GB0823309D0 - Functionalising reagents and their uses - Google Patents

Functionalising reagents and their uses

Info

Publication number
GB0823309D0
GB0823309D0 GBGB0823309.0A GB0823309A GB0823309D0 GB 0823309 D0 GB0823309 D0 GB 0823309D0 GB 0823309 A GB0823309 A GB 0823309A GB 0823309 D0 GB0823309 D0 GB 0823309D0
Authority
GB
United Kingdom
Prior art keywords
functionalising
reagents
functionalising reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0823309.0A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Bath
Original Assignee
University of Bath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Bath filed Critical University of Bath
Priority to GBGB0823309.0A priority Critical patent/GB0823309D0/en
Publication of GB0823309D0 publication Critical patent/GB0823309D0/en
Priority to PCT/GB2009/002924 priority patent/WO2010070300A2/en
Priority to PL15151649T priority patent/PL2886132T3/pl
Priority to ES09795797.1T priority patent/ES2556328T3/es
Priority to ES15151649.9T priority patent/ES2674099T3/es
Priority to US13/140,690 priority patent/US8785595B2/en
Priority to HK12105931.7A priority patent/HK1165435B/xx
Priority to JP2011541582A priority patent/JP5877712B2/ja
Priority to CN201410643896.5A priority patent/CN104558098B/zh
Priority to PL09795797T priority patent/PL2373675T3/pl
Priority to EP15151649.9A priority patent/EP2886132B1/en
Priority to EP09795797.1A priority patent/EP2373675B1/en
Priority to CN200980154905.1A priority patent/CN102317305B/zh
Priority to US14/315,784 priority patent/US9212148B2/en
Priority to JP2015137984A priority patent/JP6240122B2/ja
Priority to HK15110783.3A priority patent/HK1210026B/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
GBGB0823309.0A 2008-12-19 2008-12-19 Functionalising reagents and their uses Ceased GB0823309D0 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
GBGB0823309.0A GB0823309D0 (en) 2008-12-19 2008-12-19 Functionalising reagents and their uses
CN200980154905.1A CN102317305B (zh) 2008-12-19 2009-12-21 硫醇基官能化试剂及其用途
HK12105931.7A HK1165435B (en) 2008-12-19 2009-12-21 Thiol-functionalising reagents and their uses
CN201410643896.5A CN104558098B (zh) 2008-12-19 2009-12-21 硫醇基官能化试剂及其用途
ES09795797.1T ES2556328T3 (es) 2008-12-19 2009-12-21 Reactivos con funcionalidad tiol y sus usos
ES15151649.9T ES2674099T3 (es) 2008-12-19 2009-12-21 Reactivos con funcionalidad tiol y sus usos
US13/140,690 US8785595B2 (en) 2008-12-19 2009-12-21 Functionalising reagents and their uses
PCT/GB2009/002924 WO2010070300A2 (en) 2008-12-19 2009-12-21 Functionalising reagents and their uses
JP2011541582A JP5877712B2 (ja) 2008-12-19 2009-12-21 官能基化試薬およびその使用
PL15151649T PL2886132T3 (pl) 2008-12-19 2009-12-21 Reagenty funkcjonalizujące tiole oraz ich zastosowania
PL09795797T PL2373675T3 (pl) 2008-12-19 2009-12-21 Reagenty funkcjonalizujące tiole oraz ich zastosowania
EP15151649.9A EP2886132B1 (en) 2008-12-19 2009-12-21 Thiol-functionalising reagents and their uses
EP09795797.1A EP2373675B1 (en) 2008-12-19 2009-12-21 Thiol-functionalising reagents and their uses
US14/315,784 US9212148B2 (en) 2008-12-19 2014-06-26 Functionalizing reagents and their uses
JP2015137984A JP6240122B2 (ja) 2008-12-19 2015-07-09 官能基化試薬およびその使用
HK15110783.3A HK1210026B (en) 2008-12-19 2015-11-02 Thiol-functionalising reagents and their uses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0823309.0A GB0823309D0 (en) 2008-12-19 2008-12-19 Functionalising reagents and their uses

Publications (1)

Publication Number Publication Date
GB0823309D0 true GB0823309D0 (en) 2009-01-28

Family

ID=40343997

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0823309.0A Ceased GB0823309D0 (en) 2008-12-19 2008-12-19 Functionalising reagents and their uses

Country Status (8)

