GB1005024A - Manufacture of naphthalene derivatives - Google Patents

Manufacture of naphthalene derivatives

Info

Publication number
GB1005024A
GB1005024A GB4002961A GB4002961A GB1005024A GB 1005024 A GB1005024 A GB 1005024A GB 4002961 A GB4002961 A GB 4002961A GB 4002961 A GB4002961 A GB 4002961A GB 1005024 A GB1005024 A GB 1005024A
Authority
GB
United Kingdom
Prior art keywords
methoxy
stands
formula
naphthyl
ethanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4002961A
Inventor
Ralph Howe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to NL285180D priority Critical patent/NL285180A/xx
Priority to BE624532D priority patent/BE624532A/xx
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Priority to GB4002961A priority patent/GB1005024A/en
Priority to CH1301062A priority patent/CH433207A/en
Priority to DK482462A priority patent/DK108425C/en
Publication of GB1005024A publication Critical patent/GB1005024A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention comprises (a) 2-isopropyl-amino - 1 - (1 - methoxy - 2 - naphthyl) - ethanol and pharmaceutical preparations containing it, and (b) the preparation of compounds of the general formula <FORM:1005024/C2/1> (wherein R1 stands for a hydrogen atom or a methyl group, R2 stands for an alkyl group containing not more than four carbon atoms, and the naphthalene nucleus may optionally bear an alkoxy substituent) and acid addition salts thereof by reducing a compound of the formula <FORM:1005024/C2/2> (wherein the naphthalene nucleus may optionally bear an alkoxy substituent) in the presence of an amine or hydroxylamine of the formula R3NR1R2 (wherein R3 stands for a hydrogen atom or a hydroxyl group), optionally followed by acid addition salt formation. 1 - Methoxy - 2 - naphthylglyoxal hydrate is prepared bc heating 2 - acetyl - 1 - methoxy-naphthalene with selenium dioxide, dioxan and water. 2 - Isopropylamino - 1 - (1 - methoxy - 2 - naphthyl) ethanol is of value in the treatment or propylaxis of coronary artery disease, and may be administered orally or parenterally in the form of pharmaceutical preparations (e.g. tablets, pills, capsules, aqueous or oily solutions or suspensions, emulsions or dispersible powders) containing it together with a diluent or carrier. The Provisional Specification defines the invention in wider terms. Specifications 909,357 and 1,005,025 are referred to.
GB4002961A 1961-11-08 1961-11-08 Manufacture of naphthalene derivatives Expired GB1005024A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
NL285180D NL285180A (en) 1961-11-08
BE624532D BE624532A (en) 1961-11-08
GB4002961A GB1005024A (en) 1961-11-08 1961-11-08 Manufacture of naphthalene derivatives
CH1301062A CH433207A (en) 1961-11-08 1962-11-07 Process for the production of naphthalene derivatives
DK482462A DK108425C (en) 1961-11-08 1962-11-08 Process for the preparation of naphthalene derivatives or their salts.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4002961A GB1005024A (en) 1961-11-08 1961-11-08 Manufacture of naphthalene derivatives

Publications (1)

Publication Number Publication Date
GB1005024A true GB1005024A (en) 1965-09-22

Family

ID=10412812

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4002961A Expired GB1005024A (en) 1961-11-08 1961-11-08 Manufacture of naphthalene derivatives

Country Status (5)

Country Link
BE (1) BE624532A (en)
CH (1) CH433207A (en)
DK (1) DK108425C (en)
GB (1) GB1005024A (en)
NL (1) NL285180A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI523607B (en) * 2010-04-15 2016-03-01 陶氏農業科學公司 Agricultural fumigation using a multilayer film including a pvdc vapor barrier

Also Published As

Publication number Publication date
NL285180A (en)
CH433207A (en) 1967-04-15
BE624532A (en)
DK108425C (en) 1967-12-11

Similar Documents

Publication Publication Date Title
GB1058822A (en) 3-amino-2-hydroxypropoxy heterocyclic derivatives
GB1171509A (en) Pyridine Derivatives
GB852795A (en) Substituted furyl-thiadiazoles and a process for their production
GB1005024A (en) Manufacture of naphthalene derivatives
GB1199065A (en) Theophylline and Theobromine Compounds and processes for their production
GB939901A (en) Improvements in or relating to amino pyrazoles
GB1016071A (en) New guanidine derivatives and process for preparing the same
US3287468A (en) 2-nitroimidazoles and process
GB1059968A (en) Naphthalene derivatives
GB945909A (en) Morphinone and codeinone derivatives
GB935525A (en) Anthranilic acids and method for producing the same
GB1033920A (en) Novel derivatives of triphenylethanols
GB1014881A (en) 1,3-diazaphenothiazines and method
GB1019225A (en) Aminoethanol derivatives
GB984291A (en) Aminoethanol derivatives
GB1077811A (en) Tetrahydro-1,3,5-thiadiazine-2-thiones and process for their manufacture
GB1005026A (en) Naphthalene and indane derivatives
GB1091109A (en) New derivative of phenylbutazone and its preparation
GB852727A (en) Analgesic compounds
GB1005021A (en) Naphthalene derivatives
GB1046001A (en) Propanolamine derivatives
GB994889A (en) Piperazine derivatives
GB1025908A (en) New amino-steroid compounds and processes for their preparation
GB1055741A (en) Pharmaceutical compositions comprising substituted urea derivatives
GB1082943A (en) Derivatives of 7-aminocephalosporanic acid