GB1068497A - New tertiary amine and process for its manufacture - Google Patents
New tertiary amine and process for its manufactureInfo
- Publication number
- GB1068497A GB1068497A GB547166A GB547166A GB1068497A GB 1068497 A GB1068497 A GB 1068497A GB 547166 A GB547166 A GB 547166A GB 547166 A GB547166 A GB 547166A GB 1068497 A GB1068497 A GB 1068497A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- dimethylaminomethyl
- diphenyl
- acid addition
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000003512 tertiary amines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- BTEPCCLXMPVCIW-UHFFFAOYSA-N 3-[(dimethylamino)methyl]-1,2-diphenylbut-3-en-2-ol Chemical compound C1(=CC=CC=C1)CC(C(=C)CN(C)C)(O)C1=CC=CC=C1 BTEPCCLXMPVCIW-UHFFFAOYSA-N 0.000 abstract 2
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
- 239000012458 free base Substances 0.000 abstract 2
- 229910052749 magnesium Inorganic materials 0.000 abstract 2
- 239000011777 magnesium Substances 0.000 abstract 2
- OTKCEEWUXHVZQI-UHFFFAOYSA-N 1,2-diphenylethanone Chemical compound C=1C=CC=CC=1C(=O)CC1=CC=CC=C1 OTKCEEWUXHVZQI-UHFFFAOYSA-N 0.000 abstract 1
- YMFWYDYJHRGGPF-UHFFFAOYSA-N 2,3-dibromoprop-1-ene Chemical compound BrCC(Br)=C YMFWYDYJHRGGPF-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- QNYRJYLGBCLNFA-UHFFFAOYSA-N [3-[(dimethylamino)methyl]-1,2-diphenylbut-3-en-2-yl] propanoate Chemical compound C=1C=CC=CC=1C(OC(=O)CC)(C(=C)CN(C)C)CC1=CC=CC=C1 QNYRJYLGBCLNFA-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Remote Monitoring And Control Of Power-Distribution Networks (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH267765A CH465584A (de) | 1965-02-26 | 1965-02-26 | Verfahren zur Herstellung von neuen tertiären Aminen |
| CH902865 | 1965-06-28 | ||
| CH1311165 | 1965-09-22 | ||
| CH1811965 | 1965-12-30 | ||
| CH1811865 | 1965-12-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1068497A true GB1068497A (en) | 1967-05-10 |
Family
ID=27509073
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB547366A Expired GB1117623A (en) | 1965-02-26 | 1966-02-08 | New tertiary amines and process for their manufacture |
| GB547166A Expired GB1068497A (en) | 1965-02-26 | 1966-02-08 | New tertiary amine and process for its manufacture |
| GB547266A Expired GB1117622A (en) | 1965-02-26 | 1966-02-08 | New tertiary amines and process for their manufacture |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB547366A Expired GB1117623A (en) | 1965-02-26 | 1966-02-08 | New tertiary amines and process for their manufacture |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB547266A Expired GB1117622A (en) | 1965-02-26 | 1966-02-08 | New tertiary amines and process for their manufacture |
Country Status (16)
| Country | Link |
|---|---|
| BE (3) | BE677036A (https=) |
| BR (3) | BR6677344D0 (https=) |
| CH (2) | CH475190A (https=) |
| CY (1) | CY556A (https=) |
| DE (2) | DE1568254A1 (https=) |
| DK (3) | DK123023B (https=) |
| FI (1) | FI44601C (https=) |
| FR (4) | FR1468478A (https=) |
| GB (3) | GB1117623A (https=) |
| IL (1) | IL25127A (https=) |
| LU (1) | LU50473A1 (https=) |
| MY (1) | MY7000162A (https=) |
| NL (3) | NL6602535A (https=) |
| NO (1) | NO115389B (https=) |
| SE (3) | SE348454B (https=) |
| SU (1) | SU372806A3 (https=) |
-
1965
- 1965-02-26 CH CH1401167A patent/CH475190A/de not_active IP Right Cessation
- 1965-02-26 CH CH267765A patent/CH465584A/de unknown
-
1966
- 1966-02-07 IL IL2512766A patent/IL25127A/xx unknown
- 1966-02-08 GB GB547366A patent/GB1117623A/en not_active Expired
- 1966-02-08 GB GB547166A patent/GB1068497A/en not_active Expired
- 1966-02-08 GB GB547266A patent/GB1117622A/en not_active Expired
- 1966-02-16 LU LU50473A patent/LU50473A1/xx unknown
- 1966-02-17 DE DE19661568254 patent/DE1568254A1/de active Pending
