GB1074235A - Antibiotics r-451b(x)and r-451d(x)and processes for their manufacture - Google Patents
Antibiotics r-451b(x)and r-451d(x)and processes for their manufactureInfo
- Publication number
- GB1074235A GB1074235A GB28829/64A GB2882964A GB1074235A GB 1074235 A GB1074235 A GB 1074235A GB 28829/64 A GB28829/64 A GB 28829/64A GB 2882964 A GB2882964 A GB 2882964A GB 1074235 A GB1074235 A GB 1074235A
- Authority
- GB
- United Kingdom
- Prior art keywords
- antibiotics
- methanol
- spectrum
- pict
- infra
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003242 anti bacterial agent Substances 0.000 title abstract 5
- 229940088710 antibiotic agent Drugs 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 9
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 4
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 2
- 230000003115 biocidal effect Effects 0.000 abstract 2
- 230000003287 optical effect Effects 0.000 abstract 2
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- YXHKONLOYHBTNS-UHFFFAOYSA-N Diazomethane Chemical compound C=[N+]=[N-] YXHKONLOYHBTNS-UHFFFAOYSA-N 0.000 abstract 1
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 241000218955 Micromonospora carbonacea Species 0.000 abstract 1
- 241000204031 Mycoplasma Species 0.000 abstract 1
- 206010035664 Pneumonia Diseases 0.000 abstract 1
- 238000000862 absorption spectrum Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
- 208000004396 mastitis Diseases 0.000 abstract 1
- 244000000010 microbial pathogen Species 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 201000006509 pleuropneumonia Diseases 0.000 abstract 1
- 244000144977 poultry Species 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
- C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
- C12P19/485—Having two saccharide radicals bound through only oxygen to non-adjacent ring carbons of the cyclohexyl radical, e.g. gentamycin, kanamycin, sisomycin, verdamycin, mutamycin, tobramycin, nebramycin, antibiotics 66-40B, 66-40D, XK-62-2, 66-40, G-418, G-52
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/29—Micromonospora
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15226261A | 1961-11-14 | 1961-11-14 | |
| US18448462A | 1962-04-02 | 1962-04-02 | |
| US19841462A | 1962-05-23 | 1962-05-23 | |
| US21115462A | 1962-07-16 | 1962-07-16 | |
| US211153A US3091572A (en) | 1962-07-16 | 1962-07-16 | Gentamycin and method of production |
| US21180662A | 1962-07-23 | 1962-07-23 | |
| US29799963A | 1963-07-24 | 1963-07-24 | |
| US35416864A | 1964-03-23 | 1964-03-23 | |
| US76250468A | 1968-09-25 | 1968-09-25 | |
| US76912268A | 1968-10-21 | 1968-10-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1074235A true GB1074235A (en) | 1967-07-05 |
Family
ID=27581070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB28829/64A Expired GB1074235A (en) | 1961-11-14 | 1964-07-13 | Antibiotics r-451b(x)and r-451d(x)and processes for their manufacture |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE650943A (enrdf_load_stackoverflow) |
| FR (1) | FR117F (enrdf_load_stackoverflow) |
| GB (1) | GB1074235A (enrdf_load_stackoverflow) |
| LU (1) | LU42688A1 (enrdf_load_stackoverflow) |
| NL (3) | NL6408506A (enrdf_load_stackoverflow) |
| OA (1) | OA00868A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1178311A4 (en) * | 1999-05-10 | 2003-04-09 | Tomoya Sato | METHOD AND DEVICE FOR DETERMINING THE TYPE AND / OR STATE OF A SICKNESS, AND METHOD AND DEVICE FOR SCREENING MEDICINAL PRODUCTS. |
-
0
- FR FR117D patent/FR117F/fr active Active
- NL NL285188D patent/NL285188A/xx unknown
-
1962
- 1962-11-13 LU LU42688D patent/LU42688A1/xx unknown
-
1964
- 1964-07-13 GB GB28829/64A patent/GB1074235A/en not_active Expired
- 1964-07-24 NL NL6408506A patent/NL6408506A/xx unknown
- 1964-07-24 BE BE650943D patent/BE650943A/xx unknown
- 1964-12-22 OA OA50956A patent/OA00868A/xx unknown
-
1972
- 1972-02-10 NL NL7201760A patent/NL7201760A/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1178311A4 (en) * | 1999-05-10 | 2003-04-09 | Tomoya Sato | METHOD AND DEVICE FOR DETERMINING THE TYPE AND / OR STATE OF A SICKNESS, AND METHOD AND DEVICE FOR SCREENING MEDICINAL PRODUCTS. |
| US6743637B2 (en) | 1999-05-10 | 2004-06-01 | Tomoya Sato | Disease type and/or condition determination method and apparatus and drug screening method and apparatus |
Also Published As
| Publication number | Publication date |
|---|---|
| NL6408506A (enrdf_load_stackoverflow) | 1965-01-25 |
| LU42688A1 (enrdf_load_stackoverflow) | 1963-01-13 |
| BE650943A (enrdf_load_stackoverflow) | 1964-11-16 |
| NL285188A (enrdf_load_stackoverflow) | |
| FR117F (enrdf_load_stackoverflow) | |
| NL7201760A (enrdf_load_stackoverflow) | 1972-05-25 |
| OA00868A (fr) | 1968-03-22 |
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