GB1253818A - Novel amines with pharmaceutical applications - Google Patents

Novel amines with pharmaceutical applications

Info

Publication number
GB1253818A
GB1253818A GB5924668A GB5924668A GB1253818A GB 1253818 A GB1253818 A GB 1253818A GB 5924668 A GB5924668 A GB 5924668A GB 5924668 A GB5924668 A GB 5924668A GB 1253818 A GB1253818 A GB 1253818A
Authority
GB
United Kingdom
Prior art keywords
isobutyl
dec
reacting
pharmaceutical applications
isoamyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5924668A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CT EUROP DE RECH S MAUVERNAY
Centre Europeen de Recherches Mauvernay CERM
Original Assignee
CT EUROP DE RECH S MAUVERNAY
Centre Europeen de Recherches Mauvernay CERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CT EUROP DE RECH S MAUVERNAY, Centre Europeen de Recherches Mauvernay CERM filed Critical CT EUROP DE RECH S MAUVERNAY
Publication of GB1253818A publication Critical patent/GB1253818A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1,253,818. Basic ethers. CENTRE EUROPEEN DE RECHERCHES MAUVERNAY. 12 Dec., 1968 [15 Dec., 1967], No. 59246/68. Heading C2C. Compounds of the formula (R=isobutyl, isoamyl) and their acid addition and quaternary ammonium salts are prepared by reacting styrene with isobutyl or isoamyl alcohol and tert.-butyl hypobromite and reacting the resulting PhCH(OR)CH 2 Br with pyrrolidine, optionally followed by salt formation. The above compounds possess spasmolytic, vagolytic, anti-cholinergic, anti-parkinson and antidepressant activity, and may be administered in the form of pharmaceutical preparations containing them together with a carrier. Reference has been directed by the Comptroller to Specification 1,141,606.
GB5924668A 1967-12-15 1968-12-12 Novel amines with pharmaceutical applications Expired GB1253818A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR132360A FR357F (en) 1967-12-15 1967-12-15

Publications (1)

Publication Number Publication Date
GB1253818A true GB1253818A (en) 1971-11-17

Family

ID=8643257

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5924668A Expired GB1253818A (en) 1967-12-15 1968-12-12 Novel amines with pharmaceutical applications

Country Status (7)

Country Link
BE (1) BE724119A (en)
CH (1) CH491909A (en)
DE (1) DE1811767A1 (en)
ES (1) ES361103A1 (en)
FR (1) FR357F (en)
GB (1) GB1253818A (en)
SE (1) SE357967B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0581456A1 (en) * 1992-07-07 1994-02-02 R.J. Reynolds Tobacco Company Use of phenylpyrrolidines for the manufacture of a medicament for the treatment of neurodegenerative diseases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0581456A1 (en) * 1992-07-07 1994-02-02 R.J. Reynolds Tobacco Company Use of phenylpyrrolidines for the manufacture of a medicament for the treatment of neurodegenerative diseases

Also Published As

Publication number Publication date
ES361103A1 (en) 1971-02-16
FR357F (en) 1973-07-27
DE1811767A1 (en) 1969-10-16
BE724119A (en) 1969-05-02
CH491909A (en) 1970-06-15
SE357967B (en) 1973-07-16

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