GB1053301A - - Google Patents
Info
- Publication number
- GB1053301A GB1053301A GB1053301DA GB1053301A GB 1053301 A GB1053301 A GB 1053301A GB 1053301D A GB1053301D A GB 1053301DA GB 1053301 A GB1053301 A GB 1053301A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid addition
- formula
- addition salt
- phenyl
- jan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002253 acid Substances 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 5
- RMVRSNDYEFQCLF-UHFFFAOYSA-N thiophenol Chemical compound SC1=CC=CC=C1 RMVRSNDYEFQCLF-UHFFFAOYSA-N 0.000 abstract 3
- -1 trifluoromethylphenyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000012458 free base Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- SZIFAVKTNFCBPC-UHFFFAOYSA-N 2-chloroethanol Chemical compound OCCCl SZIFAVKTNFCBPC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000002908 adrenolytic effect Effects 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 239000012670 alkaline solution Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000004885 piperazines Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25104763A | 1963-01-14 | 1963-01-14 | |
| US25778363A | 1963-02-11 | 1963-02-11 | |
| US25778463A | 1963-02-11 | 1963-02-11 | |
| US27189063A | 1963-04-10 | 1963-04-10 | |
| US32134263A | 1963-11-04 | 1963-11-04 | |
| US32133463A | 1963-11-04 | 1963-11-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1053301A true GB1053301A (enrdf_load_stackoverflow) |
Family
ID=27559375
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1053301D Active GB1053301A (enrdf_load_stackoverflow) | 1963-01-14 | ||
| GB170264A Expired GB1061571A (en) | 1963-01-14 | 1964-01-14 | N,n'-disubstituted piperazines and process for their manufacture |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB170264A Expired GB1061571A (en) | 1963-01-14 | 1964-01-14 | N,n'-disubstituted piperazines and process for their manufacture |
Country Status (5)
| Country | Link |
|---|---|
| BE (3) | BE642429A (enrdf_load_stackoverflow) |
| CH (5) | CH449635A (enrdf_load_stackoverflow) |
| DE (1) | DE1232587B (enrdf_load_stackoverflow) |
| FR (1) | FR3734M (enrdf_load_stackoverflow) |
| GB (2) | GB1061571A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0290958A3 (de) * | 1987-05-12 | 1990-08-08 | Hoechst Aktiengesellschaft | Diarylalkyl-substituierte Alkylamine, Verfahren zu ihrer Herstellung, ihre Verwendung sowie sie enthaltende Arzneimittel |
| AU762726B2 (en) * | 1998-03-31 | 2003-07-03 | Acadia Pharmaceuticals, Inc. | Compounds with activity on muscarinic receptors |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5513209A (en) * | 1978-07-11 | 1980-01-30 | Synthelabo | Antidepressive made of piperazine derivative |
| JPS56115769A (en) * | 1980-02-18 | 1981-09-11 | Tanabe Seiyaku Co Ltd | Piperazine derivative and its preparation |
| FR2568878B1 (fr) * | 1984-08-07 | 1986-11-21 | Cortial | Nouveaux derives de (phenylpiperazinylethylamine ethoxy)-4 phenol, leur methode de preparation et leur application therapeutique |
| US6528529B1 (en) | 1998-03-31 | 2003-03-04 | Acadia Pharmaceuticals Inc. | Compounds with activity on muscarinic receptors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1197461B (de) | 1962-02-23 | 1965-07-29 | Abbott Lab | Verfahren zur Herstellung von 1, 4-Diazin-derivaten |
-
0
- GB GB1053301D patent/GB1053301A/en active Active
-
1964
- 1964-01-09 CH CH449367A patent/CH449635A/de unknown