Country Link
US (2) US8785595B2 (enExample)
EP (2) EP2373675B1 (enExample)
JP (2) JP5877712B2 (enExample)
CN (2) CN104558098B (enExample)
ES (2) ES2556328T3 (enExample)
GB (1) GB0823309D0 (enExample)
PL (2) PL2373675T3 (enExample)
WO (1) WO2010070300A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0823309D0 (en) 2008-12-19 2009-01-28 Univ Bath Functionalising reagents and their uses
GB201007356D0 (en) 2010-04-30 2010-06-16 Leverton Licence Holdings Ltd Conjugated factor VIIa
AU2012294448A1 (en) 2011-08-08 2014-03-06 Boyce Thompson Institute For Plant Research Small molecule compounds for the control of nematodes
MX2014001503A (es) 2011-08-08 2015-01-14 California Inst Of Techn Compuestos de moleculas pequeñas que controlan los nematodos patogenos de plantas e insectos.
EP2907823A1 (en) * 2014-02-14 2015-08-19 Gene Signal International SA Polypeptide fragments of 168A-T2 and compositions comprising them for use in treating cancer
GB201419108D0 (en) * 2014-10-27 2014-12-10 Glythera Ltd Materials and methods relating to linkers for use in antibody drug conjugates
EP3503904A4 (en) 2016-08-25 2020-03-25 California Institute of Technology ASCAROSIDE TREATMENT OF EOSINOPHILIC OESOPHAGITIS
EP3829647A1 (en) 2018-07-31 2021-06-09 Astrazeneca AB Linkers and conjugates
US12473323B2 (en) 2019-05-17 2025-11-18 California Institute Of Technology Ascaroside derivatives and methods of use
CN115998707A (zh) * 2021-10-21 2023-04-25 福州大学 一种聚二硫多肽纳米粒及其制备方法和多肽药物口服制剂
CN115181091A (zh) * 2022-06-21 2022-10-14 江苏联环药业股份有限公司 一种贝他斯汀的制备方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
CA1236454A (en) * 1984-06-27 1988-05-10 John J. Tsai Monomeric cationic glycoside derivatives
US4719272A (en) * 1984-06-27 1988-01-12 National Starch And Chemical Corporation Monomeric cationic glycoside derivatives
JPS61134325A (ja) 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5079361A (en) * 1987-01-15 1992-01-07 Celltech Limited Thiol-reactive cross-linking reagents
DE3942355A1 (de) * 1989-12-21 1991-06-27 Boehringer Mannheim Gmbh N- und o-substituierte aminophenolderivate, zwischenprodukte zu deren herstellung, deren verwendung als hydrolasesubstrate, ein entsprechendes bestimmungsverfahren und hierfuer geeignetes diagnostisches mittel
EP0575545B1 (en) 1991-03-15 2003-05-21 Amgen Inc. Pegylation of polypeptides
DK0672142T3 (da) 1992-12-04 2001-06-18 Medical Res Council Multivalente og multispecifikke bindingsproteiner samt fremstilling og anvendelse af disse
US5446090A (en) * 1993-11-12 1995-08-29 Shearwater Polymers, Inc. Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
US6309646B1 (en) * 1996-05-09 2001-10-30 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Protein-polysaccharide conjugate vaccines and other immunological reagents prepared using homobifunctional and heterobifunctional vinylsulfones, and processes for preparing the conjugates
US6602498B2 (en) * 2000-02-22 2003-08-05 Shearwater Corporation N-maleimidyl polymer derivatives
WO2003025133A2 (en) 2001-09-14 2003-03-27 Mimeon, Inc. Methods of making glycolmolecules with enhanced activities and uses thereof
US20040214228A9 (en) 2001-09-14 2004-10-28 Ganesh Venkataraman Methods of evaluating glycomolecules for enhanced activities
CN1630530A (zh) 2002-01-18 2005-06-22 比奥根艾迪克Ma公司 聚亚烷基聚合物及其用途
NZ538624A (en) * 2002-09-09 2007-01-26 Nektar Therapeutics Al Corp Water-soluble polymer alkanals
JP2004262781A (ja) * 2003-02-28 2004-09-24 Noguchi Inst 蛍光糖鎖プローブ
US20050074895A1 (en) 2003-09-05 2005-04-07 Bio-Rad Laboratories, Inc. Alkyl-substituted vinyl pyridines for mass-coded tagging of proteins
CN101223137A (zh) * 2005-07-11 2008-07-16 默克公司 制备氢化异二氢吲哚速激肽受体拮抗剂的方法
GB0823309D0 (en) 2008-12-19 2009-01-28 Univ Bath Functionalising reagents and their uses
US9209965B2 (en) 2014-01-14 2015-12-08 Microsemi Semiconductor Ulc Network interface with clock recovery module on line card

Also Published As

Publication number Publication date
JP6240122B2 (ja) 2017-11-29
CN102317305A (zh) 2012-01-11
WO2010070300A2 (en) 2010-06-24
CN104558098B (zh) 2020-06-30
HK1165435A1 (zh) 2012-10-05
ES2674099T3 (es) 2018-06-27
EP2373675A2 (en) 2011-10-12
US20140364586A1 (en) 2014-12-11
US8785595B2 (en) 2014-07-22
JP5877712B2 (ja) 2016-03-08
US9212148B2 (en) 2015-12-15
EP2886132A1 (en) 2015-06-24
JP2015221812A (ja) 2015-12-10
PL2886132T3 (pl) 2018-09-28
CN102317305B (zh) 2016-03-23
EP2886132B1 (en) 2018-04-04
EP2373675B1 (en) 2015-10-21
CN104558098A (zh) 2015-04-29
HK1210026A1 (en) 2016-04-15
ES2556328T3 (es) 2016-01-15
PL2373675T3 (pl) 2016-03-31
JP2012512858A (ja) 2012-06-07
WO2010070300A3 (en) 2010-10-14
US20120101254A1 (en) 2012-04-26

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)