GB1025245A - Aerosol device - Google Patents

Aerosol device

Info

Publication number
GB1025245A
GB1025245A GB32756/63A GB3275663A GB1025245A GB 1025245 A GB1025245 A GB 1025245A GB 32756/63 A GB32756/63 A GB 32756/63A GB 3275663 A GB3275663 A GB 3275663A GB 1025245 A GB1025245 A GB 1025245A
Authority
GB
United Kingdom
Prior art keywords
plunger
measuring chamber
container
sleeve
allow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB32756/63A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1025245A publication Critical patent/GB1025245A/en
Expired legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/44Valves specially adapted therefor; Regulating devices
    • B65D83/52Valves specially adapted therefor; Regulating devices for metering
    • B65D83/54Metering valves ; Metering valve assemblies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Nozzles (AREA)

Abstract

1,025,245. Delivering measured quantities of liquid. MERCK & CO. Aug. 19, 1963 [Aug. 31, 1962], No. 32756/63. Heading B8N. [Also in Divisions F1 and A5] An aerosol device for dispensing measured amounts of a substance comprises a manuallyactuated plunger 51, with a measuring chamber 77 therein, which is moved into the aerosol container 15 to allow the measuring chamber to fill through orifice 79 and is held in this position, Fig. 8, when the operating means 13 is released, by detent means 45, means being provided to release the detent means when dispensing of the measured amount is desired. The device is shown as an inhaling device for dispensing medicament into a mouth or nostril. The actuating means 13 is attached to a plunger 67, sealed by a diaphragm 73, which moves initially to drive any air out of the measuring chamber 77 before the plunger 51 is lifted into the container for filling of the measuring chamber. At the end of the upward movement of the member 13, a sleeve 87 is lifted to lock the detent balls 45 in position beneath inclined surfaces 59 on the plunger 51. When the means 13 is released the plunger 67 returns to its normal position to allow the measuring chamber 77 to fill and the surfaces 59 force the balls 45 outwardly to grip the lower end 95 of the sleeve 87 whereby the latter and the plunger 51 remain cocked with the chamber 77 retracted into the container 15. When suction is applied to the mouthpiece 17 sleeve 87 is forced down to release the balls 45 and allow plunger 51 to be moved down by the fluid pressure and by spring 81, whereby orifice 79 moves out of the container 15 past sealing diaphragm 31 and the contents of the measuring chamber 77 are discharged through passage 47 and spraying nozzle 109, Fig. 10 (not shown). As plunger 51 begins to move down, aperture 103 in sleeve 13 is opened to allow air to be inhaled with the medicament. In Fig. 11 (not shown), the detent balls are replaced by spring fingers 131 which are controlled by the suction actuated release sleeve 137. The container 15 is also adapted to receive a replaceable aerosol container 155 screwed therein and is provided with puncturing means 149. In Fig. 13, the plunger 251 is held cocked by a spring-loaded lever 284 which is released manually by button 296.
GB32756/63A 1962-08-31 1963-08-19 Aerosol device Expired GB1025245A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US220599A US3157179A (en) 1962-08-31 1962-08-31 Aerosol device

Publications (1)

Publication Number Publication Date
GB1025245A true GB1025245A (en) 1966-04-06

Family

ID=22824167

Family Applications (1)

Application Number Title Priority Date Filing Date
GB32756/63A Expired GB1025245A (en) 1962-08-31 1963-08-19 Aerosol device

Country Status (5)

Country Link
US (1) US3157179A (en)
DE (1) DE1287260B (en)
GB (1) GB1025245A (en)
NL (1) NL297349A (en)
SE (1) SE317467B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2139503A (en) * 1983-05-14 1984-11-14 Matsushita Electric Works Ltd Inhalator
WO2004093952A1 (en) * 2003-04-22 2004-11-04 Bespak Plc Dispensing apparatus

Families Citing this family (69)

