GB1131036A - Device for determining liquid volumes by measurement of the dilution of a radio-active solution - Google Patents
Device for determining liquid volumes by measurement of the dilution of a radio-active solutionInfo
- Publication number
- GB1131036A GB1131036A GB1419766A GB1419766A GB1131036A GB 1131036 A GB1131036 A GB 1131036A GB 1419766 A GB1419766 A GB 1419766A GB 1419766 A GB1419766 A GB 1419766A GB 1131036 A GB1131036 A GB 1131036A
- Authority
- GB
- United Kingdom
- Prior art keywords
- solution
- dilution
- injection
- radio
- volume
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000243 solution Substances 0.000 title abstract 13
- 239000012895 dilution Substances 0.000 title abstract 6
- 238000010790 dilution Methods 0.000 title abstract 6
- 238000005259 measurement Methods 0.000 title abstract 4
- 230000002285 radioactive effect Effects 0.000 title abstract 4
- 239000007788 liquid Substances 0.000 title abstract 2
- 238000002347 injection Methods 0.000 abstract 9
- 239000007924 injection Substances 0.000 abstract 9
- 239000008280 blood Substances 0.000 abstract 7
- 210000004369 blood Anatomy 0.000 abstract 7
- 230000000694 effects Effects 0.000 abstract 7
- 239000013078 crystal Substances 0.000 abstract 4
- 239000003550 marker Substances 0.000 abstract 1
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 abstract 1
- 230000005258 radioactive decay Effects 0.000 abstract 1
- 239000012857 radioactive material Substances 0.000 abstract 1
- 229910052716 thallium Inorganic materials 0.000 abstract 1
- -1 thallium-activated sodium iodide Chemical class 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21H—OBTAINING ENERGY FROM RADIOACTIVE SOURCES; APPLICATIONS OF RADIATION FROM RADIOACTIVE SOURCES, NOT OTHERWISE PROVIDED FOR; UTILISING COSMIC RADIATION
- G21H5/00—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for
- G21H5/02—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for as tracers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/026—Measuring blood flow
- A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
- A61B5/02755—Radioactive tracers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T7/00—Details of radiation-measuring instruments
- G01T7/02—Collecting means for receiving or storing samples to be investigated and possibly directly transporting the samples to the measuring arrangement; particularly for investigating radioactive fluids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- High Energy & Nuclear Physics (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Cardiology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medical Informatics (AREA)
- General Engineering & Computer Science (AREA)
- Physiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
1,131,036. Volume measurement by radioactive solution dilution. COMMISSARIAT A L'ENERGIE ATOMIQUE. March 30, 1966 [March 30, 1965], No. 14197/66. Heading G1A. A liquid volume e. g. the blood volume of a human being, is measured by determining the dilution of a radio-active solution using a photodetector to measure the activities and thereby concentrations of samples before and after the dilution. In the determination of blood volume, the concentration of a radio-active marker in a solution is measured, the solution injected intravenously, and after a certain time, a blood sample taken and its concentration determined and compared with that of the original injection solution. Since the concentration of radio-active material is directly proportional to the volume it is contained in, the total volume of the vascular system into which the injection was made, may be determined. The invention seeks to provide for the great difference between the concentrations, and thus activities, of the blood sample and the original injection solution, but to avoid having to dilute the injection solution before determining its activity and thereby avoid errors due to radio-active decay before the injection can be carried out. The apparatus used comprises a movable tripod 1, carrying a housing 4 containing the detector system, a photo-multiplier 7 and a hollow, thallium-activated sodium iodide scintillation crystal 6. Lead shielding 10 is formed with a pedestal 14 in which a threaded column 12 turns freely on rotation by a wheel 15, causing a threaded nut 17 to move up or down the column. The nut is integral with a support plate 18 for a syringe 20, allowing the latter to be moved to the required distance from the detector system. The distance of the syringe support from the detector is adjusted so that the activity, measured by the detector, of a syringe full of the injection solution, is of the same order as that which will be recorded when a test tube containing a blood sample taken a certain time after the injection, is placed in the bore of the scintillator crystal 6. To obtain this distance a test tube of solution diluted to a known dilution, say 1 in a 1, 000, is placed in the crystal bore and the activity recorded. The same amount of the concentrated solution in a syringe is then positioned in the support plate 18 and the position changed until the same activity is recorded. A series of measurements may then be carried out without dilution of the injection solution beforehand, a first measurement of the injection solution being carried out with the syringe in the support plate and a second of a blood sample carried in a test tube in the crystal bore. The known ratio is taken into account when the activities are compared to calculate the blood volume.