GB1003950A - Process for the production of basic dibenzo-oxepin and dibenzo-thiepin derivatives - Google Patents

Process for the production of basic dibenzo-oxepin and dibenzo-thiepin derivatives

Info

Publication number
GB1003950A
GB1003950A GB28137/64A GB2813764A GB1003950A GB 1003950 A GB1003950 A GB 1003950A GB 28137/64 A GB28137/64 A GB 28137/64A GB 2813764 A GB2813764 A GB 2813764A GB 1003950 A GB1003950 A GB 1003950A
Authority
GB
United Kingdom
Prior art keywords
compounds
formula
general formula
compound
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28137/64A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1003950A publication Critical patent/GB1003950A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/12—[b,e]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB28137/64A 1963-07-09 1964-07-08 Process for the production of basic dibenzo-oxepin and dibenzo-thiepin derivatives Expired GB1003950A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB0072596 1963-07-09

Publications (1)

Publication Number Publication Date
GB1003950A true GB1003950A (en) 1965-09-08

Family

ID=6977520

Family Applications (1)

Application Number Title Priority Date Filing Date
GB28137/64A Expired GB1003950A (en) 1963-07-09 1964-07-08 Process for the production of basic dibenzo-oxepin and dibenzo-thiepin derivatives

Country Status (9)

Country Link
US (1) US3438981A (US07732459-20100608-C00017.png)
AT (1) AT249071B (US07732459-20100608-C00017.png)
BE (1) BE650278A (US07732459-20100608-C00017.png)
CH (1) CH436339A (US07732459-20100608-C00017.png)
DK (1) DK116447B (US07732459-20100608-C00017.png)
FR (1) FR88751E (US07732459-20100608-C00017.png)
GB (1) GB1003950A (US07732459-20100608-C00017.png)
LU (1) LU46467A1 (US07732459-20100608-C00017.png)
NL (1) NL6407758A (US07732459-20100608-C00017.png)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235796A2 (en) * 1986-03-03 1987-09-09 Kyowa Hakko Kogyo Co., Ltd. Dibenz [b,e] oxepin derivative and antiallergic and antiinflammatory agent
EP1154135A2 (en) * 2000-05-11 2001-11-14 General Electric Company Methods and apparatus for supplying cooling air to turbine engines
US7271176B2 (en) 1998-09-04 2007-09-18 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use thereof
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7732459B2 (en) 2002-11-13 2010-06-08 Millennium Pharmaceuticals, Inc. CCR1 antagonists and methods of use therefor
CN104975951A (zh) * 2014-04-08 2015-10-14 通用电气公司 用于利用燃料加热的间隙控制的方法和设备

