GB1057000A - Method of making tablets for testing the sensitivity of bacteria to an antibiotic - Google Patents

Method of making tablets for testing the sensitivity of bacteria to an antibiotic

Info

Publication number
GB1057000A
GB1057000A GB50237/64A GB5023764A GB1057000A GB 1057000 A GB1057000 A GB 1057000A GB 50237/64 A GB50237/64 A GB 50237/64A GB 5023764 A GB5023764 A GB 5023764A GB 1057000 A GB1057000 A GB 1057000A
Authority
GB
United Kingdom
Prior art keywords
antibiotic
tablet
sodium sulphate
tablets
sterilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB50237/64A
Inventor
Ionescu Stoian
Viorica Florea
Dan Arizan
Const Iliesou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DEPUTY MINISTER OF MINISTE
Original Assignee
DEPUTY MINISTER OF MINISTE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DEPUTY MINISTER OF MINISTE filed Critical DEPUTY MINISTER OF MINISTE
Priority to GB50237/64A priority Critical patent/GB1057000A/en
Publication of GB1057000A publication Critical patent/GB1057000A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A tablet for testing the sensitivity of bacteria to an antibiotic is made by preparing a powder of an inert synthetic plastics material insoluble in water and a powder of the antibiotic, mixing the powders to form a homogeneous mixture and pressing the mixture to make a tablet. The homogeneous mixture may include sodium sulphate to increase the soluble matter in the tablets and thereby their porosity. According to an example powder particles, all of a size passing through a 400 mesh sieve, of autoclave - sterilized and dried polyethylene, sterilized and dried sodium sulphate and Penicillin G were mixed with homogeneous in quantities sufficient to obtain batches of tablets each 5 mm. in diameter and weighing 0.017 g. Each tablet contained 0.002 g. of anhydrous sodium sulphate and 10 I.U. of the antibiotic. A letter or coded symbol was impressed on each tablet.ALSO:A tablet for testing the sensitivity of bacteria to an antibiotic is prepared by mixing powder particles, all of a size passing through a 400-mesh sieve, of autoclave-sterilized and dried polyethylene, sterilized and dried sodium sulphate and Penicillin G, and pressing the mixture into tablets 5 mm. in diameter and weighing 0.017 g. Each tablet contains 0.002 g. of anhydrous sodium sulphate and 10 I.U. of the antibiotic. The sodium sulphate increases the soluble matter in the tablets and thereby their porosity.
GB50237/64A 1964-12-10 1964-12-10 Method of making tablets for testing the sensitivity of bacteria to an antibiotic Expired GB1057000A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB50237/64A GB1057000A (en) 1964-12-10 1964-12-10 Method of making tablets for testing the sensitivity of bacteria to an antibiotic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB50237/64A GB1057000A (en) 1964-12-10 1964-12-10 Method of making tablets for testing the sensitivity of bacteria to an antibiotic

Publications (1)

Publication Number Publication Date
GB1057000A true GB1057000A (en) 1967-02-01

Family

ID=10455180

Family Applications (1)

Application Number Title Priority Date Filing Date
GB50237/64A Expired GB1057000A (en) 1964-12-10 1964-12-10 Method of making tablets for testing the sensitivity of bacteria to an antibiotic

Country Status (1)

Country Link
GB (1) GB1057000A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2810056A1 (en) * 1977-03-16 1978-09-28 Beecham Group Ltd TABLETS CONTAINING TEST REAGENTS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2810056A1 (en) * 1977-03-16 1978-09-28 Beecham Group Ltd TABLETS CONTAINING TEST REAGENTS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE

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