GB0011203D0 - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
GB0011203D0
GB0011203D0 GBGB0011203.7A GB0011203A GB0011203D0 GB 0011203 D0 GB0011203 D0 GB 0011203D0 GB 0011203 A GB0011203 A GB 0011203A GB 0011203 D0 GB0011203 D0 GB 0011203D0
Authority
GB
United Kingdom
Prior art keywords
chemical compounds
compounds
general formula
invention preferably
activity against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0011203.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rega Foundation
University College Cardiff Consultants Ltd
Cardiff University
Original Assignee
Rega Foundation
University College Cardiff Consultants Ltd
Cardiff University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rega Foundation, University College Cardiff Consultants Ltd, Cardiff University filed Critical Rega Foundation
Priority to GBGB0011203.7A priority Critical patent/GB0011203D0/en
Publication of GB0011203D0 publication Critical patent/GB0011203D0/en
Priority to JP2001582349A priority patent/JP2003532735A/ja
Priority to DE60101223T priority patent/DE60101223T2/de
Priority to PT01928079T priority patent/PT1280813E/pt
Priority to DK01928079T priority patent/DK1280813T3/da
Priority to AU54945/01A priority patent/AU780879B2/en
Priority to ES01928079T priority patent/ES2210153T3/es
Priority to US10/275,635 priority patent/US7019135B2/en
Priority to AT01928079T priority patent/ATE254132T1/de
Priority to CA002406633A priority patent/CA2406633A1/en
Priority to EP01928079A priority patent/EP1280813B1/en
Priority to NZ521877A priority patent/NZ521877A/en
Priority to TR2003/02313T priority patent/TR200302313T4/xx
Priority to PCT/GB2001/002004 priority patent/WO2001085749A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/14—Pyrrolo-pyrimidine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GBGB0011203.7A 2000-05-09 2000-05-09 Chemical compounds Ceased GB0011203D0 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
GBGB0011203.7A GB0011203D0 (en) 2000-05-09 2000-05-09 Chemical compounds
PCT/GB2001/002004 WO2001085749A1 (en) 2000-05-09 2001-05-08 Anti-viral pyrimidine nucleoside analogues
ES01928079T ES2210153T3 (es) 2000-05-09 2001-05-08 Analogos de nucleosidos de pirimidina de accion antiviral.
AT01928079T ATE254132T1 (de) 2000-05-09 2001-05-08 Antivirale pyrimidin nucleoside derivate
PT01928079T PT1280813E (pt) 2000-05-09 2001-05-08 Analogos de nucleosidos de pirimidina antivirais
DK01928079T DK1280813T3 (da) 2000-05-09 2001-05-08 Antivirale pyrimidin-nukleosidanaloger
AU54945/01A AU780879B2 (en) 2000-05-09 2001-05-08 Anti-viral pyrimidine nucleoside analogues
JP2001582349A JP2003532735A (ja) 2000-05-09 2001-05-08 抗ウイルスピリミジンヌクレオシド類
US10/275,635 US7019135B2 (en) 2000-05-09 2001-05-08 Anti-viral pyrimidine nucleoside analogues
DE60101223T DE60101223T2 (de) 2000-05-09 2001-05-08 Antivirale pyrimidin nucleoside derivate
CA002406633A CA2406633A1 (en) 2000-05-09 2001-05-08 Anti-viral pyrimidine nucleoside analogues
EP01928079A EP1280813B1 (en) 2000-05-09 2001-05-08 Anti-viral pyrimidine nucleoside analogues
NZ521877A NZ521877A (en) 2000-05-09 2001-05-08 Pyrimidine nucleoside analogues, their use in treating viral infection and preparation process thereof
TR2003/02313T TR200302313T4 (tr) 2000-05-09 2001-05-08 Antivirütik pirimidin nükleosid analogları

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0011203.7A GB0011203D0 (en) 2000-05-09 2000-05-09 Chemical compounds

Publications (1)

Publication Number Publication Date
GB0011203D0 true GB0011203D0 (en) 2000-06-28

Family

ID=9891276

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0011203.7A Ceased GB0011203D0 (en) 2000-05-09 2000-05-09 Chemical compounds

Country Status (14)

