GB1079520A - Novel tetrahydro-isoquinoline derivatives and a process for the manufacture thereof - Google Patents

Novel tetrahydro-isoquinoline derivatives and a process for the manufacture thereof

Info

Publication number
GB1079520A
GB1079520A GB30549/65A GB3054965A GB1079520A GB 1079520 A GB1079520 A GB 1079520A GB 30549/65 A GB30549/65 A GB 30549/65A GB 3054965 A GB3054965 A GB 3054965A GB 1079520 A GB1079520 A GB 1079520A
Authority
GB
United Kingdom
Prior art keywords
group
alkyl
acid addition
together form
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB30549/65A
Other languages
English (en)
Inventor
John Mervyn Osbond
Graham Alwyn Fothergill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Products Ltd
Original Assignee
Roche Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Products Ltd filed Critical Roche Products Ltd
Priority to GB30549/65A priority Critical patent/GB1079520A/en
Priority to CH1597868A priority patent/CH477444A/de
Priority to CH919866A priority patent/CH464922A/de
Priority to IL26040A priority patent/IL26040A/en
Priority to DE19661695147 priority patent/DE1695147A1/de
Priority to US563396A priority patent/US3450704A/en
Priority to BR181255/66A priority patent/BR6681255D0/pt
Priority to BE684185D priority patent/BE684185A/xx
Priority to ES0329218A priority patent/ES329218A1/es
Priority to NL6610093A priority patent/NL6610093A/xx
Priority to DK373466AA priority patent/DK117704B/da
Priority to FR69810A priority patent/FR5796M/fr
Publication of GB1079520A publication Critical patent/GB1079520A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB30549/65A 1965-07-19 1965-07-19 Novel tetrahydro-isoquinoline derivatives and a process for the manufacture thereof Expired GB1079520A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
GB30549/65A GB1079520A (en) 1965-07-19 1965-07-19 Novel tetrahydro-isoquinoline derivatives and a process for the manufacture thereof
CH1597868A CH477444A (de) 1965-07-19 1966-06-24 Verfahren zur Herstellung von Tetrahydroisochinolinderivaten
CH919866A CH464922A (de) 1965-07-19 1966-06-24 Verfahren zur Herstellung von Tetrahydroisochinolinderivaten
IL26040A IL26040A (en) 1965-07-19 1966-06-27 Tetrahydroisoquinoline derivatives and process for the manufacture thereof
DE19661695147 DE1695147A1 (de) 1965-07-19 1966-06-28 Verfahren zur Herstellung von Tetrahydroisochinolinderivaten
US563396A US3450704A (en) 1965-07-19 1966-07-07 Substituted 2 - (3 - aryl - 3 - keto (or 3-hydroxy)-propyl) - 1,2,3,4 - tetrahydroisoquinolines
BR181255/66A BR6681255D0 (pt) 1965-07-19 1966-07-13 Novos derivados tetrahidro-iso quinolinicos e um processo para sua fabricacao
BE684185D BE684185A (enrdf_load_stackoverflow) 1965-07-19 1966-07-15
ES0329218A ES329218A1 (es) 1965-07-19 1966-07-16 Un procedimiento para la preparacion de derivados de tetrahidro-isoquinolina.
NL6610093A NL6610093A (enrdf_load_stackoverflow) 1965-07-19 1966-07-18
DK373466AA DK117704B (da) 1965-07-19 1966-07-19 Analogifremgangsmåde til fremstilling af tetrahydroisoquinolinderivater.
FR69810A FR5796M (enrdf_load_stackoverflow) 1965-07-19 1966-07-19

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB30549/65A GB1079520A (en) 1965-07-19 1965-07-19 Novel tetrahydro-isoquinoline derivatives and a process for the manufacture thereof

Publications (1)

Publication Number Publication Date
GB1079520A true GB1079520A (en) 1967-08-16

Family

ID=10309382

Family Applications (1)

Application Number Title Priority Date Filing Date
GB30549/65A Expired GB1079520A (en) 1965-07-19 1965-07-19 Novel tetrahydro-isoquinoline derivatives and a process for the manufacture thereof

Country Status (11)

