GB1126579A - Continuous production of glutamic acid by fermentation - Google Patents

Continuous production of glutamic acid by fermentation

Info

Publication number
GB1126579A
GB1126579A GB5327565A GB5327565A GB1126579A GB 1126579 A GB1126579 A GB 1126579A GB 5327565 A GB5327565 A GB 5327565A GB 5327565 A GB5327565 A GB 5327565A GB 1126579 A GB1126579 A GB 1126579A
Authority
GB
United Kingdom
Prior art keywords
glutamic acid
growth
vessel
medium
stage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5327565A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US514758A external-priority patent/US3402104A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1126579A publication Critical patent/GB1126579A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

1,126,579. Glutamic acid. MERCK & CO. Inc. 15 Dec., 1965 [5 Jan., 1965; 29 Nov., 1965], No. 53275/65. Heading C2C. A continuous method for the production of L-glutamic acid uses two or three vessels placed in series relationship. The first vessel is used as a growth-stage vessel in which biotinrequiring strains of L-glutamic acid-producing micro-organisms are grown at a constant rate on a continuously replenished medium containing biotin or a precursor or analogue thereof having similar growth promoting properties. Culture broth from the first vessel is fed at a constant rate to a production stage vessel or successively to transition and production stage vessels where growth inhibiting conditions are applied either by deplenishment of nutrient medium or by simultaneous introduction of growth inhibitor along with further nutrient medium. Continuous aeration and agitation are also applied at this stage and growth-inhibited culture medium is continuously withdrawn and L-glutamic acid or a salt thereof is recovered from said medium.
GB5327565A 1965-01-05 1965-12-15 Continuous production of glutamic acid by fermentation Expired GB1126579A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42350365A 1965-01-05 1965-01-05
US514758A US3402104A (en) 1965-11-29 1965-11-29 Continuous fermentation of glutamic acid

Publications (1)

Publication Number Publication Date
GB1126579A true GB1126579A (en) 1968-09-05

Family

ID=27026025

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5327565A Expired GB1126579A (en) 1965-01-05 1965-12-15 Continuous production of glutamic acid by fermentation

Country Status (3)

Country Link
CH (1) CH488012A (en)
FR (1) FR1469233A (en)
GB (1) GB1126579A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2147580A (en) * 1983-08-05 1985-05-15 Grace W R & Co Improved process for producing L-amino acids from alpha-keto acids by fed-batch fermentation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2147580A (en) * 1983-08-05 1985-05-15 Grace W R & Co Improved process for producing L-amino acids from alpha-keto acids by fed-batch fermentation

Also Published As

Publication number Publication date
CH488012A (en) 1970-03-31
FR1469233A (en) 1967-02-10

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