GB1093937A - Betaines of lysine - Google Patents

Betaines of lysine

Info

Publication number
GB1093937A
GB1093937A GB47166/64A GB4716664A GB1093937A GB 1093937 A GB1093937 A GB 1093937A GB 47166/64 A GB47166/64 A GB 47166/64A GB 4716664 A GB4716664 A GB 4716664A GB 1093937 A GB1093937 A GB 1093937A
Authority
GB
United Kingdom
Prior art keywords
reacting
acid
residue
lysine
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB47166/64A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of GB1093937A publication Critical patent/GB1093937A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises (1) novel compounds of formulae <FORM:1093937/C2/1> <FORM:1093937/C2/2> wherein each of R1, R2 and R3 is an alkyl radical having up to 4 carbon atoms, and X is a citric acid, a nicotinic acid residue, an N-acetyl-L-asparagine residue, bromide, iodide, or a carboxylic type cation-exchange residue, and (2) the preparation of compounds of Formula I and salts thereof by reacting copper cations with lysine or its acid addition salt to yield a chelate of formula <FORM:1093937/C2/3> and reacting this compound with an alkylating agent, and, if desired, reacting the compound obtained with an acid or an acidic cation-exchange resin to form an acid addition salt. Reference has been directed by the Comptroller to Specification 865,157.
GB47166/64A 1963-11-22 1964-11-19 Betaines of lysine Expired GB1093937A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6283463 1963-11-22

Publications (1)

Publication Number Publication Date
GB1093937A true GB1093937A (en) 1967-12-06

Family

ID=13211727

Family Applications (1)

Application Number Title Priority Date Filing Date
GB47166/64A Expired GB1093937A (en) 1963-11-22 1964-11-19 Betaines of lysine

Country Status (2)

Country Link
FR (1) FR4235M (en)
GB (1) GB1093937A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0127098A2 (en) * 1983-05-25 1984-12-05 Takeda Chemical Industries, Ltd. Derivatives of beta-amino-gamma-trimethylammonio-butyrate, their production and use
US4521432A (en) * 1981-11-26 1985-06-04 Takeda Chemical Industries, Ltd. Physiologically active substance FA-5859, its derivative, their production and use
WO1985004396A1 (en) * 1984-04-02 1985-10-10 Cornell Research Foundation, Inc. Aminocarnitines
US4767781A (en) * 1981-11-26 1988-08-30 Takeda Chemical Industries, Ltd. Derivatives of beta-amino-gamma-trimethylammonio-butyrate and their production and use

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU174503B (en) * 1977-10-13 1980-01-28 Richter Gedeon Vegyeszet Process for producing new n-e-trimethyl-l-lisine salts

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4521432A (en) * 1981-11-26 1985-06-04 Takeda Chemical Industries, Ltd. Physiologically active substance FA-5859, its derivative, their production and use
US4767781A (en) * 1981-11-26 1988-08-30 Takeda Chemical Industries, Ltd. Derivatives of beta-amino-gamma-trimethylammonio-butyrate and their production and use
EP0127098A2 (en) * 1983-05-25 1984-12-05 Takeda Chemical Industries, Ltd. Derivatives of beta-amino-gamma-trimethylammonio-butyrate, their production and use
EP0127098A3 (en) * 1983-05-25 1985-05-29 Takeda Chemical Industries, Ltd. Derivatives of beta-amino-gamma-trimethylammonio-butyrate, their production and use
WO1985004396A1 (en) * 1984-04-02 1985-10-10 Cornell Research Foundation, Inc. Aminocarnitines
AU570112B2 (en) * 1984-04-02 1988-03-03 Cornell Research Foundation Inc. Aminocarnitines

Also Published As

Publication number Publication date
FR4235M (en) 1966-06-20

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