GB1122919A - Benzenesulphonyl-ureas and process for preparing them - Google Patents
Benzenesulphonyl-ureas and process for preparing themInfo
- Publication number
- GB1122919A GB1122919A GB29735/66A GB2973566A GB1122919A GB 1122919 A GB1122919 A GB 1122919A GB 29735/66 A GB29735/66 A GB 29735/66A GB 2973566 A GB2973566 A GB 2973566A GB 1122919 A GB1122919 A GB 1122919A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lower alkyl
- benzenesulphonyl
- atom
- urea
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- -1 phenylcyclopropyl Chemical group 0.000 abstract 6
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 4
- 239000004202 carbamide Substances 0.000 abstract 3
- 235000013877 carbamide Nutrition 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004434 sulfur atom Chemical group 0.000 abstract 2
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- KHBQMWCZKVMBLN-UHFFFAOYSA-N Benzenesulfonamide Chemical class NS(=O)(=O)C1=CC=CC=C1 KHBQMWCZKVMBLN-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- NHYNLEOHVUHVEG-UHFFFAOYSA-N S=NC(=O)N.C1=CC=CC=C1 Chemical compound S=NC(=O)N.C1=CC=CC=C1 NHYNLEOHVUHVEG-UHFFFAOYSA-N 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- NNHSFBDNDJBVBD-UHFFFAOYSA-N benzenesulfinylurea Chemical compound NC(=O)NS(=O)C1=CC=CC=C1 NNHSFBDNDJBVBD-UHFFFAOYSA-N 0.000 abstract 1
- PVMBGVAQRSHDBB-UHFFFAOYSA-N benzenesulfonylthiourea Chemical class NC(=S)NS(=O)(=O)C1=CC=CC=C1 PVMBGVAQRSHDBB-UHFFFAOYSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 150000001714 carbamic acid halides Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000006622 cycloheptylmethyl group Chemical group 0.000 abstract 1
- 125000000596 cyclohexenyl group Chemical group C1(=CCCCC1)* 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000006623 cyclooctylmethyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000002218 hypoglycaemic effect Effects 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 125000005358 mercaptoalkyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- UJYAZVSPFMJCLW-UHFFFAOYSA-N n-(oxomethylidene)benzenesulfonamide Chemical class O=C=NS(=O)(=O)C1=CC=CC=C1 UJYAZVSPFMJCLW-UHFFFAOYSA-N 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- ZFLIKDUSUDBGCD-UHFFFAOYSA-N parabanic acid Chemical compound O=C1NC(=O)C(=O)N1 ZFLIKDUSUDBGCD-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 1
- KJAMZCVTJDTESW-UHFFFAOYSA-N tiracizine Chemical class C1CC2=CC=CC=C2N(C(=O)CN(C)C)C2=CC(NC(=O)OCC)=CC=C21 KJAMZCVTJDTESW-UHFFFAOYSA-N 0.000 abstract 1
- 150000003672 ureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0046641 | 1965-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1122919A true GB1122919A (en) | 1968-08-07 |
Family
ID=7101153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB29735/66A Expired GB1122919A (en) | 1965-07-17 | 1966-07-01 | Benzenesulphonyl-ureas and process for preparing them |
Country Status (20)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016522831A (ja) | 2013-05-21 | 2016-08-04 | ヴァージニア コモンウェルス ユニバーシティ | 炎症を予防および治療するためのクリオピリン阻害剤 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1157211B (de) * | 1961-07-28 | 1963-11-14 | Hoechst Ag | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
-
1965
- 1965-07-17 DE DE1518846A patent/DE1518846C3/de not_active Expired
-
1966
- 1966-04-29 IL IL25664A patent/IL25664A/xx unknown
- 1966-05-09 NO NO162926A patent/NO123644B/no unknown
- 1966-05-31 US US553624A patent/US3489798A/en not_active Expired - Lifetime
- 1966-06-01 MC MC625A patent/MC599A1/xx unknown
- 1966-06-02 FI FI661452A patent/FI45958C/fi active
- 1966-06-16 BR BR180469/66A patent/BR6680469D0/pt unknown
- 1966-06-30 OA OA52501A patent/OA02086A/xx unknown
- 1966-06-30 FR FR67660A patent/FR5522M/fr not_active Expired
- 1966-07-01 GB GB29735/66A patent/GB1122919A/en not_active Expired
- 1966-07-12 NL NL666609759A patent/NL149160B/xx unknown
- 1966-07-13 DK DK364566AA patent/DK120127B/da unknown
- 1966-07-14 CH CH1021366A patent/CH475215A/de not_active IP Right Cessation
- 1966-07-14 SE SE09664/66A patent/SE338984B/xx unknown
- 1966-07-14 ES ES0329118A patent/ES329118A1/es not_active Expired
- 1966-07-14 LU LU51564D patent/LU51564A1/xx unknown
- 1966-07-15 AT AT576268A patent/AT272366B/de active
- 1966-07-15 AT AT576168A patent/AT272365B/de active
- 1966-07-15 AT AT576068A patent/AT272364B/de active
- 1966-07-15 AT AT680966A patent/AT272361B/de active
- 1966-07-15 AT AT576468A patent/AT272368B/de active
- 1966-07-15 AT AT576368A patent/AT272367B/de active
- 1966-07-18 BE BE684269D patent/BE684269A/xx unknown
-
1967
- 1967-04-12 ES ES339206A patent/ES339206A1/es not_active Expired
-
1970
- 1970-04-21 CY CY53770A patent/CY537A/xx unknown
- 1970-12-31 MY MY197096A patent/MY7000096A/xx unknown
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