-10-12 NO NO03821/70A patent/NO126318B/no unknown
-
1971
- 1971-11-05 YU YU2796/71A patent/YU33068B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| YU32778B (en) | 1975-08-31 |
| NO123609B (enrdf_load_stackoverflow) | 1971-12-20 |
| FI54487B (fi) | 1978-08-31 |
| PL79078B1 (en) | 1975-06-30 |
| AT277458B (de) | 1969-12-29 |
| YU12166A (en) | 1975-02-28 |
| YU33068B (en) | 1976-03-31 |
| YU279671A (en) | 1975-08-31 |
| BR6676991D0 (pt) | 1973-09-18 |
| NL6601522A (enrdf_load_stackoverflow) | 1967-04-21 |
| FI54487C (fi) | 1978-12-11 |
| BE676202A (enrdf_load_stackoverflow) | 1966-08-08 |
| ES323064A1 (es) | 1966-12-01 |
| FR5785M (enrdf_load_stackoverflow) | 1968-02-12 |
| OA01909A (fr) | 1970-02-04 |
| DE1795742A1 (de) | 1974-05-30 |
| NO126318B (enrdf_load_stackoverflow) | 1973-01-22 |
| CH481073A (de) | 1969-11-15 |
| SE300620B (enrdf_load_stackoverflow) | 1968-05-06 |
| IL25010A (en) | 1971-11-29 |
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