Country Link
US (1) US7019135B2 (https=)
EP (1) EP1280813B1 (https=)
JP (1) JP2003532735A (https=)
AT (1) ATE254132T1 (https=)
AU (1) AU780879B2 (https=)
CA (1) CA2406633A1 (https=)
DE (1) DE60101223T2 (https=)
DK (1) DK1280813T3 (https=)
ES (1) ES2210153T3 (https=)
GB (1) GB0011203D0 (https=)
NZ (1) NZ521877A (https=)
PT (1) PT1280813E (https=)
TR (1) TR200302313T4 (https=)
WO (1) WO2001085749A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7462605B2 (en) 1998-01-23 2008-12-09 Celmed Oncology (Usa), Inc. Phosphoramidate compounds and methods of use
CA2317505C (en) 1998-01-23 2011-01-04 Newbiotics, Inc. Enzyme catalyzed therapeutic agents
AU774492B2 (en) 1999-07-22 2004-07-01 Celmed Oncology (Usa) Inc. Methods for treating therapy-resistant tumors
US6683061B1 (en) 1999-07-22 2004-01-27 Newbiotics, Inc. Enzyme catalyzed therapeutic activation
GB0009486D0 (en) 2000-04-17 2000-06-07 Univ Cardiff Chemical compounds
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
HUE033832T2 (en) 2002-11-15 2018-01-29 Idenix Pharmaceuticals Llc 2'-methyl nucleosides in combination with interferon and Flaviviridae mutation
GB0609178D0 (en) * 2006-05-09 2006-06-21 Univ Cardiff Novel compounds
US20080261913A1 (en) 2006-12-28 2008-10-23 Idenix Pharmaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of liver disorders
EP2691409B1 (en) 2011-03-31 2018-02-21 Idenix Pharmaceuticals LLC. Compounds and pharmaceutical compositions for the treatment of viral infections
GB201111779D0 (en) * 2011-07-08 2011-08-24 Univ Cardiff Chemical compounds
TW201329096A (zh) 2011-09-12 2013-07-16 Idenix Pharmaceuticals Inc 經取代羰氧基甲基磷酸醯胺化合物及用於治療病毒感染之藥學組成物
US8507460B2 (en) 2011-10-14 2013-08-13 Idenix Pharmaceuticals, Inc. Substituted 3′,5′-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
US9296778B2 (en) 2012-05-22 2016-03-29 Idenix Pharmaceuticals, Inc. 3′,5′-cyclic phosphate prodrugs for HCV infection
WO2013177188A1 (en) 2012-05-22 2013-11-28 Idenix Pharmaceuticals, Inc. 3',5'-cyclic phosphoramidate prodrugs for hcv infection
CA2873315A1 (en) 2012-05-22 2013-11-28 Idenix Pharamaceuticals, Inc. D-amino acid compounds for liver disease
SG11201407336PA (en) 2012-05-25 2015-03-30 Janssen Sciences Ireland Uc Uracyl spirooxetane nucleosides
WO2014052638A1 (en) 2012-09-27 2014-04-03 Idenix Pharmaceuticals, Inc. Esters and malonates of sate prodrugs
KR102001280B1 (ko) 2012-10-08 2019-07-17 아이데닉스 파마슈티칼스 엘엘씨 Hcv 감염에 대한 2'-클로로 뉴클레오시드 유사체
WO2014066239A1 (en) 2012-10-22 2014-05-01 Idenix Pharmaceuticals, Inc. 2',4'-bridged nucleosides for hcv infection
EP2935304A1 (en) 2012-12-19 2015-10-28 IDENIX Pharmaceuticals, Inc. 4'-fluoro nucleosides for the treatment of hcv
US9309275B2 (en) 2013-03-04 2016-04-12 Idenix Pharmaceuticals Llc 3′-deoxy nucleosides for the treatment of HCV
US9339541B2 (en) 2013-03-04 2016-05-17 Merck Sharp & Dohme Corp. Thiophosphate nucleosides for the treatment of HCV
WO2014160484A1 (en) 2013-03-13 2014-10-02 Idenix Pharmaceuticals, Inc. Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
EP2981542B1 (en) 2013-04-01 2021-09-15 Idenix Pharmaceuticals LLC 2',4'-fluoro nucleosides for the treatment of hcv
US10005779B2 (en) 2013-06-05 2018-06-26 Idenix Pharmaceuticals Llc 1′,4′-thio nucleosides for the treatment of HCV
WO2015017713A1 (en) 2013-08-01 2015-02-05 Idenix Pharmaceuticals, Inc. D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
WO2015161137A1 (en) 2014-04-16 2015-10-22 Idenix Pharmaceuticals, Inc. 3'-substituted methyl or alkynyl nucleosides for the treatment of hcv

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62255499A (ja) * 1986-04-28 1987-11-07 Teijin Ltd 螢光性ヌクレオシド又はヌクレオチド
GB9708611D0 (en) * 1997-04-28 1997-06-18 Univ Cardiff Chemical compounds
GB9716231D0 (en) * 1997-07-31 1997-10-08 Amersham Int Ltd Base analogues

Also Published As

Publication number Publication date
DE60101223D1 (de) 2003-12-18
TR200302313T4 (tr) 2004-01-21
CA2406633A1 (en) 2001-11-15
ES2210153T3 (es) 2004-07-01
PT1280813E (pt) 2004-03-31
EP1280813A1 (en) 2003-02-05
NZ521877A (en) 2004-11-26
AU780879B2 (en) 2005-04-21
WO2001085749A1 (en) 2001-11-15
US7019135B2 (en) 2006-03-28
EP1280813B1 (en) 2003-11-12
JP2003532735A (ja) 2003-11-05
US20030176370A1 (en) 2003-09-18
AU5494501A (en) 2001-11-20
ATE254132T1 (de) 2003-11-15
DE60101223T2 (de) 2004-09-02
DK1280813T3 (da) 2004-03-22

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)