GB1016730A - Novel enamine steroids and processes for their preparation - Google Patents
Novel enamine steroids and processes for their preparationInfo
- Publication number
- GB1016730A GB1016730A GB42126/64A GB4212664A GB1016730A GB 1016730 A GB1016730 A GB 1016730A GB 42126/64 A GB42126/64 A GB 42126/64A GB 4212664 A GB4212664 A GB 4212664A GB 1016730 A GB1016730 A GB 1016730A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroid
- processes
- preparation
- diene
- steroids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- -1 enamine steroids Chemical class 0.000 title 1
- 150000001412 amines Chemical class 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- LUJVUUWNAPIQQI-UHFFFAOYSA-N (+)-androsta-1,4-diene-3,17-dione Natural products O=C1C=CC2(C)C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 LUJVUUWNAPIQQI-UHFFFAOYSA-N 0.000 abstract 1
- OKJCFMUGMSVJBG-ABEVXSGRSA-N Delta(1)-dihydrotestosterone Chemical compound C1C(=O)C=C[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CC[C@H]21 OKJCFMUGMSVJBG-ABEVXSGRSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- LUJVUUWNAPIQQI-QAGGRKNESA-N androsta-1,4-diene-3,17-dione Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 LUJVUUWNAPIQQI-QAGGRKNESA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000197 pyrolysis Methods 0.000 abstract 1
- 125000000467 secondary amino group Chemical class [H]N([*:1])[*:2] 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR951070A FR1381417A (fr) | 1963-10-18 | 1963-10-18 | Amines stéroïdes et procédé de préparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1016730A true GB1016730A (en) | 1966-01-12 |
Family
ID=8814690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB42126/64A Expired GB1016730A (en) | 1963-10-18 | 1964-10-15 | Novel enamine steroids and processes for their preparation |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3274176A (enExample) |
| CH (1) | CH437271A (enExample) |
| DE (2) | DE1618813A1 (enExample) |
| FR (1) | FR1381417A (enExample) |
| GB (1) | GB1016730A (enExample) |
| NL (2) | NL6411832A (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE548375T1 (de) * | 2004-01-16 | 2012-03-15 | Cedarburg Pharmaceuticals Inc | Exemestan und zwischenprodukte davon und verfahren zu dessen herstellung |
| US8168621B2 (en) | 2005-09-30 | 2012-05-01 | Endece, Llc | 6-substituted estradiol derivatives and methods of use |
| US20080119447A1 (en) * | 2005-09-30 | 2008-05-22 | James Yarger | 6-alkoxyalkyl estradiol derivatives and methods of use |
| US10174070B2 (en) * | 2005-09-30 | 2019-01-08 | Endece Llc | 6-substituted estradiol derivatives and methods of use |
| US20080275259A1 (en) * | 2007-05-04 | 2008-11-06 | Scinopharm Taiwan, Ltd | Process for preparing aromatase inhibitors |
| MX343059B (es) | 2010-09-14 | 2016-10-24 | Endece Llc | Derivados de desmetil-estradiol sustituido en 6 como agonistas de er-beta selectivos. |
-
0
- NL NL122154D patent/NL122154C/xx active
-
1963
- 1963-10-18 FR FR951070A patent/FR1381417A/fr not_active Expired
-
1964
- 1964-10-07 DE DE19641618813 patent/DE1618813A1/de active Pending
- 1964-10-07 DE DE19641468886 patent/DE1468886B1/de not_active Withdrawn
- 1964-10-09 CH CH1312464A patent/CH437271A/fr unknown
- 1964-10-12 NL NL6411832A patent/NL6411832A/xx unknown
- 1964-10-14 US US403936A patent/US3274176A/en not_active Expired - Lifetime
- 1964-10-15 GB GB42126/64A patent/GB1016730A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1468886B1 (de) | 1970-04-30 |
| FR1381417A (fr) | 1964-12-14 |
| DE1618813A1 (de) | 1971-02-25 |
| NL122154C (enExample) | |
| US3274176A (en) | 1966-09-20 |
| CH437271A (fr) | 1967-06-15 |
| NL6411832A (enExample) | 1965-04-20 |
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