GB1127457A - Carboxylic acid-n-methyl-piperazides and process for their manufacture - Google Patents
Carboxylic acid-n-methyl-piperazides and process for their manufactureInfo
- Publication number
- GB1127457A GB1127457A GB3105/66A GB310566A GB1127457A GB 1127457 A GB1127457 A GB 1127457A GB 3105/66 A GB3105/66 A GB 3105/66A GB 310566 A GB310566 A GB 310566A GB 1127457 A GB1127457 A GB 1127457A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- formula
- compound
- acid
- jan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 3
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 abstract 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- PVOAHINGSUIXLS-UHFFFAOYSA-N 1-Methylpiperazine Chemical compound CN1CCNCC1 PVOAHINGSUIXLS-UHFFFAOYSA-N 0.000 abstract 1
- -1 Acyl N-methylpiperazines Chemical class 0.000 abstract 1
- 239000012670 alkaline solution Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 150000001540 azides Chemical class 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
- JBFYUZGYRGXSFL-UHFFFAOYSA-N imidazolide Chemical compound C1=C[N-]C=N1 JBFYUZGYRGXSFL-UHFFFAOYSA-N 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 239000012022 methylating agents Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 229910052759 nickel Inorganic materials 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229910052763 palladium Inorganic materials 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G9/00—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor
- A23G9/04—Production of frozen sweets, e.g. ice-cream
- A23G9/22—Details, component parts or accessories of apparatus insofar as not peculiar to a single one of the preceding groups
- A23G9/26—Details, component parts or accessories of apparatus insofar as not peculiar to a single one of the preceding groups for producing frozen sweets on sticks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Confectionery (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0045069 | 1965-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1127457A true GB1127457A (en) | 1968-09-18 |
Family
ID=7100329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3105/66A Expired GB1127457A (en) | 1965-01-27 | 1966-01-24 | Carboxylic acid-n-methyl-piperazides and process for their manufacture |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US3373163A (enExample) |
| BE (1) | BE675681A (enExample) |
| CH (1) | CH474526A (enExample) |
| DE (1) | DE1545786A1 (enExample) |
| FR (2) | FR1482082A (enExample) |
| GB (1) | GB1127457A (enExample) |
| MY (1) | MY7000097A (enExample) |
| NL (1) | NL6601067A (enExample) |
| OA (1) | OA02201A (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1545786A1 (de) * | 1965-01-27 | 1969-12-11 | Hoechst Ag | Verfahren zur Herstellung von Carbonsaeure-N-methylpiperaziden |
| BE791501A (fr) * | 1971-11-19 | 1973-05-17 | Albert Ag Chem Werke | Diamines cycliques n,n'-disubstituees et leur procede de preparation |
| US4523014A (en) * | 1983-01-17 | 1985-06-11 | Usv Pharmaceutical Corporation | Piperazines 1-hexyl-4(3-ketohexyl) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT218021B (de) * | 1959-08-21 | 1961-11-10 | Wellcome Found | Verfahren zur Herstellung von neuen Piperazinverbindungen |
| US3147261A (en) * | 1962-05-24 | 1964-09-01 | Robert R Mod | Nu-acyl-nu'-methylpiperazines |
| DE1545786A1 (de) * | 1965-01-27 | 1969-12-11 | Hoechst Ag | Verfahren zur Herstellung von Carbonsaeure-N-methylpiperaziden |
-
1965
- 1965-01-27 DE DE19651545786 patent/DE1545786A1/de active Pending
-
1966
- 1966-01-18 US US521445A patent/US3373163A/en not_active Expired - Lifetime
- 1966-01-24 CH CH90266A patent/CH474526A/de not_active IP Right Cessation
- 1966-01-24 GB GB3105/66A patent/GB1127457A/en not_active Expired
- 1966-01-27 BE BE675681D patent/BE675681A/xx unknown
- 1966-01-27 NL NL6601067A patent/NL6601067A/xx unknown
- 1966-01-27 OA OA52336A patent/OA02201A/xx unknown
- 1966-03-16 FR FR47065A patent/FR1482082A/fr not_active Expired
- 1966-04-26 FR FR59099A patent/FR5444M/fr not_active Expired
-
1967
- 1967-06-23 US US655709A patent/US3484524A/en not_active Expired - Lifetime
-
1970
- 1970-12-31 MY MY197097A patent/MY7000097A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR1482082A (fr) | 1967-05-26 |
| CH474526A (de) | 1969-06-30 |
| NL6601067A (enExample) | 1966-07-28 |
| DE1545786A1 (de) | 1969-12-11 |
| BE675681A (enExample) | 1966-07-27 |
| OA02201A (fr) | 1970-05-05 |
| MY7000097A (en) | 1970-12-31 |
| FR5444M (enExample) | 1967-10-09 |
| US3484524A (en) | 1969-12-16 |
| US3373163A (en) | 1968-03-12 |
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