GB1097720A - Method of preparing new iodinated x-ray contrast agent - Google Patents
Method of preparing new iodinated x-ray contrast agentInfo
- Publication number
- GB1097720A GB1097720A GB54229/65A GB5422965A GB1097720A GB 1097720 A GB1097720 A GB 1097720A GB 54229/65 A GB54229/65 A GB 54229/65A GB 5422965 A GB5422965 A GB 5422965A GB 1097720 A GB1097720 A GB 1097720A
- Authority
- GB
- United Kingdom
- Prior art keywords
- triodo
- ray contrast
- contrast agent
- preparing new
- benzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002872 contrast media Substances 0.000 title abstract 2
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 abstract 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- 229910020667 PBr3 Inorganic materials 0.000 abstract 1
- 229910006124 SOCl2 Inorganic materials 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 235000019445 benzyl alcohol Nutrition 0.000 abstract 1
- 229940073608 benzyl chloride Drugs 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- IPNPIHIZVLFAFP-UHFFFAOYSA-N phosphorus tribromide Chemical compound BrP(Br)Br IPNPIHIZVLFAFP-UHFFFAOYSA-N 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nozzles (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS723264 | 1964-12-21 | ||
| CS723364 | 1964-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1097720A true GB1097720A (en) | 1968-01-03 |
Family
ID=25746465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB54229/65A Expired GB1097720A (en) | 1964-12-21 | 1965-12-21 | Method of preparing new iodinated x-ray contrast agent |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3404143A (OSRAM) |
| BE (1) | BE673977A (OSRAM) |
| CH (1) | CH458327A (OSRAM) |
| DE (1) | DE1493136A1 (OSRAM) |
| FR (2) | FR1475702A (OSRAM) |
| GB (1) | GB1097720A (OSRAM) |
| NL (1) | NL6516673A (OSRAM) |
| NO (1) | NO117074B (OSRAM) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3544585A (en) * | 1967-10-04 | 1970-12-01 | Abbott Lab | N'-(4-(hydroxymethyl)-5-pyrazolyl) amidines |
| US4335203A (en) * | 1980-07-10 | 1982-06-15 | The Regents Of The University Of California | Method for identifying potential contrast media reactors |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2552242A (en) * | 1948-03-06 | 1951-05-08 | Eastman Kodak Co | p-phenylenediamines containing n-alkylacetamido ethyl substituent |
| US3227760A (en) * | 1962-07-10 | 1966-01-04 | Velsicol Chemical Corp | N,n-mono- and di-substituted-aralkyl amines |
| DE1189553B (de) * | 1962-08-09 | 1965-03-25 | Degussa | Verfahren zur Herstellung von racemischen und optisch aktiven Piperazinderivaten |
-
1965
- 1965-12-16 NO NO160928A patent/NO117074B/no unknown
- 1965-12-17 BE BE673977D patent/BE673977A/xx unknown
- 1965-12-17 US US514694A patent/US3404143A/en not_active Expired - Lifetime
- 1965-12-17 CH CH1744965A patent/CH458327A/de unknown
- 1965-12-20 DE DE19651493136 patent/DE1493136A1/de active Pending
- 1965-12-21 FR FR43219A patent/FR1475702A/fr not_active Expired
- 1965-12-21 NL NL6516673A patent/NL6516673A/xx unknown
- 1965-12-21 GB GB54229/65A patent/GB1097720A/en not_active Expired
- 1965-12-21 FR FR43220A patent/FR6993M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR1475702A (fr) | 1967-04-07 |
| NO117074B (OSRAM) | 1969-06-30 |
| CH458327A (de) | 1968-06-30 |
| BE673977A (OSRAM) | 1966-04-15 |
| FR6993M (OSRAM) | 1969-06-02 |
| US3404143A (en) | 1968-10-01 |
| NL6516673A (OSRAM) | 1966-06-22 |
| DE1493136A1 (de) | 1969-08-07 |
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