Country Link
US (1) US3450704A (enrdf_load_stackoverflow)
BE (1) BE684185A (enrdf_load_stackoverflow)
BR (1) BR6681255D0 (enrdf_load_stackoverflow)
CH (1) CH464922A (enrdf_load_stackoverflow)
DE (1) DE1695147A1 (enrdf_load_stackoverflow)
DK (1) DK117704B (enrdf_load_stackoverflow)
ES (1) ES329218A1 (enrdf_load_stackoverflow)
FR (1) FR5796M (enrdf_load_stackoverflow)
GB (1) GB1079520A (enrdf_load_stackoverflow)
IL (1) IL26040A (enrdf_load_stackoverflow)
NL (1) NL6610093A (enrdf_load_stackoverflow)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903091A (en) * 1970-02-06 1975-09-02 Sumitomo Chemical Co 1,2,3,4-Tetrahydroisoquinoline derivatives
US8604031B2 (en) * 2006-05-18 2013-12-10 Mannkind Corporation Intracellular kinase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT190517B (de) * 1954-06-22 1957-07-10 Wander Ag Dr A Verfahren zur Herstellung neuer, substituierter Tetrahydroisochinolinverbindungen
GB1032054A (en) * 1963-07-19 1966-06-08 Roche Products Ltd Substituted isoquinoline and piperazine derivatives and a process for the manufacture thereof

Also Published As

Publication number Publication date
DK117704B (da) 1970-05-25
FR5796M (enrdf_load_stackoverflow) 1968-02-12
ES329218A1 (es) 1967-08-16
DE1695147A1 (de) 1970-12-17
IL26040A (en) 1970-04-20
NL6610093A (enrdf_load_stackoverflow) 1967-01-20
BE684185A (enrdf_load_stackoverflow) 1967-01-16
CH464922A (de) 1968-11-15
BR6681255D0 (pt) 1973-12-26
US3450704A (en) 1969-06-17

Similar Documents

Publication Publication Date Title
Bentley et al. Novel analgesics and molecular rearrangements in the morphine-thebaine group. III. Alcohols of the 6, 14-endo-ethenotetrahydrooripavine series and derived analogs of N-allylnormorphine and-norcodeine
ES8705837A1 (es) Un procedimiento para la preparacion de derivados de naftaleno.
ES8603408A1 (es) Un procedimiento para la preparacion de un compuesto de 2-oxindol-1-carboxamida
GB1092394A (en) Benzomorphan derivatives and processes for their production
ES370394A1 (es) Procedimiento para la preparacion de nuevas 5-11-dihidro-6h-pirido (2,3-b) (1,4) benzodiazepin-6-ona y sus sales.
ES382551A1 (es) Un procedimiento para la preparacion de nuevas 2-amino-al- cohil-amino-tieno (3,2-d)pirimidinas.
GB1361840A (en) Substituted pyridines and polymers derived therefrom
GB1148717A (en) Phenylbenz (f)-2,5-oxazocine derivatives and homologues and pharmaceutical compositions
US3262938A (en) Carbocyclic substituted piperidyl dioxolanes
GB1079520A (en) Novel tetrahydro-isoquinoline derivatives and a process for the manufacture thereof
GB1104145A (en) Pyrazolo-pyridine derivatives
Burger The benzylisoquinoline alkaloids
ES341685A1 (es) Un procedimiento para la obtencion de nuevas piridil-tetra-hidroisoquinoleinas.
ES383006A1 (es) Un procedimiento para la preparacion de compuestos utiles como agentes neurolepticos.
US3352869A (en) Substituted and unsubstituted 4-(5h-dibenzo[a, d] cyclohepten-5-ylidene)-1-(amino ornitroso) piperidines
GB1106742A (en) New piperidine derivatives and the homologues thereof and process for their production
Kametani et al. A modified synthesis of codamine under eschweiler‐clarke conditions
KR890003768A (ko) 2-[(4- 피페리딜)메틸]- 벤조푸로[2,3-c]피리딘유도체, 그의 제법 및 치료에의 이용
GB1315575A (en) Schiffs bases from 2-aminoimidazole derivatives and the preparation thereof
GB1280424A (en) Novel xanthine compounds and means for obtaining the same
US3056791A (en) Isoquinoline derivatives
GB1140990A (en) Novel 1,2,3,4-tetrahydro-naphthalen-2-ones and a process for the preparation thereof
Jain 423. The synthesis of laudanosoline 4′, 6-dimethyl ether
US3578668A (en) 1-aminoalkylamino-benzo(b) quinolizines
GB1122212A (en) Process for the preparation of substituted piperidine derivatives