- 1966-02-17 FR FR50038A patent/FR1468478A/fr not_active Expired
- 1966-02-17 FR FR50039A patent/FR1468479A/fr not_active Expired
- 1966-02-17 DE DE19661793640 patent/DE1793640B1/de active Pending
- 1966-02-23 FI FI44866A patent/FI44601C/fi active
- 1966-02-24 BR BR17734466A patent/BR6677344D0/pt unknown
- 1966-02-24 BR BR17733766A patent/BR6677337D0/pt unknown
- 1966-02-24 BR BR17733666A patent/BR6677336D0/pt unknown
- 1966-02-25 SE SE246766A patent/SE348454B/xx unknown
- 1966-02-25 NL NL6602535A patent/NL6602535A/xx unknown
- 1966-02-25 NO NO16185366A patent/NO115389B/no unknown
- 1966-02-25 DK DK98666A patent/DK123023B/da unknown
- 1966-02-25 BE BE677036D patent/BE677036A/xx unknown
- 1966-02-25 BE BE677035D patent/BE677035A/xx unknown
- 1966-02-25 BE BE677034D patent/BE677034A/xx unknown
- 1966-02-25 DK DK98566A patent/DK118601B/da unknown
- 1966-02-25 NL NL6602537A patent/NL6602537A/xx unknown
- 1966-02-25 NL NL6602536A patent/NL6602536A/xx unknown
- 1966-02-25 DK DK98766A patent/DK122878B/da unknown
- 1966-02-25 SE SE246666A patent/SE348724B/xx unknown
- 1966-02-25 SE SE246566A patent/SE325266B/xx unknown
- 1966-03-29 SU SU1064790A patent/SU372806A3/ru active
- 1966-05-10 FR FR60915A patent/FR5349M/fr not_active Expired
- 1966-05-10 FR FR60914A patent/FR5348M/fr not_active Expired
-
1970
- 1970-08-19 CY CY55670A patent/CY556A/xx unknown
- 1970-12-31 MY MY7000162A patent/MY7000162A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES369624A1 (es) | Procedimiento para la produccion de derivados de alcanola- mina. | |
| GB1307455A (en) | 2,-hydroxy-3-phenylpropiophenone derivatives | |
| GB1068497A (en) | New tertiary amine and process for its manufacture | |
| ES375067A1 (es) | Un metodo para la preparacion de acidos 5 beta-tauroceleni-cos y acidos 5 beta-taurocoladienicos. | |
| IL46725A0 (en) | Derivative of gentamine and its salts,process of preparation and pharmaceutical compositions | |
| ES405973A1 (es) | Un procedimiento para la preparacion de esteres de cicloal-quenona. | |
| ES417396A1 (es) | Un procedimiento para la produccion de una composicion far-maceutica. | |
| ES444526A1 (es) | Procedimiento para preparar un derivado aromatico de guani- dina. | |
| ES384802A1 (es) | Un procedimiento para la preparacion de benzopiran-5-oles. | |
| GB1058468A (en) | Improvements in or relating to (2-amino-1-hydroxyethyl)-thianaphthenes | |
| ES397454A1 (es) | Un procedimiento para la preparacion de derivados de tetra-hidro-isoquinolina. | |
| ES317053A3 (es) | Un procedimiento para preparar nuevas composiciones farmaceuticas que comprenden compuestos de 1, 2-difenil-2-aciloxi3-metil-n-butilamina | |
| GB1266430A (https=) | ||
| ES314547A1 (es) | Procedimiento para la preparacion de una nueva composicion farmaceutica inyectable a base del compuesto complejo de antimonio (iii)-acido 2,3-dimercaptosuccinico. | |
| ES360153A1 (es) | Procedimiento para la preparacion de bencilideno-amido-hi- dracinas. | |
| GB903355A (en) | Furfurylmercaptopyridine compounds and preparation thereof | |
| GB1317429A (en) | Analgesic preparations | |
| GB1123974A (en) | Benzofuran derivatives and process for preparing the same | |
| ES435087A1 (es) | Un procedimiento de preparacion del 3-oxo-17 beta-n-amiloxiestra-4, 9, 11-trieno. | |
| GB1102043A (en) | Phenothiazine salts | |
| GB1109964A (en) | Complex of theophylline and soluble saccharin, process for its preparation and therapeutic composition comprising same | |
| ES411984A1 (es) | Procedimiento para la preparacion de compuestos isoprenoi- des aciclicos que contienen nitrogeno. | |
| GB1253818A (en) | Novel amines with pharmaceutical applications | |
| ES338945A1 (es) | Un procedimiento para la preparacion de agentes analgesicosy antitusivos. | |
| GB1011048A (en) | Pyrazolopyrimidine derivative and the production thereof |