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR11188A FR1438431A (en) | 1965-03-30 | 1965-03-30 | Method and device for the determination of liquid volumes by dilution of a radioactive solution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1131036A true GB1131036A (en) | 1968-10-16 |
Family
ID=8575188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1419766A Expired GB1131036A (en) | 1965-03-30 | 1966-03-30 | Device for determining liquid volumes by measurement of the dilution of a radio-active solution |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE677800A (en) |
| CH (1) | CH452912A (en) |
| DE (1) | DE1938908U (en) |
| ES (1) | ES324617A1 (en) |
| FR (1) | FR1438431A (en) |
| GB (1) | GB1131036A (en) |
| LU (1) | LU50773A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996035131A1 (en) * | 1995-05-05 | 1996-11-07 | Capintec, Inc. | Non-invasive radio nuclide detection meter |
| CN109298439A (en) * | 2016-10-26 | 2019-02-01 | 中国疾病预防控制中心辐射防护与核安全医学所 | One kind being based on radiometric rapid detection system |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104786956B (en) * | 2015-04-24 | 2017-06-20 | 安徽宸瑞节能环保科技工程有限公司 | A kind of fixing device for driver's cabin video camera |
-
1965
- 1965-03-30 FR FR11188A patent/FR1438431A/en not_active Expired
-
1966
- 1966-03-14 BE BE677800D patent/BE677800A/xx unknown
- 1966-03-14 CH CH362566A patent/CH452912A/en unknown
- 1966-03-18 DE DE1966C0014307 patent/DE1938908U/en not_active Expired
- 1966-03-24 ES ES324617A patent/ES324617A1/en not_active Expired
- 1966-03-28 LU LU50773A patent/LU50773A1/xx unknown
- 1966-03-30 GB GB1419766A patent/GB1131036A/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996035131A1 (en) * | 1995-05-05 | 1996-11-07 | Capintec, Inc. | Non-invasive radio nuclide detection meter |
| CN109298439A (en) * | 2016-10-26 | 2019-02-01 | 中国疾病预防控制中心辐射防护与核安全医学所 | One kind being based on radiometric rapid detection system |
| CN109298439B (en) * | 2016-10-26 | 2020-03-27 | 中国疾病预防控制中心辐射防护与核安全医学所 | Rapid detection system based on radioactivity measurement |
Also Published As
| Publication number | Publication date |
|---|---|
| CH452912A (en) | 1968-03-15 |
| LU50773A1 (en) | 1966-05-31 |
| BE677800A (en) | 1966-08-01 |
| DE1938908U (en) | 1966-05-18 |
| FR1438431A (en) | 1966-05-13 |
| ES324617A1 (en) | 1968-03-16 |
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| SU155568A1 (en) | MEASUREMENT SCINTILLATION TYPE OF DECISION was made on December 3, 1961 for July 754088 / 26-10c Committee for Inventions and Discoveries under the Council of Ministers of the USSR Published in the Bulletin of Inventions and Trademarks, Lg 13, 1963 wastewaters containing radioactive substances released by industrial enterprises and institutions are of great importance for observing the permissible values established by law. The difficulties of measuring such contaminants are, on the one hand, at low levels of activity), which have to be found near the allowable limit, and, on the other hand, that at the same time: the requirements of continuity of measurements are imposed. ^ In addition, the measured values should be read out without delay, so that you can stop the flow of water in a timely manner. Therefore, the most essential requirements are, for example, the efficiency of radiation, the detection efficiency, primarily for beta and gamma radiation, and also optimum]. geometrical index. To control the radioactivity of water; whether other waste liquids are taken as the basis of the concentration allowed by international conglomerations. A maximum donust is set for the isotopes of the s-isotopes ;; - 10 μ'micro concentration per milliliter. Direct measurement of such a small radioactivity is possible only with the presence !! complex equipment. Bolch'Instvo known measurement methods! requires the enrichment of the active substance, most often by evaporation. In addition, the enrichment method makes it very difficult to create equipment for the production of continuous measurements. Among the methods of enrichment are mainly known: distillation, ion exchange processes and the method of precipitation or adsorption. The disadvantage is the use of distillation for coptitripe radio |