GB1006385A - Isopropanols and the manufacture thereof - Google Patents
Isopropanols and the manufacture thereofInfo
- Publication number
- GB1006385A GB1006385A GB11160/64A GB1116064A GB1006385A GB 1006385 A GB1006385 A GB 1006385A GB 11160/64 A GB11160/64 A GB 11160/64A GB 1116064 A GB1116064 A GB 1116064A GB 1006385 A GB1006385 A GB 1006385A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyridyl
- methyl
- alkoxy
- methane
- halogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises compounds of the general formula <FORM:1006385/C2/1> wherein the symbol S represents substitution comprising a halogen atom or an alkyl, alkoxy or alkyl mercapto group or three alkoxy groups and the broken line denotes that such substitution is optional, and acid addition salts thereof; and the preparation thereof by reacting a (pyridyl-(4)-methyl)-alkali metal or -magnesium halide derivative with a compound of the formula <FORM:1006385/C2/2> wherein R represents a halogen atom or an alkoxy, benzyloxy or phenoxy group and S and the broken line have the significance given above and, if desired, converting the reaction product into an acid addition salt. [Pyridyl - (4) - methyl] - lithium is prepared by the interaction of pyridyl-(4)-methane and phenyl lithium in an ether benzene solution under an atmosphere of dry nitrogen. [Pyridyl - (4) - methyl] - magnesium bromide is prepared by the reaction of pyridyl-(4)-methane and ethyl magnesium bromide in tetrahydro-furan solution under reflux conditions. Pharmaceutical compositions for use as anti-parkinson agents when administered enterally or parenterally comprising the compound of the first general formula above and an inert diluent or exipient. The composition may be in the form of tablets, dragees, suppositories, capsules, solutions, emulsions or suspensions.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26602963A | 1963-03-18 | 1963-03-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1006385A true GB1006385A (en) | 1965-09-29 |
Family
ID=23012875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB11160/64A Expired GB1006385A (en) | 1963-03-18 | 1964-03-17 | Isopropanols and the manufacture thereof |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE645241A (en) |
| BR (1) | BR6457623D0 (en) |
| CH (1) | CH453357A (en) |
| DE (1) | DE1445891A1 (en) |
| DK (1) | DK112656B (en) |
| ES (1) | ES297720A1 (en) |
| FR (2) | FR3260M (en) |
| GB (1) | GB1006385A (en) |
| NL (1) | NL6402889A (en) |
-
1964
- 1964-03-06 CH CH291564A patent/CH453357A/en unknown
- 1964-03-10 DE DE19641445891 patent/DE1445891A1/en active Pending
- 1964-03-13 FR FR967225A patent/FR3260M/en active Active
- 1964-03-16 BE BE645241D patent/BE645241A/xx unknown
- 1964-03-16 FR FR967485A patent/FR1397328A/en not_active Expired
- 1964-03-17 GB GB11160/64A patent/GB1006385A/en not_active Expired
- 1964-03-17 ES ES297720A patent/ES297720A1/en not_active Expired
- 1964-03-17 BR BR157623/64A patent/BR6457623D0/en unknown
- 1964-03-18 NL NL6402889A patent/NL6402889A/xx unknown
- 1964-03-18 DK DK140064AA patent/DK112656B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR6457623D0 (en) | 1973-07-17 |
| DK112656B (en) | 1969-01-06 |
| CH453357A (en) | 1968-06-14 |
| DE1445891A1 (en) | 1968-11-28 |
| BE645241A (en) | 1964-09-16 |
| NL6402889A (en) | 1964-09-21 |
| ES297720A1 (en) | 1964-09-01 |
| FR1397328A (en) | 1965-04-30 |
| FR3260M (en) | 1965-04-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1464224A (en) | Triazolyl-alkanones and triazolylalkanols processes for their preparation and their use as fungicides | |
| GB1489394A (en) | Halogen-containing metal phthalocyanines and a process for their manufacture | |
| GB1421689A (en) | Imidazolyl-o,n-acetals and their salts processes for their preparation and their use as fungicides | |
| GB1013907A (en) | Alkene derivatives | |
| GB1069797A (en) | ª-aminoketone derivatives | |
| GB1006385A (en) | Isopropanols and the manufacture thereof | |
| ES392480A1 (en) | 1-(dimesitylmethyl)imidazole | |
| GB1124539A (en) | New substituted-hydrazino benzisothiazoles and process for preparing same | |
| ES313081A1 (en) | Phenyl-alpha-piperazino-alkanoates | |
| GB1378446A (en) | Process for the manufacture of dicyanovinyl compounds | |
| GB1502232A (en) | Substituted 2-phenylimino-1,3-dithiolanes process for their preparation and their use as ectoparasiticidal agents | |
| GB1070139A (en) | Novel imidazothiazole derivatives and a process for preparation thereof | |
| GB1052346A (en) | ||
| GB1058521A (en) | New amino azacycloheptanones and process for their production | |
| GB1390588A (en) | 1-alkyl-sulphonyl-2-trifluoromethylbenzimidazoles process for their production and their use as agents against ectoparasites | |
| GB1359644A (en) | 1,2-diphenyl-ethane derivatives | |
| ES354905A1 (en) | 4-aryl-4-aminoalkoxy-piperidines | |
| ES432366A1 (en) | Copper base metalorganic compounds and process for the preparation thereof | |
| GB959993A (en) | Camphor derivatives | |
| GB955353A (en) | Improvements in or relating to novel pyridine derivatives | |
| ES371448A1 (en) | Derivatives of acetic acid | |
| GB1475114A (en) | 4-amino-3-hydrazino-1,2,4-triazole derivatives methods for their preparation and compositions containing them | |
| GB669179A (en) | Organo silicon compounds | |
| GB1109310A (en) | Heterocyclic ethanols | |
| GB1352089A (en) | Bis-styryltriazoles their use for the optical brightening of organic materials and processes for their manufacture |