GB1118930A - A method of making peptides - Google Patents
A method of making peptidesInfo
- Publication number
- GB1118930A GB1118930A GB27085/65A GB2708565A GB1118930A GB 1118930 A GB1118930 A GB 1118930A GB 27085/65 A GB27085/65 A GB 27085/65A GB 2708565 A GB2708565 A GB 2708565A GB 1118930 A GB1118930 A GB 1118930A
- Authority
- GB
- United Kingdom
- Prior art keywords
- enzyme
- soln
- ppt
- dialysing
- apo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 abstract 4
- 102000004190 Enzymes Human genes 0.000 abstract 4
- 239000000463 material Substances 0.000 abstract 3
- 108010006591 Apoenzymes Proteins 0.000 abstract 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 abstract 2
- 229910052921 ammonium sulfate Inorganic materials 0.000 abstract 2
- 235000011130 ammonium sulphate Nutrition 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 244000309466 calf Species 0.000 abstract 2
- 238000005342 ion exchange Methods 0.000 abstract 2
- 210000004185 liver Anatomy 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- JVIPLYCGEZUBIO-UHFFFAOYSA-N 2-(4-fluorophenyl)-1,3-dioxoisoindole-5-carboxylic acid Chemical compound O=C1C2=CC(C(=O)O)=CC=C2C(=O)N1C1=CC=C(F)C=C1 JVIPLYCGEZUBIO-UHFFFAOYSA-N 0.000 abstract 1
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 abstract 1
- 229920001425 Diethylaminoethyl cellulose Polymers 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 150000001371 alpha-amino acids Chemical class 0.000 abstract 1
- 235000008206 alpha-amino acids Nutrition 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 229910001425 magnesium ion Inorganic materials 0.000 abstract 1
- LWJROJCJINYWOX-UHFFFAOYSA-L mercury dichloride Chemical compound Cl[Hg]Cl LWJROJCJINYWOX-UHFFFAOYSA-L 0.000 abstract 1
- 239000008363 phosphate buffer Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- KOUKXHPPRFNWPP-UHFFFAOYSA-N pyrazine-2,5-dicarboxylic acid;hydrate Chemical compound O.OC(=O)C1=CN=C(C(O)=O)C=N1 KOUKXHPPRFNWPP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/695—Corticotropin [ACTH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Drying Of Solid Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE08164/64A SE333935B (https=) | 1964-07-03 | 1964-07-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1118930A true GB1118930A (en) | 1968-07-03 |
Family
ID=20273322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB27085/65A Expired GB1118930A (en) | 1964-07-03 | 1965-06-25 | A method of making peptides |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3544426A (https=) |
| AT (1) | AT278257B (https=) |
| BE (1) | BE666343A (https=) |
| CH (1) | CH493472A (https=) |
| DE (1) | DE1518316A1 (https=) |
| GB (1) | GB1118930A (https=) |
| IL (1) | IL23790A (https=) |
| NL (1) | NL6508512A (https=) |
| NO (1) | NO118922B (https=) |
| SE (1) | SE333935B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3972773A (en) * | 1975-04-29 | 1976-08-03 | Sagami Chemical Research Center | Process for producing peptide |
| DE3361649D1 (en) * | 1982-01-26 | 1986-02-13 | Imahori Kazutomo | Process for synthesizing peptides or peptide derivatives |
| US5366862A (en) * | 1990-02-14 | 1994-11-22 | Receptor Laboratories, Inc. | Method for generating and screening useful peptides |
-
1964
- 1964-07-03 SE SE08164/64A patent/SE333935B/xx unknown
-
1965
- 1965-06-22 AT AT563065A patent/AT278257B/de not_active IP Right Cessation
- 1965-06-22 NO NO65158619A patent/NO118922B/no unknown
- 1965-06-23 IL IL6523790A patent/IL23790A/xx unknown
- 1965-06-25 GB GB27085/65A patent/GB1118930A/en not_active Expired
- 1965-06-28 DE DE19651518316 patent/DE1518316A1/de active Pending
- 1965-07-01 CH CH919765A patent/CH493472A/de not_active IP Right Cessation
- 1965-07-02 NL NL6508512A patent/NL6508512A/xx unknown
- 1965-07-02 BE BE666343D patent/BE666343A/xx unknown
-
1968
- 1968-09-23 US US766369A patent/US3544426A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO118922B (https=) | 1970-03-02 |
| AT278257B (de) | 1970-01-26 |
| US3544426A (en) | 1970-12-01 |
| DE1518316A1 (de) | 1972-04-13 |
| CH493472A (de) | 1970-07-15 |
| NL6508512A (https=) | 1966-01-04 |
| BE666343A (https=) | 1965-11-03 |
| SE333935B (https=) | 1971-04-05 |
| IL23790A (en) | 1969-11-12 |
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