GB1063366A - Improvements relating to derivatives of adamantane - Google Patents
Improvements relating to derivatives of adamantaneInfo
- Publication number
- GB1063366A GB1063366A GB21842/66A GB2184266A GB1063366A GB 1063366 A GB1063366 A GB 1063366A GB 21842/66 A GB21842/66 A GB 21842/66A GB 2184266 A GB2184266 A GB 2184266A GB 1063366 A GB1063366 A GB 1063366A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- formula
- acid
- alkoxy
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ORILYTVJVMAKLC-UHFFFAOYSA-N adamantane Chemical class C1C(C2)CC3CC1CC2C3 ORILYTVJVMAKLC-UHFFFAOYSA-N 0.000 title 1
- -1 hydroxy- Chemical class 0.000 abstract 15
- 150000003839 salts Chemical class 0.000 abstract 5
- JACSSWDJQLXNOO-UHFFFAOYSA-N 4-[(2-chlorophenyl)methyl]-5-oxo-4-phenylhexanoic acid Chemical compound C=1C=CC=CC=1C(CCC(O)=O)(C(=O)C)CC1=CC=CC=C1Cl JACSSWDJQLXNOO-UHFFFAOYSA-N 0.000 abstract 4
- 125000003277 amino group Chemical group 0.000 abstract 4
- 125000004122 cyclic group Chemical group 0.000 abstract 4
- 125000004178 (C1-C4) alkyl group Chemical class 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 3
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 abstract 3
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 2
- 125000006274 (C1-C3)alkoxy group Chemical group 0.000 abstract 2
- HGCUKZACTCRRHD-UHFFFAOYSA-N 1-(1-adamantyl)-3-(4-methylphenyl)sulfonylurea Chemical class C1=CC(C)=CC=C1S(=O)(=O)NC(=O)NC1(C2)CC(C3)CC2CC3C1 HGCUKZACTCRRHD-UHFFFAOYSA-N 0.000 abstract 2
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 230000000840 anti-viral effect Effects 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- WLJNZVDCPSBLRP-UHFFFAOYSA-N pamoic acid Chemical compound C1=CC=C2C(CC=3C4=CC=CC=C4C=C(C=3O)C(=O)O)=C(O)C(C(O)=O)=CC2=C1 WLJNZVDCPSBLRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004344 phenylpropyl group Chemical group 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- DKNWSYNQZKUICI-UHFFFAOYSA-N amantadine Chemical class C1C(C2)CC3CC2CC1(N)C3 DKNWSYNQZKUICI-UHFFFAOYSA-N 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 239000003925 fat Substances 0.000 abstract 1
- 235000019197 fats Nutrition 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 235000010755 mineral Nutrition 0.000 abstract 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229960004889 salicylic acid Drugs 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13415761A | 1961-08-28 | 1961-08-28 | |
| US31807363A | 1963-10-22 | 1963-10-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1063366A true GB1063366A (en) | 1967-03-30 |
Family
ID=26832027
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB21842/66A Expired GB1063366A (en) | 1961-08-28 | 1964-03-19 | Improvements relating to derivatives of adamantane |
| GB11633/64A Expired GB1063365A (en) | 1961-08-28 | 1964-03-19 | Improvements relating to derivatives of adamantane |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB11633/64A Expired GB1063365A (en) | 1961-08-28 | 1964-03-19 | Improvements relating to derivatives of adamantane |
Country Status (10)
| Country | Link |
|---|---|
| BR (1) | BR6457700D0 (cg-RX-API-DMAC7.html) |
| DE (2) | DE1793384A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK127595B (cg-RX-API-DMAC7.html) |
| FI (1) | FI42207B (cg-RX-API-DMAC7.html) |
| FR (1) | FR1559564A (cg-RX-API-DMAC7.html) |
| GB (2) | GB1063366A (cg-RX-API-DMAC7.html) |
| LU (1) | LU45675A1 (cg-RX-API-DMAC7.html) |
| NL (1) | NL6403294A (cg-RX-API-DMAC7.html) |
| NO (1) | NO121269B (cg-RX-API-DMAC7.html) |
| SE (1) | SE321923B (cg-RX-API-DMAC7.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010112946A1 (en) | 2009-03-31 | 2010-10-07 | Rudjer Boskovic Institute | Adamantane bisurea derivatives, method of preparation and application in anion sensing |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5576355A (en) * | 1993-06-04 | 1996-11-19 | Mobil Oil Corp. | Diamondoid derivatives for pharmaceutical use |
-
1964
- 1964-03-14 NO NO152434A patent/NO121269B/no unknown
- 1964-03-17 LU LU45675D patent/LU45675A1/xx unknown
- 1964-03-18 BR BR157700/64A patent/BR6457700D0/pt unknown
- 1964-03-19 GB GB21842/66A patent/GB1063366A/en not_active Expired
- 1964-03-19 GB GB11633/64A patent/GB1063365A/en not_active Expired
- 1964-03-20 SE SE3521/64A patent/SE321923B/xx unknown
- 1964-03-24 DK DK149864AA patent/DK127595B/da unknown
- 1964-03-25 FI FI0647/64A patent/FI42207B/fi active
- 1964-03-26 NL NL6403294A patent/NL6403294A/xx unknown
- 1964-03-28 DE DE19641793384 patent/DE1793384A1/de active Pending
- 1964-03-28 DE DE19641468756 patent/DE1468756B2/de active Granted
- 1964-04-13 FR FR1559564D patent/FR1559564A/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010112946A1 (en) | 2009-03-31 | 2010-10-07 | Rudjer Boskovic Institute | Adamantane bisurea derivatives, method of preparation and application in anion sensing |
Also Published As
| Publication number | Publication date |
|---|---|
| DK127595B (da) | 1973-12-03 |
| SE321923B (cg-RX-API-DMAC7.html) | 1970-03-23 |
| LU45675A1 (cg-RX-API-DMAC7.html) | 1964-06-15 |
| DE1468756C3 (cg-RX-API-DMAC7.html) | 1974-02-14 |
| FI42207B (cg-RX-API-DMAC7.html) | 1970-03-02 |
| DE1468756B2 (de) | 1973-07-05 |
| DE1468756A1 (de) | 1969-08-07 |
| GB1063365A (en) | 1967-03-30 |
| NL6403294A (cg-RX-API-DMAC7.html) | 1965-04-23 |
| DE1793384A1 (de) | 1972-02-03 |
| BR6457700D0 (pt) | 1973-07-17 |
| FR1559564A (cg-RX-API-DMAC7.html) | 1969-03-14 |
| NO121269B (cg-RX-API-DMAC7.html) | 1971-02-08 |
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