GB1070745A - Apparatus for the determination of haemoglobin in blood - Google Patents

Apparatus for the determination of haemoglobin in blood

Info

Publication number
GB1070745A
GB1070745A GB21808/64A GB2180864A GB1070745A GB 1070745 A GB1070745 A GB 1070745A GB 21808/64 A GB21808/64 A GB 21808/64A GB 2180864 A GB2180864 A GB 2180864A GB 1070745 A GB1070745 A GB 1070745A
Authority
GB
United Kingdom
Prior art keywords
haemoglobin
blood
bridge
acid
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21808/64A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB1070745A publication Critical patent/GB1070745A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795—Porphyrin- or corrin-ring-containing peptides
    • G01N2333/805—Haemoglobins; Myoglobins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

1,070,745. Determining the haemoglobin content of blood electrically. H. G. NÍLLER. May 26, 1964 [May 29, 1963], No. 21808/64. Heading G1N. In an apparatus for determining the haemoglobin content of blood, a blood specimen is mixed with a known excess amount of a strong acid (e.g. N/100 hydrochloric acid) and the loss of conductivity due to the reaction of a portion of the acid with the haemoglobin is correlated with the amount of haemoglobin originally present. The apparatus includes a square wave generator 11 (as shown) feeding a bridge circuit via a centre tapped transformer 12. One arm of the bridge is provided by the resistance of the test mixture 2 between a pair of electrodes 4, 5 of a dip cell 3, when it is inserted in the mixture container 1. Another arm of the bridge is formed by a resistor assembly 13 which includes a negative temperature coefficient (N.T.C.) resistor to provide temperature compensation and arranged in thermal contact with the container 1. The unbalance output of the bridge is amplified by amplifier 14 which is coupled to a meter 16 calibrated in grams haemoglobin/100 millilitres of blood. Any electrolyte which will form a practically non-conductive reaction product with haemoglobin may be used such as soluble cyanides e.g. sodium and potassium cyanide, or acids such as hydrogen iodide, hydrogen azide or hydrogen sulphide, as an alternative to hydrochloric acid.
GB21808/64A 1963-05-29 1964-05-26 Apparatus for the determination of haemoglobin in blood Expired GB1070745A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEN0023243 1963-05-29

Publications (1)

Publication Number Publication Date
GB1070745A true GB1070745A (en) 1967-06-01

Family

ID=7342508

Family Applications (1)

Application Number Title Priority Date Filing Date
GB21808/64A Expired GB1070745A (en) 1963-05-29 1964-05-26 Apparatus for the determination of haemoglobin in blood

Country Status (3)

Country Link
US (1) US3374063A (en)
FR (1) FR1396897A (en)
GB (1) GB1070745A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492095A (en) * 1967-10-05 1970-01-27 Harold B Tillen Product for and method of testing blood for the presence of hemoglobin s
GB8619627D0 (en) * 1986-08-12 1986-09-24 Genetics Int Inc Electrochemical assay

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2555937A (en) * 1949-08-25 1951-06-05 Robert L Rosenthal Method and apparatus for measuring resistance of blood during clotting
US3297943A (en) * 1962-08-22 1967-01-10 Exxon Research Engineering Co Electrometric system with automatic temperature compensating means

Also Published As

Publication number Publication date
US3374063A (en) 1968-03-19
FR1396897A (en) 1965-04-23

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