* Cited by examiner, † Cited by third party
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US3361306A (en) * 1966-03-31 1968-01-02 Merck & Co Inc Aerosol unit dispensing uniform amounts of a medically active ingredient
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
BE758834A (en) * 1969-11-13 1971-05-12 Riker Laboratoires Inc AEROSOL DISPENSER ACTIVATED BY INHALATION
US3721240A (en) * 1970-11-10 1973-03-20 M Tamburri Mechanical smoking device
US3838686A (en) * 1971-10-14 1974-10-01 G Szekely Aerosol apparatus for inhalation therapy
IT1066105B (en) * 1976-08-13 1985-03-04 Sigma Tau Ind Farmaceuti INHALER FOR SUBSTANCES IN SPRAY PACKAGE
DE2835122C3 (en) * 1978-08-10 1982-02-18 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Inhalation device
DE2835135C3 (en) * 1978-08-10 1982-03-04 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Active substance storage for an inhalation device
US4576157A (en) * 1983-10-24 1986-03-18 Raghuprasad Puthalath K Oral inhalation apparatus
US4803978A (en) * 1985-08-09 1989-02-14 Johnson Iv John J Apparatus for actuating an inhaler
US5119806A (en) * 1987-05-12 1992-06-09 Glaxo Inc. Inhalation device
US5031610A (en) * 1987-05-12 1991-07-16 Glaxo Inc. Inhalation device
US5297542A (en) * 1989-06-22 1994-03-29 Raymond J. Bacon Aerosol dispensing device
FR2658081B1 (en) * 1990-02-09 1995-06-30 Pesenti Yvan AUTOMATION AND SYNCHRONIZATION DEVICE FOR AEROSOL APPARATUS WITH DOSING PUMP.
GB9020555D0 (en) * 1990-09-20 1990-10-31 Bespak Plc Dispensing apparatus
WO1994016757A2 (en) * 1991-03-05 1994-08-04 Miris Medical Corporation Apparatus for providing a timed release of an amount of aerosol medication
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
US5394866A (en) * 1991-03-05 1995-03-07 Aradigm Corporation Automatic aerosol medication delivery system and methods
US5450336A (en) * 1991-03-05 1995-09-12 Aradigm Corporation Method for correcting the drift offset of a transducer
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US6029661A (en) * 1991-08-26 2000-02-29 3M Innovative Properties Company Powder dispenser
US5522385A (en) * 1994-09-27 1996-06-04 Aradigm Corporation Dynamic particle size control for aerosolized drug delivery
US5822980A (en) * 1997-07-01 1998-10-20 Chen; Jack Device for reducing molecular pollutants in the gases from a combustion engine
GB2329450A (en) 1997-09-22 1999-03-24 Bespak Plc Improvements in or related to pressurised dispensing apparatus
FR2775668B1 (en) * 1998-03-04 2000-05-19 Tebro DEVICE FOR DISPENSING FLUID PRODUCT TRIGGERED BY INHALATION
US6234167B1 (en) 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
WO2001064182A2 (en) 2000-02-28 2001-09-07 Vectura Limited Improvements in or relating to the delivery of oral drugs
MY136453A (en) 2000-04-27 2008-10-31 Philip Morris Usa Inc "improved method and apparatus for generating an aerosol"
US6883516B2 (en) 2000-04-27 2005-04-26 Chrysalis Technologies Incorporated Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution
US6799572B2 (en) 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US6701921B2 (en) 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US7077130B2 (en) 2000-12-22 2006-07-18 Chrysalis Technologies Incorporated Disposable inhaler system
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US6779520B2 (en) * 2001-10-30 2004-08-24 Iep Pharmaceutical Devices Inc. Breath actuated dry powder inhaler
US6804458B2 (en) * 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
ES2633913T3 (en) 2002-03-22 2017-09-26 Clinical Designs Limited Cartridge fixing
US7497214B2 (en) * 2002-09-16 2009-03-03 3M Innovative Properties Company Aerosol dispensers and adaptors therefor
US7296567B2 (en) 2002-09-25 2007-11-20 3M Innovative Properties Company Breath actuated aerosol dispensers
US7367334B2 (en) 2003-08-27 2008-05-06 Philip Morris Usa Inc. Fluid vaporizing device having controlled temperature profile heater/capillary tube
GB0420529D0 (en) * 2004-09-16 2004-10-20 3M Innovative Properties Co Valve stems for metered dose dispensing valves
FR2888822B1 (en) * 2005-07-21 2010-04-02 Valois Sas FLUID PRODUCT DELIVERY VALVE
DE102006022002A1 (en) * 2006-05-10 2007-11-15 Boehringer Ingelheim International Gmbh Atomizers and methods for atomizing fluid
DE102007056263A1 (en) * 2007-11-22 2009-05-28 Siegfried Generics International Ag Dosing device for inhaling a powdery substance
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
CN102176939B (en) * 2008-10-08 2015-03-04 阿斯利康(瑞典)有限公司 Inhaler with audible indicator means
EP2414560B1 (en) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Method for coating a surface of a component
JP5763053B2 (en) 2009-05-18 2015-08-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Adapter, inhaler and atomizer
US8495998B2 (en) * 2009-06-17 2013-07-30 British American Tobacco (Investments) Limited Inhaler
AP3141A (en) 2009-11-25 2015-02-28 Boehringer Ingelheim Int Nebulizer
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011160932A1 (en) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nebulizer
WO2012130757A1 (en) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medical device comprising a container
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (en) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Atomiser with coding means
US9744313B2 (en) 2013-08-09 2017-08-29 Boehringer Ingelheim International Gmbh Nebulizer
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
MX2016014402A (en) 2014-05-07 2017-01-20 Boehringer Ingelheim Int Nebulizer and container.
WO2015169430A1 (en) 2014-05-07 2015-11-12 Boehringer Ingelheim International Gmbh Nebulizer
CN106255554B (en) 2014-05-07 2021-05-04 勃林格殷格翰国际有限公司 Container, sprayer and use
FR3028765B1 (en) 2014-11-21 2016-12-23 Aptar France Sas DEVICE FOR DISPENSING FLUID PRODUCT TRIGGERED BY INHALATION.
WO2017044897A1 (en) * 2015-09-10 2017-03-16 Impel Neuropharma Inc. In-line nasal delivery device
KR20200118032A (en) 2018-01-05 2020-10-14 임펠 뉴로파마 인코포레이티드 Intranasal delivery of dihydroergotamine by precise olfactory organ device

