GB1028233A - 5-aminodibenzocycloheptene derivatives - Google Patents
5-aminodibenzocycloheptene derivativesInfo
- Publication number
- GB1028233A GB1028233A GB53464A GB53464A GB1028233A GB 1028233 A GB1028233 A GB 1028233A GB 53464 A GB53464 A GB 53464A GB 53464 A GB53464 A GB 53464A GB 1028233 A GB1028233 A GB 1028233A
- Authority
- GB
- United Kingdom
- Prior art keywords
- stands
- radical
- formula
- compound
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G9/00—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor
- A23G9/04—Production of frozen sweets, e.g. ice-cream
- A23G9/20—Production of frozen sweets, e.g. ice-cream the products being mixed with gas, e.g. soft-ice
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/33—Polycyclic acids
- C07C63/331—Polycyclic acids with all carboxyl groups bound to non-condensed rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Novel compounds of the formula <FORM:1028233/C2/1> wherein X stands for the radical -CH2.CHR- or -CH=CH-, wherein R stands for hydrogen or for an alkyl radical, wherein R1 stands for hydrogen or for an alkyl radical and wherein R2 stands for an alkyl or alkenyl radical, optionally substituted by a hydroxy radical, or wherein R1 and R2 are joined to form, together with the adjacent nitrogen atom, a heterocyclic ring, and wherein ring A may optionally be further substituted by a halogen atom or an alkyl radical, and the pharmaceutically-acceptable acid-addition salts thereof, are prepared by either, (a) reacting a compound of formula <FORM:1028233/C2/2> wherein X has the above meaning, Y stands for a halogen atom and ring A may be substituted as above, and an amine of the formula HNR1R2 wherein R1 and R2 have the meanings stated above; or (b) in the case of compounds of the first general formula above, where R1 stands for hydrogen and wherein R2 stands for the radical -CH.R3R4 and wherein R3 stands for hydrogen or an alkyl radical and R4 stands for an alkyl radical, optionally substituted by a hydroxy radical by interacting an amino derivative of the formula <FORM:1028233/C2/3> wherein X has the meaning stated in Claim 1 and wherein ring A may optionally be further substituted as above, and a carbonyl compound of the formula R3.CO.R4, wherein R3 and R4 have the meanings stated above, under reducing conditions. Compounds of the second general formula above are prepared by reacting the corresponding 5-hydroxy compound with a thionyl halide. Compounds of the second general formula above wherein Y is hydroxy are prepared by reduction of the corresponding keto compound. 2 - (1 - Methyl - 2 - phenyl ethyl) benzoic acid is prepared by reduction of the corresponding vinyl compound.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB53464A GB1028233A (en) | 1964-01-06 | 1964-01-06 | 5-aminodibenzocycloheptene derivatives |
| BE657924A BE657924A (en) | 1964-01-06 | 1965-01-05 | |
| NL6500085A NL6500085A (en) | 1964-01-06 | 1965-01-06 | |
| DK3565A DK109085C (en) | 1964-01-06 | 1965-01-06 | Process for the preparation of 5H-dibenzo [a, d] cycloheptenes or 5,11-dihydro-5H-dibenzo [a, d] cycloheptenes or acid addition salts thereof, which are basic substituted in the 5-position. |
| CH9065A CH456621A (en) | 1964-01-06 | 1965-01-06 | Process for the preparation of amine derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB53464A GB1028233A (en) | 1964-01-06 | 1964-01-06 | 5-aminodibenzocycloheptene derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1028233A true GB1028233A (en) | 1966-05-04 |
Family
ID=9706031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB53464A Expired GB1028233A (en) | 1964-01-06 | 1964-01-06 | 5-aminodibenzocycloheptene derivatives |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE657924A (en) |
| CH (1) | CH456621A (en) |
| DK (1) | DK109085C (en) |
| GB (1) | GB1028233A (en) |
| NL (1) | NL6500085A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ310008B6 (en) * | 2023-05-06 | 2024-05-01 | Fakultní nemocnice Hradec Králové | The N-methyl-D-aspartate receptor antagonists and their use |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1543035A1 (en) * | 1965-01-06 | 1969-09-25 | Hoffmann La Roche | Process for the preparation of dibenzocycloheptene compounds |
-
1964
- 1964-01-06 GB GB53464A patent/GB1028233A/en not_active Expired
-
1965
- 1965-01-05 BE BE657924A patent/BE657924A/xx unknown
- 1965-01-06 NL NL6500085A patent/NL6500085A/xx unknown
- 1965-01-06 CH CH9065A patent/CH456621A/en unknown
- 1965-01-06 DK DK3565A patent/DK109085C/en active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ310008B6 (en) * | 2023-05-06 | 2024-05-01 | Fakultní nemocnice Hradec Králové | The N-methyl-D-aspartate receptor antagonists and their use |
Also Published As
| Publication number | Publication date |
|---|---|
| DK109085C (en) | 1968-03-18 |
| BE657924A (en) | 1965-07-05 |
| CH456621A (en) | 1968-07-31 |
| NL6500085A (en) | 1965-07-07 |
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