GB1044338A - Novel alpha-keto gamma lactone derivatives and method for preparing same - Google Patents
Novel alpha-keto gamma lactone derivatives and method for preparing sameInfo
- Publication number
- GB1044338A GB1044338A GB1466863A GB1466863A GB1044338A GB 1044338 A GB1044338 A GB 1044338A GB 1466863 A GB1466863 A GB 1466863A GB 1466863 A GB1466863 A GB 1466863A GB 1044338 A GB1044338 A GB 1044338A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- phenyl
- carbon atoms
- formula
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises compounds of the formula <FORM:1044338/C2/1> in which the X and Y represent an alkyl, carbalkoxy or alkoxy group containing up to 8 carbon atoms, a cycloalkyl, cycloalkenyl, or cycloalkoxy group containing from 3 to 7 carbon atoms, a phenyl or monohalogenated phenyl group, an alkoxyphenyl or alkylphenyl group in which the alkoxy or alkyl moiety contains 1 to 8 carbon atoms, or a phenyl, monohalogenated phenyl, naphthyl, biphenylyl, phenylamino or benzyloxy group, provided that one of the symbols X and Y represents an alkoxy, benzyl-oxy or cycloalkoxy group; salts with inorganic or organic bases with the enol form of these compounds; and a process for their preparation comprising reacting an acyl pyruvic acid or ester of the formula X-CO-CH2-CO-COOZ (in which Z represents a hydrogen atom or an alkyl or aralkyl group) with an aldehyde of the formula Y-CO-CHO. Pharmaceutical compositions, having anti-phlogistic, antipyretic and anti-inflammatory properties, comprise a compound of the invention together with a diluent.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18688062A | 1962-04-12 | 1962-04-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1044338A true GB1044338A (en) | 1966-09-28 |
Family
ID=22686654
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1466863A Expired GB1044338A (en) | 1962-04-12 | 1963-04-11 | Novel alpha-keto gamma lactone derivatives and method for preparing same |
Country Status (2)
Country | Link |
---|---|
CH (1) | CH427770A (en) |
GB (1) | GB1044338A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5508302A (en) * | 1994-09-28 | 1996-04-16 | American Home Products Corporation | Phospholipase A2 inhibitors |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3229026A1 (en) * | 1982-08-04 | 1984-02-09 | Basf Ag, 6700 Ludwigshafen | METHOD FOR PRODUCING 4,4-DIMETHYL-TETRAHYDROFURAN-2,3-DION |
-
1963
- 1963-04-11 GB GB1466863A patent/GB1044338A/en not_active Expired
- 1963-04-13 CH CH469763A patent/CH427770A/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5508302A (en) * | 1994-09-28 | 1996-04-16 | American Home Products Corporation | Phospholipase A2 inhibitors |
Also Published As
Publication number | Publication date |
---|---|
CH427770A (en) | 1967-01-15 |
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