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US2535844A (en) * 1946-08-01 1950-12-26 John H Emerson Aspirator for administering medicine
US2932432A (en) * 1955-12-30 1960-04-12 Risdon Mfg Co Metering type aerosol spray dispenser
US3001524A (en) * 1956-03-21 1961-09-26 Riker Laboratories Inc Aerosol dispensing apparatus
US2872923A (en) * 1957-03-20 1959-02-10 Birch And Gattone Inc Means for administering pressurized medicaments, gases, combinations thereof and liquids into body cavities
GB878409A (en) * 1957-03-26 1961-09-27 United Drug And Chemical Compa Improvements in or relating to dispensing devices
US2892576A (en) * 1957-11-14 1959-06-30 Lawrence T Ward Metering button valve assembly
US2992645A (en) * 1958-05-06 1961-07-18 Benger Lab Ltd Disperser for powders
GB864392A (en) * 1958-11-10 1961-04-06 Rexall Drug Company Ltd Improvements in or relating to dispensing devices for aerosols

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2139503A (en) * 1983-05-14 1984-11-14 Matsushita Electric Works Ltd Inhalator
WO2004093952A1 (en) * 2003-04-22 2004-11-04 Bespak Plc Dispensing apparatus

Also Published As

Publication number Publication date
DE1287260B (en) 1969-01-16
NL297349A (en)
SE317467B (en) 1969-11-17
US3157179A (en) 1964-11-17

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