GB1053035A - - Google Patents

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Publication number
GB1053035A
GB1053035A GB1053035DA GB1053035A GB 1053035 A GB1053035 A GB 1053035A GB 1053035D A GB1053035D A GB 1053035DA GB 1053035 A GB1053035 A GB 1053035A
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GB
United Kingdom
Prior art keywords
alkyl
reacting
atoms
amine
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of GB1053035A publication Critical patent/GB1053035A/en
Active legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/52—Nitrogen atoms not forming part of a nitro radical with hetero atoms directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/76—Dibenzothiophenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1,053,035. Guanyl hydrazones. FARBENFABRIKEN BAYER A.G. April 15, 1965 [April 15, 1964], No. 16407/65. Heading C2C. Guanyl hydrazone derivatives of polycyclic aromatic compounds which contain two or more benzene rings in which two benzene rings have two common C atoms or are joined together by two members selected from direct bonds, N, S, O or C atoms and CO groups, said polycyclic aromatic compounds containing at least two CO groups, which may be nuclear or each of which may form part of the same or different side chain containing up to 10 C atoms, said side chain optionally also containing an aryl group, the guanyl hydrazone substituent having the general formula wherein A is H or an alkyl residue of 1-6 C and B is H or an alkyl residue of 1-6 C, which may be joined to A, or an NO 2 , group or a residue of the formula where R and R 1 are C 1-6 alkyl radicals which may be joined to form a ring and n is 2, 3 or 4 ; and their salts with pharmaceutically acceptable, non-toxic acids are prepared by reacting an appropriate carbonyl compound with (a) an aminoguanidine or (b) with a thiosemicarbazide and reacting the thiosemicarbazone with an amine ANH 2 or first forming the S-alkyl isothio semicarbazone then reacting this with the amine or (c) with an alkyl isothiosemicarbazone H 2 N.NH-C(: NA) S-alkyl and reacting this with an amine BNH 2 or (d) with hydrazine and the product subsequently with a cyanamide B-NH-CN or with an S-alkylisothiourea Alkyl-S-C(: NA)NHB.
GB1053035D 1964-04-15 Active GB1053035A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1964F0042610 DE1239291B (en) 1964-04-15 1964-04-15 Process for the preparation of guanyl hydrazone of aromatic polycyclic carbonyl compounds

Publications (1)

Publication Number Publication Date
GB1053035A true GB1053035A (en)

Family

ID=7099171

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1053035D Active GB1053035A (en) 1964-04-15

Country Status (2)

Country Link
DE (1) DE1239291B (en)
GB (1) GB1053035A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2446285A1 (en) * 1978-09-05 1980-08-08 American Cyanamid Co Bis:hydrazone derivs. of anthracene 9,10-di:carbonyl cpds. - useful as antibacterials and antitumour agents
EP0018850A1 (en) * 1979-05-07 1980-11-12 American Cyanamid Company Substituted 9,10-anthracene-bis hydrazones and pharmaceutical compositions containing same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104755512B (en) * 2012-10-19 2016-05-18 日本瑞翁株式会社 Polymerizable compound, polymerizable composition, polymerizable composition, macromolecule and optically anisotropic body

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2446285A1 (en) * 1978-09-05 1980-08-08 American Cyanamid Co Bis:hydrazone derivs. of anthracene 9,10-di:carbonyl cpds. - useful as antibacterials and antitumour agents
EP0018850A1 (en) * 1979-05-07 1980-11-12 American Cyanamid Company Substituted 9,10-anthracene-bis hydrazones and pharmaceutical compositions containing same

Also Published As

Publication number Publication date
DE1239291B (en) 1967-04-27

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