GB1101158A - Improvements in or relating to the preparation of 3,5-disubstituted isoxazole derivatives - Google Patents
Improvements in or relating to the preparation of 3,5-disubstituted isoxazole derivativesInfo
- Publication number
- GB1101158A GB1101158A GB48081/65A GB4808165A GB1101158A GB 1101158 A GB1101158 A GB 1101158A GB 48081/65 A GB48081/65 A GB 48081/65A GB 4808165 A GB4808165 A GB 4808165A GB 1101158 A GB1101158 A GB 1101158A
- Authority
- GB
- United Kingdom
- Prior art keywords
- relating
- preparation
- isoxazole derivatives
- alkyl
- isoxazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Isoxazole derivatives of general formula <FORM:1101158/C2/1> wherein the 4-position is unsubstituted, R is phenyl optionally substituted by, e.g. C1- 5 alkyl, C1- 5 alkoxy or halogen, R1 and R11 are each H or C1- 5 alkyl or N.R1.R11 is a 5 t 7 membered monocylic saturated heterocyclic ring which may contain a further oxygen nitrogen or sulphur atom, are prepared by reacting an isoxazole of formula <FORM:1101158/C2/2> with formaldehyde and an amine HN.R1.R11. The products may be converted into acid addition salts.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6564964 | 1964-11-20 | ||
JP5095665 | 1965-08-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1101158A true GB1101158A (en) | 1968-01-31 |
Family
ID=26391453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB48081/65A Expired GB1101158A (en) | 1964-11-20 | 1965-11-12 | Improvements in or relating to the preparation of 3,5-disubstituted isoxazole derivatives |
Country Status (9)
Country | Link |
---|---|
BR (1) | BR6575006D0 (en) |
CH (1) | CH472420A (en) |
DE (1) | DE1620324A1 (en) |
DK (2) | DK124614B (en) |
FR (1) | FR4869M (en) |
GB (1) | GB1101158A (en) |
NL (1) | NL148052B (en) |
NO (1) | NO116120B (en) |
SE (1) | SE336337B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6034546B2 (en) * | 1978-03-09 | 1985-08-09 | 大鵬薬品工業株式会社 | Glyoxal-2-oxime derivative and method for producing the same |
US4912120A (en) * | 1986-03-14 | 1990-03-27 | Syntex (U.S.A.) Inc. | 3,5-substituted 4,5-dihydroisoxazoles as transglutaminase inhibitors |
US4929630A (en) * | 1986-03-14 | 1990-05-29 | Syntex (U.S.A.) Inc. | Transglutaminase inhibitors |
-
1965
- 1965-11-12 GB GB48081/65A patent/GB1101158A/en not_active Expired
- 1965-11-16 NO NO16050065A patent/NO116120B/no unknown
- 1965-11-19 DE DE19651620324 patent/DE1620324A1/en active Pending
- 1965-11-19 CH CH1596065A patent/CH472420A/en not_active IP Right Cessation
- 1965-11-19 FR FR39058A patent/FR4869M/fr not_active Expired
- 1965-11-19 SE SE1498665A patent/SE336337B/xx unknown
- 1965-11-19 BR BR17500665A patent/BR6575006D0/en unknown
- 1965-11-20 DK DK597065A patent/DK124614B/en unknown
- 1965-11-22 NL NL656515145A patent/NL148052B/en unknown
-
1966
- 1966-09-21 DK DK48666A patent/DK114061B/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE1620324A1 (en) | 1970-03-19 |
SE336337B (en) | 1971-07-05 |
BR6575006D0 (en) | 1973-09-06 |
CH472420A (en) | 1969-05-15 |
DK114061B (en) | 1969-05-27 |
NL6515145A (en) | 1966-05-23 |
FR4869M (en) | 1967-02-27 |
NO116120B (en) | 1969-02-03 |
DK124614B (en) | 1972-11-06 |
NL148052B (en) | 1975-12-15 |
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