GB1010751A - Pharmaceutically active carbonates and amides - Google Patents
Pharmaceutically active carbonates and amidesInfo
- Publication number
- GB1010751A GB1010751A GB31199/63A GB3119963A GB1010751A GB 1010751 A GB1010751 A GB 1010751A GB 31199/63 A GB31199/63 A GB 31199/63A GB 3119963 A GB3119963 A GB 3119963A GB 1010751 A GB1010751 A GB 1010751A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- benzodioxane
- group
- reacting
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001408 amides Chemical class 0.000 title 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 title 1
- 125000005877 1,4-benzodioxanyl group Chemical group 0.000 abstract 2
- MJCYUVOCINOVJH-UHFFFAOYSA-N 3-methyl-2,3-dihydro-1,4-benzodioxine Chemical compound C1=CC=C2OC(C)COC2=C1 MJCYUVOCINOVJH-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004185 ester group Chemical group 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- ICECVFQATRXXDW-UHFFFAOYSA-N 2-[2-hydroxyethyl-(3-methyl-2H-1,4-benzodioxin-3-yl)amino]ethanol Chemical compound OCCN(C1(COC2=C(O1)C=CC=C2)C)CCO ICECVFQATRXXDW-UHFFFAOYSA-N 0.000 abstract 1
- -1 4,4-disubstituted piperidine Chemical class 0.000 abstract 1
- DMCVVFIWYIKAEJ-UHFFFAOYSA-N 4-phenylpiperidine-4-carbonitrile Chemical compound C=1C=CC=CC=1C1(C#N)CCNCC1 DMCVVFIWYIKAEJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 abstract 1
- 229910052731 fluorine Chemical group 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000004679 hydroxides Chemical class 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- SUSQOBVLVYHIEX-UHFFFAOYSA-N phenylacetonitrile Chemical compound N#CCC1=CC=CC=C1 SUSQOBVLVYHIEX-UHFFFAOYSA-N 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US218119A US3166561A (en) | 1962-08-20 | 1962-08-20 | 1-[2-(1, 4-benzodioxanyl)-methyl]-4-phenyl-4-carbonylamino or 4-carbalkoxy amino piperidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1010751A true GB1010751A (en) | 1965-11-24 |
Family
ID=22813820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB31199/63A Expired GB1010751A (en) | 1962-08-20 | 1963-08-07 | Pharmaceutically active carbonates and amides |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3166561A (enExample) |
| BE (1) | BE636238A (enExample) |
| FR (1) | FR2984M (enExample) |
| GB (1) | GB1010751A (enExample) |
| NL (1) | NL296841A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002088132A1 (en) * | 2001-04-26 | 2002-11-07 | Wyeth | Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-ht1aantagonists |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4039676A (en) * | 1975-06-23 | 1977-08-02 | Ciba-Geigy Corporation | 2-piperidinoalkyl-1,4-benzodioxans |
| US4129655A (en) * | 1976-04-26 | 1978-12-12 | Ciba-Geigy Corporation | Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans |
| US4957928A (en) * | 1986-06-26 | 1990-09-18 | Ciba-Geigy Corporation | Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds |
| US5221745A (en) * | 1991-06-21 | 1993-06-22 | American Home Products Corp. | Psychotropic piperidinylmethyl benzodioxans |
| US5182292A (en) * | 1991-06-21 | 1993-01-26 | American Home Products Corporation | Psychotropic piperidinylmethyl benzodioxans |
| US5212170A (en) * | 1991-06-21 | 1993-05-18 | American Home Products Corporation | Psychotropic piperidinylmethyl benzodioxans |
| SI9300097B (en) * | 1992-02-27 | 2001-12-31 | Janssen Pharmaceutica Nv | (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines |
| US5703115A (en) * | 1993-02-19 | 1997-12-30 | Janssen Pharmaceutica, N.V. | (benzodioxan, benzofuran or benzopyran) alkylamino! alkyl substituted guanidines |
| US6303637B1 (en) * | 1998-10-30 | 2001-10-16 | Merck & Co., Inc. | Heterocyclic potassium channel inhibitors |
| EP3233077A4 (en) | 2014-12-19 | 2018-08-08 | The Broad Institute Inc. | Dopamine d2 receptor ligands |
-
0
- BE BE636238D patent/BE636238A/xx unknown
- NL NL296841D patent/NL296841A/xx unknown
-
1962
- 1962-08-20 US US218119A patent/US3166561A/en not_active Expired - Lifetime
-
1963
- 1963-08-07 GB GB31199/63A patent/GB1010751A/en not_active Expired
- 1963-08-19 FR FR945027A patent/FR2984M/fr active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002088132A1 (en) * | 2001-04-26 | 2002-11-07 | Wyeth | Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-ht1aantagonists |
| US6821981B2 (en) | 2001-04-26 | 2004-11-23 | Wyeth | Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]-quinoline as 5-HT1A antagonists |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2984M (fr) | 1964-12-07 |
| NL296841A (enExample) | |
| BE636238A (enExample) | |
| US3166561A (en) | 1965-01-19 |
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