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3872102A (en) * 1971-11-04 1975-03-18 En Nom Collectif Science Union Tricyclic compounds of aliphatic w-amino alcohols
IL94768A (en) * 1989-06-19 1995-08-31 Wellcome Found Use of Reliable History Transformed by Aril for the Preparation of Pharmaceuticals
WO1993000811A1 (en) * 1991-07-01 1993-01-21 The General Hospital Corporation Invertebrate phenylethanolamine transporter and the use thereof
US5574173A (en) * 1993-12-06 1996-11-12 Schering Corporation Tricyclic derivatives, compositions and methods of use
CN1088459C (zh) * 1996-10-04 2002-07-31 诺沃挪第克公司 1,4－二取代的哌嗪
EP2218442A1 (en) 2005-11-09 2010-08-18 CombinatoRx, Inc. Methods, compositions, and kits for the treatment of ophthalmic disorders
US8513299B2 (en) 2006-05-19 2013-08-20 Pernix Sleep, Inc. Methods of using low-dose doxepin for the improvement of sleep
US20100179215A1 (en) 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin isomers and isomeric mixtures and methods of using the same to treat sleep disorders
US20100179214A1 (en) 2006-05-19 2010-07-15 Somaxon Pharmaceuticals, Inc. Doxepin trans isomers and isomeric mixtures and methods of using the same to treat sleep disorders
US20090042972A1 (en) * 2006-05-19 2009-02-12 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
US20090042971A1 (en) * 2006-05-19 2009-02-12 Somaxon Pharmaceuticals, Inc. Method of using low-dose doxepin for the improvement of sleep
WO2007136845A2 (en) * 2006-05-19 2007-11-29 Somaxon Pharmaceuticals, Inc. Low-dose doxepin for treatment of sleep disorders in elderly patients
CA2693992C (en) * 2006-07-20 2017-01-31 Somaxon Pharmaceuticals, Inc. Methods of improving the pharmacokinetics of doxepin
WO2008085567A1 (en) * 2006-10-04 2008-07-17 Somaxon Pharmaceuticals, Inc. Methods of using low-dose doxepin for the improvement of sleep
US20100105614A1 (en) 2006-10-25 2010-04-29 Somaxon Pharmaceuticals, Inc. Ultra low dose doxepin and methods of using the same to treat sleep disorders
US20110077200A1 (en) 2006-12-06 2011-03-31 Somaxon Pharmaceuticals, Inc. Combination therapy using low-dose doxepin for the improvement of sleep
US20090074862A1 (en) 2007-04-13 2009-03-19 Luigi Schioppi Low-dose doxepin formulations and methods of making and using the same
EP2222342B1 (en) * 2007-11-28 2014-03-26 Nektar Therapeutics Oligomer-tricyclic conjugates
WO2010013240A1 (en) 2008-07-31 2010-02-04 Dekel Pharmaceuticals Ltd. Compositions and methods for treating inflammatory disorders
WO2011091050A1 (en) 2010-01-19 2011-07-28 Nektar Therapeutics Oligomer-tricyclic conjugates
US9090535B2 (en) 2010-12-10 2015-07-28 Nektar Therapeutics Hydroxylated tricyclic compounds
CN115124500B (zh) * 2022-08-08 2024-01-30 苏州弘森药业股份有限公司 一种精制多塞平的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE623259A (US07732459-20100608-C00017.png) *
US3193549A (en) * 1958-07-07 1965-07-06 Sterling Drug Inc 10-[(1-piperidyl)lower-alkyl]-trifluoromethylphenothiazines

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235796A3 (en) * 1986-03-03 1988-09-21 Kyowa Hakko Kogyo Co., Ltd. Dibenz ûb,e¨ oxepin derivative and antiallergic and antiinflammatory agent
US5116863A (en) * 1986-03-03 1992-05-26 Kyowa Hakko Kogyo Co., Ltd. Dibenz[b,e]oxepin derivative and pharmaceutical compositions thereof
EP0235796A2 (en) * 1986-03-03 1987-09-09 Kyowa Hakko Kogyo Co., Ltd. Dibenz [b,e] oxepin derivative and antiallergic and antiinflammatory agent
US7271176B2 (en) 1998-09-04 2007-09-18 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use thereof
EP1154135A2 (en) * 2000-05-11 2001-11-14 General Electric Company Methods and apparatus for supplying cooling air to turbine engines
EP1154135A3 (en) * 2000-05-11 2003-06-04 General Electric Company Methods and apparatus for supplying cooling air to turbine engines
US8653096B2 (en) 2001-11-21 2014-02-18 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use thereof
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US9663537B2 (en) 2001-11-21 2017-05-30 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use
US8058287B2 (en) 2001-11-21 2011-11-15 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7977350B2 (en) 2002-11-13 2011-07-12 Millennium Pharmaceuticals, Inc. CCR1 antagonists and methods of use therefor
US8394817B2 (en) 2002-11-13 2013-03-12 Millennium Pharmaceuticals, Inc. CCR1 antagonists and methods of use therefor
US9334283B2 (en) 2002-11-13 2016-05-10 Millennium Pharmaceuticals, Inc. CCR1 antagonists and methods of use thereof
US7732459B2 (en) 2002-11-13 2010-06-08 Millennium Pharmaceuticals, Inc. CCR1 antagonists and methods of use therefor
CN104975951A (zh) * 2014-04-08 2015-10-14 通用电气公司 用于利用燃料加热的间隙控制的方法和设备
US9963994B2 (en) 2014-04-08 2018-05-08 General Electric Company Method and apparatus for clearance control utilizing fuel heating

Also Published As

Publication number Publication date
US3438981A (en) 1969-04-15
LU46467A1 (US07732459-20100608-C00017.png) 1972-01-01
BE650278A (US07732459-20100608-C00017.png) 1965-01-08
CH436339A (de) 1967-05-31
FR88751E (US07732459-20100608-C00017.png) 1967-06-07
AT249071B (de) 1966-09-26
DK116447B (da) 1970-01-12
NL6407758A (US07732459-20100608-C00017.png) 1965-01-11

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