GB1000782A - Pharmaceutical compositions containing alkyl derivatives of phlorophenone - Google Patents
Pharmaceutical compositions containing alkyl derivatives of phlorophenoneInfo
- Publication number
- GB1000782A GB1000782A GB13346/61A GB1334661A GB1000782A GB 1000782 A GB1000782 A GB 1000782A GB 13346/61 A GB13346/61 A GB 13346/61A GB 1334661 A GB1334661 A GB 1334661A GB 1000782 A GB1000782 A GB 1000782A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pharmaceutical compositions
- phlorophenone
- compositions containing
- containing alkyl
- alkyl derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 title 1
- CRUILBNAQILVHZ-UHFFFAOYSA-N 1,2,3-trimethoxybenzene Chemical compound COC1=CC=CC(OC)=C1OC CRUILBNAQILVHZ-UHFFFAOYSA-N 0.000 abstract 2
- JUVKXUAMWAIQQK-UHFFFAOYSA-N 2,3,3-trimethoxy-2-methyl-1-phenylpropan-1-one Chemical compound COC(C(C(=O)C1=CC=CC=C1)(C)OC)OC JUVKXUAMWAIQQK-UHFFFAOYSA-N 0.000 abstract 1
- LOUMGDLTGMVMTK-UHFFFAOYSA-N O(C)C(CC(=O)C1=CC=CC=C1)(OC)OC Chemical compound O(C)C(CC(=O)C1=CC=CC=C1)(OC)OC LOUMGDLTGMVMTK-UHFFFAOYSA-N 0.000 abstract 1
- 230000002921 anti-spasmodic effect Effects 0.000 abstract 1
- 239000003420 antiserotonin agent Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- UYXAWHWODHRRMR-UHFFFAOYSA-N hexobarbital Chemical compound O=C1N(C)C(=O)NC(=O)C1(C)C1=CCCCC1 UYXAWHWODHRRMR-UHFFFAOYSA-N 0.000 abstract 1
- 229960002456 hexobarbital Drugs 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 230000000147 hypnotic effect Effects 0.000 abstract 1
- 150000002466 imines Chemical class 0.000 abstract 1
- LRDFRRGEGBBSRN-UHFFFAOYSA-N isobutyronitrile Chemical compound CC(C)C#N LRDFRRGEGBBSRN-UHFFFAOYSA-N 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- KRIOVPPHQSLHCZ-UHFFFAOYSA-N propiophenone Chemical class CCC(=O)C1=CC=CC=C1 KRIOVPPHQSLHCZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 229940030010 trimethoxybenzene Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
- C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Trimethoxyisobutyrophenone is prepared by reacting trimethoxybenzene and isobutyronitrile and hydrolysing the imine. Similarly are prepared trimethoxy-aceto- and propiophenones.ALSO:Pharmaceutical compositions comprise compounds of the formula <FORM:1000782/A5-A6/1> (where R and R1 represent the same or different alkyl radicals) and a solid pharmaceutical carrier. Examples are given of tablets, capsules, pills and suppositories containing trimethoxy-aceto-propio-and -isobutyro-phenones, which have antispasmodic activity. Trimethoxypropiophenone also shows some antiserotonin action and potentiates the hypnotic effect of hexobarbital.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB13346/61A GB1000782A (en) | 1961-04-13 | 1961-04-13 | Pharmaceutical compositions containing alkyl derivatives of phlorophenone |
FR893542A FR2129M (en) | 1961-04-13 | 1962-04-06 | Composition containing alkylated derivatives of phlorophenone. |
BE616322A BE616322A (en) | 1961-04-13 | 1962-04-12 | Compositions containing alkylated derivatives of phlorophenone |
OA50762A OA00656A (en) | 1961-04-13 | 1964-12-05 | Compositions containing alkylated derivatives of phlorophenone. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB13346/61A GB1000782A (en) | 1961-04-13 | 1961-04-13 | Pharmaceutical compositions containing alkyl derivatives of phlorophenone |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1000782A true GB1000782A (en) | 1965-08-11 |
Family
ID=10021287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB13346/61A Expired GB1000782A (en) | 1961-04-13 | 1961-04-13 | Pharmaceutical compositions containing alkyl derivatives of phlorophenone |
Country Status (4)
Country | Link |
---|---|
BE (1) | BE616322A (en) |
FR (1) | FR2129M (en) |
GB (1) | GB1000782A (en) |
OA (1) | OA00656A (en) |
-
1961
- 1961-04-13 GB GB13346/61A patent/GB1000782A/en not_active Expired
-
1962
- 1962-04-06 FR FR893542A patent/FR2129M/en not_active Expired
- 1962-04-12 BE BE616322A patent/BE616322A/en unknown
-
1964
- 1964-12-05 OA OA50762A patent/OA00656A/en unknown
Also Published As
Publication number | Publication date |
---|---|
OA00656A (en) | 1966-07-15 |
FR2129M (en) | 1963-11-12 |
BE616322A (en) | 1962-07-31 |
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