GB1040551A - 2-substituted 5-nitro furans - Google Patents

2-substituted 5-nitro furans

Info

Publication number
GB1040551A
GB1040551A GB810664A GB810664A GB1040551A GB 1040551 A GB1040551 A GB 1040551A GB 810664 A GB810664 A GB 810664A GB 810664 A GB810664 A GB 810664A GB 1040551 A GB1040551 A GB 1040551A
Authority
GB
United Kingdom
Prior art keywords
formulae
compound
substituted
compounds
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB810664A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE184564A external-priority patent/SE314381B/xx
Application filed by Pharmacia AB filed Critical Pharmacia AB
Publication of GB1040551A publication Critical patent/GB1040551A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

The invention comprises compounds of the formulae <FORM:1040551/C2/1> <FORM:1040551/C2/2> <FORM:1040551/C2/3> wherein R1, R2, R3 and R4\t each represents a hydrogen atom, one or two of the R1-, R2-, R3- and R4-hydrogen atoms being each possibly replaced by a C1- 5 alkyl group and one of the R2- and R3-hydrogen atoms being possibly replaced by the group -COR5, wherein R5 is a hydrogen atom or a possibly halogen-substituted C1- 3 alkyl group, and therapeutically useful salts thereof. The compounds are prepared by nitrating compounds of the formulae <FORM:1040551/C2/4> <FORM:1040551/C2/5> <FORM:1040551/C2/6> and, if desired, reacting the compound thus formed with a base or, if it does not contain an acyl group, with an acid, to produce the corresponding salt. When a compound of the Formulae I, II or III contains an acyl group, this may be split off by hydrolysis. Pharmaceutical compositions, having anti-bacterial activity, comprise a compound of the invention together with a pharmaceutical carrier. The compositions may be in the form of tablets, suspensions and capsules.
GB810664A 1963-02-28 1964-02-27 2-substituted 5-nitro furans Expired GB1040551A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE219363 1963-02-28
SE184564A SE314381B (en) 1964-02-15 1964-02-15

Publications (1)

Publication Number Publication Date
GB1040551A true GB1040551A (en) 1966-09-01

Family

ID=26654296

Family Applications (1)

Application Number Title Priority Date Filing Date
GB810664A Expired GB1040551A (en) 1963-02-28 1964-02-27 2-substituted 5-nitro furans

Country Status (6)

Country Link
CH (1) CH424795A (en)
DE (1) DE1445438B2 (en)
DK (1) DK107619C (en)
GB (1) GB1040551A (en)
NL (1) NL6401901A (en)
NO (1) NO115874B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3522251A (en) * 1968-04-03 1970-07-28 R & L Molecular Research Ltd Basic esters of 5-amino-3-(5'-nitrofur-2'-yl)isoxazole-4-carboxylic acid
US3522252A (en) * 1968-04-03 1970-07-28 R & L Molecular Research Ltd Basic esters of 5-alkanoylamino-3-(5'-nitrofur - 2' - yl)isoxazole - 4 - carboxylic acid

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3522251A (en) * 1968-04-03 1970-07-28 R & L Molecular Research Ltd Basic esters of 5-amino-3-(5'-nitrofur-2'-yl)isoxazole-4-carboxylic acid
US3522252A (en) * 1968-04-03 1970-07-28 R & L Molecular Research Ltd Basic esters of 5-alkanoylamino-3-(5'-nitrofur - 2' - yl)isoxazole - 4 - carboxylic acid

Also Published As

Publication number Publication date
DE1445438B2 (en) 1973-01-25
DK107619C (en) 1967-06-19
NL6401901A (en) 1964-08-31
CH424795A (en) 1966-11-30
NO115874B (en) 1968-12-23
DE1445438A1 (en) 1969-04-10

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