GB1080128A - Method of producing new nicotinic acid esters - Google Patents
Method of producing new nicotinic acid estersInfo
- Publication number
- GB1080128A GB1080128A GB27265/66A GB2726566A GB1080128A GB 1080128 A GB1080128 A GB 1080128A GB 27265/66 A GB27265/66 A GB 27265/66A GB 2726566 A GB2726566 A GB 2726566A GB 1080128 A GB1080128 A GB 1080128A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nicotinic acid
- acid esters
- producing new
- formula
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical class OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 229960003512 nicotinic acid Drugs 0.000 abstract 1
- 235000001968 nicotinic acid Nutrition 0.000 abstract 1
- 239000011664 nicotinic acid Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Processing Of Meat And Fish (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel compounds of the formula <FORM:1080128/C2/1> wherein R1 and R2 together represent an oxygen atom, or R1 represents a methyl or ethyl group and R2 represents the group of the formula <FORM:1080128/C2/2> are prepared by reacting nicotinic acid, or a derivative thereof, with a polyhydric alcohol of the formula <FORM:1080128/C2/3> or a derivative thereof, wherein R3 and R4 together represent an oxygen atom or R3 represents a methyl or ethyl group and R4 represents a hydroxymethyl group. Pharmaceutical compositions comprise a compound of the invention together with a pharmaceutically acceptable carrier.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8215/65*A SE323679B (en) | 1965-04-22 | 1965-04-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1080128A true GB1080128A (en) | 1967-08-23 |
Family
ID=20273451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB27265/66A Expired GB1080128A (en) | 1965-04-22 | 1966-06-17 | Method of producing new nicotinic acid esters |
Country Status (13)
| Country | Link |
|---|---|
| AT (1) | AT263010B (en) |
| BE (1) | BE682920A (en) |
| BR (1) | BR6680462D0 (en) |
| CH (1) | CH468383A (en) |
| DE (1) | DE1645915A1 (en) |
| DK (1) | DK112237B (en) |
| ES (1) | ES328732A1 (en) |
| FI (1) | FI47187C (en) |
| FR (1) | FR5624M (en) |
| GB (1) | GB1080128A (en) |
| IL (1) | IL25939A (en) |
| NO (1) | NO121496B (en) |
| SE (1) | SE323679B (en) |
-
1965
- 1965-04-22 SE SE8215/65*A patent/SE323679B/xx unknown
-
1966
- 1966-06-09 IL IL6625939A patent/IL25939A/en unknown
- 1966-06-15 DE DE19661645915 patent/DE1645915A1/en active Pending
- 1966-06-16 AT AT574266A patent/AT263010B/en active
- 1966-06-16 BR BR180462/66A patent/BR6680462D0/en unknown
- 1966-06-16 FI FI661592A patent/FI47187C/en active
- 1966-06-17 GB GB27265/66A patent/GB1080128A/en not_active Expired
- 1966-06-20 CH CH891266A patent/CH468383A/en unknown
- 1966-06-21 ES ES0328732A patent/ES328732A1/en not_active Expired
- 1966-06-21 NO NO66163571A patent/NO121496B/no unknown
- 1966-06-21 FR FR66315A patent/FR5624M/fr not_active Expired
- 1966-06-22 BE BE682920D patent/BE682920A/xx unknown
- 1966-06-22 DK DK322766AA patent/DK112237B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR6680462D0 (en) | 1973-06-28 |
| AT263010B (en) | 1968-07-10 |
| NO121496B (en) | 1971-03-08 |
| DK112237B (en) | 1968-11-25 |
| SE323679B (en) | 1970-05-11 |
| IL25939A (en) | 1970-06-17 |
| FI47187C (en) | 1973-10-10 |
| FR5624M (en) | 1967-12-18 |
| ES328732A1 (en) | 1967-04-01 |
| BE682920A (en) | 1966-12-01 |
| FI47187B (en) | 1973-07-02 |
| CH468383A (en) | 1969-02-15 |
| DE1645915A1 (en) | 1970-09-24 |
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