GB1101158A - Improvements in or relating to the preparation of 3,5-disubstituted isoxazole derivatives - Google Patents

Improvements in or relating to the preparation of 3,5-disubstituted isoxazole derivatives

Info

Publication number
GB1101158A
GB1101158A GB48081/65A GB4808165A GB1101158A GB 1101158 A GB1101158 A GB 1101158A GB 48081/65 A GB48081/65 A GB 48081/65A GB 4808165 A GB4808165 A GB 4808165A GB 1101158 A GB1101158 A GB 1101158A
Authority
GB
United Kingdom
Prior art keywords
relating
preparation
isoxazole derivatives
alkyl
isoxazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB48081/65A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of GB1101158A publication Critical patent/GB1101158A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Isoxazole derivatives of general formula <FORM:1101158/C2/1> wherein the 4-position is unsubstituted, R is phenyl optionally substituted by, e.g. C1- 5 alkyl, C1- 5 alkoxy or halogen, R1 and R11 are each H or C1- 5 alkyl or N.R1.R11 is a 5 t 7 membered monocylic saturated heterocyclic ring which may contain a further oxygen nitrogen or sulphur atom, are prepared by reacting an isoxazole of formula <FORM:1101158/C2/2> with formaldehyde and an amine HN.R1.R11. The products may be converted into acid addition salts.
GB48081/65A 1964-11-20 1965-11-12 Improvements in or relating to the preparation of 3,5-disubstituted isoxazole derivatives Expired GB1101158A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6564964 1964-11-20
JP5095665 1965-08-20

Publications (1)

Publication Number Publication Date
GB1101158A true GB1101158A (en) 1968-01-31

Family

ID=26391453

Family Applications (1)

Application Number Title Priority Date Filing Date
GB48081/65A Expired GB1101158A (en) 1964-11-20 1965-11-12 Improvements in or relating to the preparation of 3,5-disubstituted isoxazole derivatives

Country Status (9)

Country Link
BR (1) BR6575006D0 (en)
CH (1) CH472420A (en)
DE (1) DE1620324A1 (en)
DK (2) DK124614B (en)
FR (1) FR4869M (en)
GB (1) GB1101158A (en)
NL (1) NL148052B (en)
NO (1) NO116120B (en)
SE (1) SE336337B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6034546B2 (en) * 1978-03-09 1985-08-09 大鵬薬品工業株式会社 Glyoxal-2-oxime derivative and method for producing the same
US4912120A (en) * 1986-03-14 1990-03-27 Syntex (U.S.A.) Inc. 3,5-substituted 4,5-dihydroisoxazoles as transglutaminase inhibitors
US4929630A (en) * 1986-03-14 1990-05-29 Syntex (U.S.A.) Inc. Transglutaminase inhibitors

Also Published As

Publication number Publication date
DE1620324A1 (en) 1970-03-19
SE336337B (en) 1971-07-05
BR6575006D0 (en) 1973-09-06
CH472420A (en) 1969-05-15
DK114061B (en) 1969-05-27
NL6515145A (en) 1966-05-23
FR4869M (en) 1967-02-27
NO116120B (en) 1969-02-03
DK124614B (en) 1972-11-06
NL148052B (en) 1975-12-15

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