GB1122153A - Low temperature resistant aerosol anesthetic preparation - Google Patents
Low temperature resistant aerosol anesthetic preparationInfo
- Publication number
- GB1122153A GB1122153A GB2713/67A GB271367A GB1122153A GB 1122153 A GB1122153 A GB 1122153A GB 2713/67 A GB2713/67 A GB 2713/67A GB 271367 A GB271367 A GB 271367A GB 1122153 A GB1122153 A GB 1122153A
- Authority
- GB
- United Kingdom
- Prior art keywords
- propellant
- low temperature
- solvent
- temperature resistant
- resistant aerosol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K3/00—Materials not provided for elsewhere
- C09K3/30—Materials not provided for elsewhere for aerosols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
An aerosol local anaesthetic composition comprises at least 10% w./w. benzocaine in a polyethylene glycol diester solvent, at least 90% by weight of which is esters of the general formula R.COO(CH2CH2.O)n.OOCR1, where R and R1 are C7- 11 alkyl groups and n is an integer from 7 to 15, together with a propellant which is dichlorodifluoromethane or a mixture thereof with up to 30% trichlorofluoromethane, there being at least 1.5 parts of propellant per part of solvent.ALSO:An aerosol local anaesthetic composition comprises benzocaine (at least 10% w/w) dissolved in a polyethylene glycol diester solvent, at least 90% by weight of which is composed of esters of the general formula: R.COO (CH2.CH2.O)n OOC.R1 where R and R1 are C7-11 alkyl groups and n is an integer from 7-15, together with a propellant which is dichlorodifluoromethane or a mixture thereof with up to 30% trichlorofluoromethane, there being at least 1.5 parts of propellant per part of solvent.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38094564A | 1964-07-07 | 1964-07-07 | |
US400949A US3322624A (en) | 1964-07-07 | 1964-10-01 | Low temperature resistant aerosol anesthetic preparation containing benzocaine |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1122153A true GB1122153A (en) | 1968-07-31 |
Family
ID=27009179
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2713/67A Expired GB1122153A (en) | 1964-07-07 | 1967-01-18 | Low temperature resistant aerosol anesthetic preparation |
Country Status (4)
Country | Link |
---|---|
US (1) | US3322624A (en) |
CH (1) | CH478083A (en) |
DE (1) | DE1617292A1 (en) |
GB (1) | GB1122153A (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4052513A (en) * | 1974-12-13 | 1977-10-04 | Plough, Inc. | Stable topical anesthetic compositions |
US4344965A (en) * | 1978-10-13 | 1982-08-17 | Raymond Stone | Anesthetic compositions containing benzocaine |
US4600575A (en) * | 1979-03-08 | 1986-07-15 | American Home Products Corporation | Aerosol anesthetic compositions |
US4241048A (en) * | 1979-05-01 | 1980-12-23 | Bristol-Myers Company | Suspension composition of benzocaine |
US4935225A (en) * | 1987-09-11 | 1990-06-19 | Curtis John P | Appetite suppresant dentifrice |
US5558914A (en) * | 1994-04-11 | 1996-09-24 | Water-Jel Technologies, Inc. | Water-based formulation for the treatment of sunburn |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2457188A (en) * | 1945-05-24 | 1948-12-28 | Americaine Inc | Benzocaine solution |
US2713019A (en) * | 1951-01-31 | 1955-07-12 | Allied Lab Inc | Antibiotic pharmaceutical preparation containing polyethylene glycol diester as vehicle |
US2801201A (en) * | 1953-04-09 | 1957-07-30 | Lincoln Lab Inc | Burn treatment filling for pressure packaged dispenser |
-
1964
- 1964-10-01 US US400949A patent/US3322624A/en not_active Expired - Lifetime
-
1967
- 1967-01-18 GB GB2713/67A patent/GB1122153A/en not_active Expired
- 1967-05-29 CH CH754567A patent/CH478083A/en not_active IP Right Cessation
- 1967-05-30 DE DE19671617292 patent/DE1617292A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US3322624A (en) | 1967-05-30 |
CH478083A (en) | 1969-09-15 |
DE1617292A1 (en) | 1971-02-18 |
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