- 1964-01-09 CH CH449267A patent/CH449634A/de unknown
- 1964-01-09 CH CH22764A patent/CH449030A/de unknown
- 1964-01-09 CH CH449167A patent/CH449633A/de unknown
- 1964-01-09 CH CH449467A patent/CH449636A/de unknown
- 1964-01-10 DE DEC31848A patent/DE1232587B/de active Pending
- 1964-01-13 BE BE642429A patent/BE642429A/xx unknown
- 1964-01-13 BE BE642428A patent/BE642428A/xx unknown
- 1964-01-13 BE BE642427A patent/BE642427A/xx unknown
- 1964-01-14 GB GB170264A patent/GB1061571A/en not_active Expired
- 1964-04-07 FR FR969932A patent/FR3734M/fr not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0290958A3 (de) * | 1987-05-12 | 1990-08-08 | Hoechst Aktiengesellschaft | Diarylalkyl-substituierte Alkylamine, Verfahren zu ihrer Herstellung, ihre Verwendung sowie sie enthaltende Arzneimittel |
| AU762726B2 (en) * | 1998-03-31 | 2003-07-03 | Acadia Pharmaceuticals, Inc. | Compounds with activity on muscarinic receptors |
Also Published As
| Publication number | Publication date |
|---|---|
| GB1061571A (en) | 1967-03-15 |
| CH449634A (de) | 1968-01-15 |
| CH449633A (de) | 1968-01-15 |
| CH449636A (de) | 1968-01-15 |
| CH449030A (de) | 1967-12-31 |
| BE642429A (enrdf_load_stackoverflow) | 1964-07-13 |
| BE642427A (enrdf_load_stackoverflow) | 1964-07-13 |
| FR3734M (fr) | 1965-12-06 |
| CH449635A (de) | 1968-01-15 |
| BE642428A (enrdf_load_stackoverflow) | 1964-07-13 |
| DE1232587B (de) | 1967-01-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES480542A1 (es) | Metodo para producir derivados de imidazol. | |
| ES409907A1 (es) | Procedimiento para la preparacion de imidazolil-(2)-carbi- noles. | |
| ES433145A1 (es) | Procedimiento para preparar derivados de fenoxipropilamina. | |
| GB1442118A (en) | Piperidine derivatives | |
| GB1149139A (en) | New herbicidal compounds and compositions | |
| GB1475271A (en) | 1-aryl-2-1-imidazolyl-alkyl ethers and thioethers and their use as antifungal agents | |
| ES8101035A1 (es) | Un procedimiento de preparacion de nuevos derivados de 3-(a-minoetil)fenol | |
| GB1377231A (en) | Basically substituted benzyl-phthalazinone derivatives acid addition salts thereof and process for the production thereof | |
| GB1369248A (en) | Amides the preparation thereof and their use in pharmacjeutical compositions | |
| GB1053301A (enrdf_load_stackoverflow) | ||
| GB1173227A (en) | Amino-Isoquinolines | |
| IL43722A (en) | 2-aminomethyleneindanones and pharmaceutical compositions containing them | |
| ES8301971A1 (es) | Un proceso para la preparacion de derivados de n-alquilimi- dazoles sustituidos | |
| GB1171670A (en) | Derivatives of 4-Aryl-3-Hydroxybutyric Acid | |
| GB1322451A (en) | 3-amino-5-benzyl-1,2,4-oxadiazoles | |
| GB1457038A (en) | Amino derivatives of 1,4-benzodioxan | |
| GB1505899A (en) | 3,4-dihydrocarbostyril derivatives | |
| GB1043510A (en) | D-(--)-n-alkyl-1-phenyl-2-aminoethanols | |
| GB1462521A (en) | Triazole derivatives | |
| GB1315849A (en) | 1,2,3-trithiane derivatives | |
| GB1449802A (en) | Piperazine derivatives and compositions containing them for treating parkinsons disease | |
| GB1090283A (en) | (2-aminoethyl)-hydroquinones | |
| ES341324A1 (es) | Un procedimiento para la preparacion de pirazinoilguanidi- nas y pirazinamidoguanidinas. | |
| ES428673A1 (es) | Procedimiento para la obtencion de derivados de nitrobenzo-fenona sustituidos. | |
| GB1245155A (en) | NOVEL 5-SUBSTITUTED-gamma-CARBOLINE DERIVATIVES AND THE SALTS THEREOF |